Ebola Virus NP Real-Time RT-PCR Assay
Centers for Disease Control and Prevention
For Use Under an Emergency Use Authorization Only
Instructions for Use
(this a very technical guide to testing, but it includes guidance on interpreting results)
(further on page 16)
.
Centers for Disease Control and Prevention
For Use Under an Emergency Use Authorization Only
Instructions for Use
(this a very technical guide to testing, but it includes guidance on interpreting results)
(page 16)
Interpretation of rRT-PCR test results must account for the possibility of false-negative and false-positive results. False-negative results can arise from:?
poor sample collection or
?
degradation of the viral RNA during shipping or storage or
?
specimen collection conducted prior to symptom onset.
?
failure to follow the authorized assay procedures
?
failure to use authorized extraction kit and platform
Interpretation of rRT-PCR test results must account for the possibility of false-negative and false-positive results. False-negative results can arise from:?
poor sample collection or
?
degradation of the viral RNA during shipping or storage or
?
specimen collection conducted prior to symptom onset.
?
failure to follow the authorized assay procedures
?
failure to use authorized extraction kit and platform
Negative results do not preclude infection with Ebola virus and should not be used as the sole basis of a patient treatment/management decision. All results should be interpreted by a trained professional in conjunction with review of the patient?s history and clinical signs and symptoms.
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