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Zhong Nanshan: This winter flu into the end of the new tetravalent vaccine is an emergency research and development
2018-01-17 08:48 Source: South Network share it
Since late December last year, a flu has swept across the country. Influenced by the popularity of Type A Influenza in previous years, what is the fierce trend of Type B Influenza prevailing this year? What are the current epidemic characteristics of type B influenza? Flu vaccination there is no need for vaccination?
Zhong Nanshan, an academician of the Chinese Academy of Engineering, said in an interview with a reporter today that the current pandemic flu is of a type that has not yet been covered by the flu vaccine and that there is a slight change in the flu virus itself.
"The flu pandemic from the end of last year to early this year is now near the end of the period, and I believe it will be completed by the end of the month." The current vaccine research and development organization is urgently developing a new tetravalent vaccine that covers the epidemic type of influenza this winter, "said Dr. Zhong Nanshan.
Flu-like cases were more than double the same period last year
But far from the high prevalence of a stream in 2009
In this round of influenza epidemic, some media, especially since media coverage, compared this year's flu epidemic with the 2003 SARS and the 2009 influenza pandemic. According to the National Influenza sentinel hospital test results show that the current positive rate of influenza virus up to 40%, mainly B type. According to China CDC test data confirmed in recent weeks the national out-patient, emergency reported influenza virus than the same period the previous three years.
"So far, the number of influenza-like cases monitored by the hospital is more than double that of the same period of last year, and the predominant strain of pandemic is influenza type B. There are more patients infected, but very few cases of severe cases are caused," said Zhong Nanshan. It is less scientific to equate this winter's flu epidemic with SARS or the 2009 pandemic worldwide.
Zhong Nanshan: This winter flu into the end of the new tetravalent vaccine is an emergency research and development
In the 2009 influenza pandemic, the number of flu-like cases monitored by the hospital reached five times the level of the same period of the previous year and there was much more serious cases of H1N1 influenza.
It is reported that the current round of influenza virus advantage strain B (Yamagata), is a long-term latent for many years has not caused a pandemic influenza strains, it is also because of its quiet for a long time, the general population of this strain of immunity The basic lack of, causing the population lack of immune barrier. "The influenza vaccine component used in the South, which covers only two types of H1N1, H3N2 and B (Victoria) influenza A vaccines, does not cover the virus subtype B (Yamagata), which to some extent also caused the flu Large area popular. "
Last year, Guangzhou was the pandemic of pandemic influenza
Vaccine manufacturers are developing new vaccines to be covered
According to the CDC influenza surveillance system in Guangzhou, influenza-like viruses were detected in the sentinel samples of sentinel hospitals in Guangzhou in each of the months of 2017, showing A (H1N1) pmd09, A (H3N2) subtype and B (Victoria ) Type and B (Yamagata) type common cycle. Among them, two waves peaked in May-June and November-December, accounting for 65.29% of A (H3N2) subtype in the first half of the year and 53.19% in the second half of the year.
The current round of Yamagata influenza B virus also showed a slight variation (not easy to trigger panic mutations). Zhong Nanshan said that the virus shows the characteristics of people susceptible to infection, the duration will be slightly longer, but the vast majority are mainly mild, rarely causing severe cases or deaths.
"The current round of flu epidemic, I estimate, will come to an end by the end of the month, and against this subtype of influenza, our vaccine research and development agencies are stepping up research and development and production, I believe soon there will be coverage of this subtype Vaccine available "Zhong Nanshan said.
Know more about the flu virus
The coexistence of a large number of natural influenza viruses is also easy to mutation
The current epidemic of influenza virus, a very large number, mainly divided into A, B, C three types, while in our country is generally used to distinguish between A, B, C to. The pandemic in 2009 was Type A H1N1 flu, the type A H1N1 flu.
Zhong Nanshan said that the flu virus is actually very unstable, there may be a small drift of gene fragments, which is a virus mutation; there may be the entire conversion of the virus, which can be understood as a mutation. In this popular type B influenza, there has been some variation, making it more contagious.
The reason for the mutation of influenza virus is still not explained at present. Factors such as climate and environment can affect the virus mutation indirectly. At present, we can only predict the prevalence of the dominant virus strain in the short term according to the provisions of the World Health Organization and the research of global scientists in a period of three to four years, and then cover it with the method of polyvalent vaccine. prevention.
