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France - Interview with Professor Didier Raoult - Marseille: Clostridium difficile has a strong pandemic potential

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  • France - Interview with Professor Didier Raoult - Marseille: Clostridium difficile has a strong pandemic potential

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    Interview with Professor Didier Raoult

    Marseille: Clostridium difficile has a strong potential pandemic

    Bruno Martrette | Published October 7, 2013

    The Clostridium difficile O27 spreads in Marseille causing severe diarrhea , or even death in the most sensitive. The bacteria concerned mainly because of its pandemic nature .

    A panic is sweeping the Marseille hospitals. Since March 2013, the O27 strain of Clostridium difficile , a bacterium that causes severe diarrhea , is indeed believed to be the cause of three deaths in the Bouches -du- Rhone, according to the Regional Health Agency of Provence Alpes - Cote d'Azur. In addition, 41 people have been infected with this bacterium. Given this situation , the first controversy over the numbers begin .

    According to Professor Didier Raoult , head of the Laboratory of Microbiology Hospital Marseille , " the number of deaths would be High . " Contacted by pourquoidocteur , this Marseille virologist says his concerns about the O27 toxin Clostridium difficile , which is" highly contagious "and has " a strong pandemic potential. "

    The resistance of the strain to antibiotics : a therapeutic problem
    Professor Didier Raoult : The Clostridium difficile O27 poses a problem for physicians because it is a multidrug-resistant bacteria. Faced with a case of infection, health professionals may have a therapeutic worries because often there is an effective antibiotic : colimycin . Unfortunately , it can also quickly become resistant to this antibiotic . There are several strains of this bacterium, which are of Israel , for example , which became fully resistant to all types of antibiotics . In this case , we are really in a therapeutic impasse.

    027 toxin is epidemic , see Pandemic
    Professor Didier Raoult : There is a clone, a mutant among all who have Clostridium difficile toxin , called " O27 ". It appeared there was a little more than ten years , and worries scientists because it is epidemic , or even pandemic . It is highly contagious and that is why it has reached the world. In addition, the O27 strain is often associated with high mortality . It was still a mortality rate of 30% with the first cases reported in France . It is an agent of epidemic and thus global pandemic. He had so far spared France , but one episode case in Lille in 2006, which still caused 23 deaths in the end. Since then he was gone, without that we can explain how or why too . And then he reappeared .

    The Regional Health Agency PACA behind in the number of suspicious deaths ?
    Professor Didier Raoult : We , according to our data , we know that there has already been six deaths in the University Hospital of Marseille , which could be related to Clostridium difficile O27 . And with my contacts in homes, we were informed by another two new deaths in some of these institutions in the PACA region. So , at a minimum , the results already achieved 8 deaths. But in a related death in bacteria , the problem is always the same, is that the imputablit? . Each time, Clostridium difficile is one of the cofactors of death associated with old age and various existing conditions.

    Why the PACA region is the only one affected ?
    Professor Didier Raoult : Regarding Clostridium difficile , it is only in Marseille to search for because we are far ahead technically . For now, the detection of the O27 strain is not refunded. PACA , we do it because it is the best center in the detection of epidemics in France . But these bacteria are probably in many other regions, but it is likely that nobody knows . Finally, Marseille is a crossroads of people who brews a lot of people . These flows of people obviously favor the spread of viruses .

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