Announcement

Collapse
No announcement yet.

Vitamin D and diabetes mellitus: Causal or casual association?

Collapse
X
  • Filter
  • Time
  • Show
Clear All
new posts

  • Vitamin D and diabetes mellitus: Causal or casual association?

    Rev Endocr Metab Disord. 2017 Jan 7. doi: 10.1007/s11154-016-9403-y. [Epub ahead of print]


    Grammatiki M1, Rapti E1, Karras S1, Ajjan RA2, Kotsa K3,4.

    Abstract

    The incidence of both type 2 and type 1 diabetes mellitus has been increasing worldwide. Vitamin D deficiency, or the awareness of its prevalence, has also been increasing.

    Vitamin D may have a role in the pathogenic mechanisms predisposing to type 2 diabetes by modulating insulin resistance and/or pancreatic β-cell function.

    Vitamin D status or elements involved in its activation or transport may also be involved in the development of type 1 diabetes mellitus through immunomodulatory role .

    Based on these observations a potential association between vitamin D and diabetes has been hypothesized. In this review we discuss up to date evidence linking vitamin D with the development of diabetes.

    Moreover, the role of vitamin D supplementation in the prevention of both types of diabetes is analysed together with its role in improving glycemic control in diabetic patients.

    ​We also address the potential role of vitamin D deficiency in the development of macro- and microvascular complications in diabetes.

    Finally, we provide recommendation for Vitamin D therapy in diabetes in view of current evidence and highlight areas for potential future research in this area.



    Rev Endocr Metab Disord. 2017 Jan 7. doi: 10.1007/s11154-016-9403-y. [Epub ahead of print] Review
    “Addressing chronic disease is an issue of human rights – that must be our call to arms"
    Richard Horton, Editor-in-Chief The Lancet

    ~~~~ Twitter:@GertvanderHoek ~~~ GertvanderHoek@gmail.com ~~~
Working...
X