Timor-Leste: 2022 Dengue

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Dengue outbreak in Timor-Leste with more cases and deaths than in 2021
The dengue outbreak that is affecting Timor-Leste has already caused practically as many deaths this month as in the whole of the last two years and with more cases than those recorded in the whole of 2021.
01/27/22 11:03 ‧ 28 mins ago by Lusa

Data from the Ministry of Health updated today indicate that since January 1 there have been 18 deaths due to dengue fever across the country, with a total of 1,035 cases, while last year there were 11 deaths and 901 cases.

In 2020, there were 1,451 cases with 10 deaths, and the mortality rate, which measures the percentage of deaths from disease cases, is 1.7, compared to 1.2 in 2021 and 0.7 in 2020.

The largest share of cases, almost 700, are registered in Dili with about half of these in the Dom Aleixo area.

The data show that children under 14 continue to be the most affected, with 316 cases among children aged 5 to 14, 284 among children aged 1 to 4 years and 50 among children under one year.

The outbreak, which authorities admit could continue for the next few months, is putting pressure on health resources, especially in Dili, with hundreds of patients in various locations, including spaces used in the past to respond to Covid-19.

Most cases in Dili (576) are dengue fever, with 58 cases of hemorrhagic fever and 64 of "dengue shock syndrome", these two being the most serious cases.

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Source: https://www.who.int/emergencies/dise...---timor-leste

Dengue - Timor-Leste
4 February 2022

Timor-Leste has reported a surge of dengue cases since late 2021, at unusually high levels compared to previous years. There were 1451 reported cases and 10 deaths (CFR 0.7%) in 2020 and 901 cases and 11 deaths (CFR 1.2%) in 2021. In January 2022 alone 1286 cases were reported, of which 790 (61.4%) were children under the age of 14 years, 142 were severe dengue cases and 20 fatalities were reported (case fatality ratio 1.6%). The majority of the cases who presented to the hospital were diagnosed based on the clinical signs and symptoms. Dili municipality, which includes the capital city of Timor-Leste, reported the highest number of cases (857 cases 66.6%), followed by Manatuto municipality (92, 7.2%).
Dengue is endemic in Timor-Leste year-round, with peak transmission reported from December to April during the hottest months of the year (Figure 1). The ongoing monsoon season may increase mosquito density and the likelihood of further transmission of dengue in the next few months. In previous outbreaks between 2005 and 2012, two co-circulating serotypes, dengue virus 1 (DENV-1) and dengue virus 3 (DENV-3), were reported. Information on circulating serotypes has not been available since 2012.
Figure 1. Dengue cases reported in Timor-Leste, 1 January 2016 - 31 January 2022
Source: WHO Country Office in Timor-Leste, WHO Regional Office for South-East Asia




Public health response

The Ministry of Health has undertaken several response activities including:

• Strengthening clinical management as the top priority. WHO supported the government to train health care workers in clinical management. A series of additional clinical management trainings will be conducted.
• Drafting the national dengue control guidelines with support from WHO, which includes the clinical management algorithm.
• Conducting a nationwide information, education and communication campaign to disseminate information about prevention and home care for dengue.
• WHO supported 60 public health inspectors to conduct vector control and source reduction activities in the community, including distributing larvicides, fumigating malathion (mosquito adulticide) in residential quarters and mobilizing communities and volunteers to clean up water containers and the environment.

WHO risk assessment

Dengue is a mosquito-borne viral infection that is caused by four DENV serotypes (DENV 1, DENV 2, DENV 3 and DENV 4). Aedes aegypti and Aedes albopictus are widely adapted vectors for urban and peri-urban environments. Infection with one serotype provides long-term immunity to the homologous serotype but not to the other serotypes. Sequential infections put people at greater risk for severe dengue.
Although dengue in Timor-Leste is not unexpected, the significant daily increase in the number of dengue cases and the rate of hospitalization in the current outbreak are unusual. The number of reported cases between 1 December 2021 to 31 January 2022 is substantially higher compared to the same periods in previous years since 2016. As dengue is endemic in Timor-Leste, the population may be at risk of secondary infection and possible serious complications if not treated promptly and adequately.
There is no specific treatment for dengue. Early recognition of dengue virus infection and appropriate clinical management can reduce the severity of disease and mortality among dengue cases. Given the limited health care capacity in-country, poor access to health care, and COVID-19 and other diseases pressuring health capacity, there is a high risk of serious health impacts and an increased number of severe and fatal dengue cases. Co-infections with SARS-CoV-2 and DENV can also be expected.
Due to strict international travel restrictions in response to COVID-19, cross-border movement of people is limited. However, international spread by vectors or asymptomatic travellers cannot be ruled out because Timor-Leste shares a land border with Indonesia where dengue is also endemic and the primary vectors are present.

WHO advice

This outbreak underscores the need for improved vector surveillance, enhanced laboratory capacity for better detection, increased bed capacity in hospitals, sensitized health care providers on case management and improved surveillance of acute febrile illness to better assess disease burden and seasonality patterns. Establishing sentinel sites for systematically testing and subtyping dengue virus will support the detection and response to dengue in affected areas.
The prevention and control of dengue depends on effective vector control. WHO promotes the strategic approach known as Integrated Vector Management (IVM) to control mosquito vectors, including Aedes subspecies, for larvae and adult mosquitoes. Enhanced IVM involves removing potential breeding sites, reducing vector populations, and minimizing individual exposure (i.e., environmental management and source reduction, and chemical control measures). Vector control activities should focus on all areas where there is human-vector contact such as residences, workplaces, schools and hospitals. Vector control activities can include covering, draining and cleaning household water storage containers on a weekly basis, as well as chlorination and application of suitable larvicides/insecticides for water storage. Community-led cleaning activities should be encouraged involving community groups, students, religious groups among others. Space spraying with insecticide can be deployed as an emergency measure.
Although dengue is not spread from person to person, mosquitoes can become infected after it bites someone with DENV. This cycle, therefore, makes the infected mosquito capable of spreading dengue within the household and the neighbourhood leading to clusters of cases. During outdoor activities, mosquito repellents may be applied to exposed skin or to clothing. While indoors, WHO recommends the use of mosquito repellents, household insecticide aerosol products or mosquito coils. Using window and door screens and air conditioning can also reduce bites.
WHO does not recommend that any general travel or trade restrictions be applied on Timor-Leste based on the information available for this event...