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N Engl J Med. Ebola ? A Growing Threat?

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  • N Engl J Med. Ebola ? A Growing Threat?

    [Source: The New England Journal of Medicine, full page: (LINK). Extract.]


    Ebola ? A Growing Threat?

    Heinz Feldmann, M.D.

    May 7, 2014DOI: 10.1056/NEJMp1405314

    The recent emergence of Zaire ebolavirus in West Africa1 has come as a surprise in a region more commonly known for its endemic Lassa fever, another viral hemorrhagic fever caused by an Old World arenavirus. Yet the region has seen previous ebolavirus activity (see map Outbreaks or Episodes of Filovirus Infections.). In the mid-1990s, scientists discovered C?te d'Ivoire ebolavirus (now known as Ta? Forest ebolavirus) as a cause of a single reported nonfatal case in a researcher who performed a necropsy on an infected chimpanzee. The episode initiated a major research investigation in and around the Ta? Forest region ? an effort that failed to identify the reservoir of this new Ebola species. Since that incident, West African countries have not reported any evidence of the presence of ebolavirus.