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  • Chandipura virus

    Chandipura virus

    Chandipura virus

    Virus classification
    Group: Group V ((-)ssRNA)
    Order: Mononegavirales
    Family: Rhabdoviridae
    Genus: Vesiculovirus
    Species: Chandipura virus


    Chandipura virus is a member of the Rhabdoviridae family that is associated with an encephalitic illness in humans.

    It was first identified in 1965 after isolation from the blood of two patients from Chandipura village in Maharashtra state, India (Bhatt et al,1967) and has been associated with a number of otherwise unexplained outbreaks of encephalitic illness in central India.

    The most recent occurred in Andhra Pradesh and Maharashtra in June-August of 2003 with 329 children affected and 183 deaths. Further sporadic cases and deaths in children were observed in Gujarat state in 2004.

    Chandipura virus has been isolated from sandflies in India and West Africa (Fontenille et al, 1994) and is probably spread through its bite. The presence of the virus in Africa indicates a wide distribution although no human cases have been observed outside of India.

    The significance of Chandipura virus as a human pathogen is unresolved due to doubts over its role in the 2003 and 2004 outbreaks.





    Definition of Chandipura virus

    Chandipura virus: A virus that causes fever, symptoms similar to those of flu, and acute encephalitis (inflammation of the brain). Chandipura virus was first isolated in 1965 in a village in Maharashtra State, India. Since then, the virus has been reported in adjoining states in central India.

    The likely vector (carrier) of the virus is the female phlebotomine sandfly. The virus has been detected in sandflies in Senegal and Nigeria as well as in India. In 2003 Chandipura virus was responsible for an outbreak in southern India in which 329 children developed acute encephalitis and 183 died. The disease progressed rapidly from an influenza-like illness to coma and death.

    Chandipura virus is a member of the Vesiculovirus genus of the family Rhabdoviridae. This virus should be considered as an important emerging pathogen.





    Details on the outbreak in India in 2004 :




    Another illness associated with sandflies is Leishmaniasis , or Kala Azar, or Black Fever, see this thread:

    ?Addressing chronic disease is an issue of human rights ? that must be our call to arms"
    Richard Horton, Editor-in-Chief The Lancet

    ~~~~ Twitter:@GertvanderHoek ~~~ GertvanderHoek@gmail.com ~~~
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