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From Diabetes Care to Diabetes Cure

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  • From Diabetes Care to Diabetes Cure

    Front. Endocrinol., 22 January 2018 | https://doi.org/10.3389/fendo.2017.00381

    From Diabetes Care to Diabetes Cure?The Integration of Systems Biology, eHealth, and Behavioral Change


    From a biological view, most of the processes involved in insulin resistance, which drives the pathobiology of type 2 diabetes, are reversible. This theoretically makes the disease reversible and curable by changing dietary habits and physical activity, particularly when adopted early in the disease process. Yet, this is not fully implemented and exploited in health care due to numerous obstacles.

    This article reviews the state of the art in all areas involved in a diabetes cure-focused therapy and discusses the scientific and technological advancements that need to be integrated into a systems approach sustainable lifestyle-based healthcare system and economy.

    The implementation of lifestyle as cure necessitates personalized and sustained lifestyle adaptations, which can only be established by a systems approach, including all relevant aspects (personalized diagnosis and diet, physical activity and stress management, self-empowerment, motivation, participation and health literacy, all facilitated by blended care and ehealth).

    Introduction of such a systems approach in type 2 diabetes therapy not only requires a concerted action of many stakeholders but also a change in healthcare economy, with new winners and losers. A ?call for action? is put forward to actually initiate this transition.

    The solution provided for type 2 diabetes is translatable to other lifestyle-related disorders.


    LINK TO FULL PAPER

    From a biological view, most of the processes involved in insulin resistance, which drives the pathobiology of type 2 diabetes, are reversible. This theoretically makes the disease reversible and curable by changing dietary habits and physical activity, particularly when adopted early in the disease process. Yet, this is not fully implemented and exploited in healthcare due to numerous obstacles. This paper reviews the state of the art in all areas involved in a diabetes cure-focused therapy and discusses the scientific and technological advancements that need to be integrated into a systems approach sustainable lifestyle-based healthcare system and economy. The implementation of lifestyle as cure necessitates personalized and sustained lifestyle adaptations, which can only be established by a systems approach, including all relevant aspects (personalized diagnosis and diet, physical activity and stress management, self-empowerment, motivation, participation and health literacy, all facilitated by blended care and e-health). Introduction of such a systems approach in type 2 diabetes therapy not only requires a concerted action of many stakeholders, but also a change in healthcare economy, with new winners and losers. A ?call for action? is put forward to actually initiate this transition. The solution provided for type 2 diabetes is translatable to other lifestyle related disorders.
    ?Addressing chronic disease is an issue of human rights ? that must be our call to arms"
    Richard Horton, Editor-in-Chief The Lancet

    ~~~~ Twitter:@GertvanderHoek ~~~ GertvanderHoek@gmail.com ~~~
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