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Identify new ways to combat Anthrax in the United States
Chicago. - The University of Michigan (UM) found a new way to block the ability of the bacterium Bacillus anthracis that causes anthrax, to capture iron, vital for their survival, and the characteristics that make it cause disease. Researchers Institute of Life Sciences at UM, said that this finding could be created antibiotics to prevent or treat in a more effective anthrax infections, known in Spanish as anthrax, a contagious disease, acute and severe. now has the opportunity to develop powerful anti-infective agents, the coordinator said the researchers, David Sherman, in an article published in the Journal of Biological Chemistr y. "The anthrax remains a security threat because there are inadequate responses to designed natural forms of the organism resistant to drugs, "said the expert. "The possibility of having a new target for drugs may lead to the development of broad spectrum antibiotics that are required before the growth of infectious agents resistant to current as is the case of anthrax, "he said. Although a treatment for anthrax is still far, the researchers used a high throughput screening at the Center for Chemical Genomics, Institute of Life Sciences at UM, to identify potential drugs more effective. "We are evaluating active extracts of a large library of natural products and hope to have new structures of molecules of antibiotics too soon," added Sherman. The study is funded by the Regional Center of the Great Lakes for Biodefense and Emerging Infectious Diseases , in order to identify new antibiotics and vaccines of small molecules against biological warfare agents and other high-risk infectious microbes. The results of this research led to establish a similar approach in the search for new antibiotics against Staphylococcus aureus , causing a multi-resistant infection. anthrax (anthrax in English) is a contagious disease, acute and severe, which can affect humans and is caused by Bacillus anthracis. The g ravedad of anthrax in humans varies according to the form the rate of infection and treatment. E l Cutaneous anthrax is the most common manifestation of the disease and has a low mortality, but inhalation anthrax is lethal in most cases. The e sporas the Bacillus anthracis s have been investigated as biological warfare agents and have been used in a terrorist attack.