It is reported that on the basis of the monitoring results of the global influenza surveillance and response system, WHO annually proposes the vaccine components of the next popular season based on the major influenza pandemic strains of the previous year in the northern and southern hemispheres. For the next influenza season in the northern hemisphere, a suggestion will be given in February or March, while for the next pandemic in the southern hemisphere, a suggestion will be given in September.
Zhong Nanshan: This winter flu into the end of the new tetravalent vaccine is an emergency research and development
Taking the specific situation in our country as an example, at present, the flu vaccines that can be inoculated in our country include the following epidemic strains and belong to the recommended influenza vaccine recommended by the WHO for the 2017-2018 influenza season in the northern hemisphere:
- A / Michigan / 45/2015 (H1N1) pdm09 - like virus;
- A / Hong Kong / 4801/2014 (H3N2) - like virus;
- Type B / Brisbane / 60/2008-like virus;
Compared with the recommended strains of the 2016-2017 influenza season in the Northern Hemisphere, the strains of the recommended influenza A (H1N1) pmd09 strains in the northern hemisphere influenza in the 2017-2018 period have been changed. The type A / California / 7/2009 (H1N1) pdm09- like virus was replaced by type A / Michigan / 45/2015 (H1N1) pdm09-like virus.
Flu vaccine also hit?
Immediately enter the next influenza season? Key people still recommend vaccination
In addition to affecting the virus's climate variation, the epidemic also has a great impact on the flu. Such as the weather after the snow is colder, humidity increases, dust and other substances decreased. Fresh air at this time for the spread of influenza virus inhibition. However, on the other hand, after the snow is cold, there will be many crowds gathered in the house. Care should be taken to keep the air flowing smoothly.
Although influenza vaccine currently recommended on the market does not cover the current epidemic of influenza strains. But for vaccination, Zhong Nanshan still holds a positive attitude. "Vaccination is the most important way to prevent a pandemic of influenza, and in March, Guangzhou will enter the mainstream influenza A-high season again in March, just around the corner." Influenza A viruses are more likely to cause severe illness and death from post-infection clinical outcomes, so vaccination is necessary to reduce the risk of morbidity, serious illness and death in special populations.
...
Your position: Guangzhou Daily Ocean Network Home > News Channel > Community > Text
Zhong Nanshan: This winter flu into the end of the new tetravalent vaccine is an emergency research and development
2018-01-17 08:48 Source: South Network share it
Since late December last year, a flu has swept across the country. Influenced by the popularity of Type A Influenza in previous years, what is the fierce trend of Type B Influenza prevailing this year? What are the current epidemic characteristics of type B influenza? Flu vaccination there is no need for vaccination?
Zhong Nanshan, an academician of the Chinese Academy of Engineering, said in an interview with a reporter today that the current pandemic flu is of a type that has not yet been covered by the flu vaccine and that there is a slight change in the flu virus itself.
"The flu pandemic from the end of last year to early this year is now near the end of the period, and I believe it will be completed by the end of the month." The current vaccine research and development organization is urgently developing a new tetravalent vaccine that covers the epidemic type of influenza this winter, "said Dr. Zhong Nanshan.
Flu-like cases were more than double the same period last year
But far from the high prevalence of a stream in 2009
In this round of influenza epidemic, some media, especially since media coverage, compared this year's flu epidemic with the 2003 SARS and the 2009 influenza pandemic. According to the National Influenza sentinel hospital test results show that the current positive rate of influenza virus up to 40%, mainly B type. According to China CDC test data confirmed in recent weeks the national out-patient, emergency reported influenza virus than the same period the previous three years.
"So far, the number of influenza-like cases monitored by the hospital is more than double that of the same period of last year, and the predominant strain of pandemic is influenza type B. There are more patients infected, but very few cases of severe cases are caused," said Zhong Nanshan. It is less scientific to equate this winter's flu epidemic with SARS or the 2009 pandemic worldwide.
Zhong Nanshan: This winter flu into the end of the new tetravalent vaccine is an emergency research and development
In the 2009 influenza pandemic, the number of flu-like cases monitored by the hospital reached five times the level of the same period of the previous year and there was much more serious cases of H1N1 influenza.
It is reported that the current round of influenza virus advantage strain B (Yamagata), is a long-term latent for many years has not caused a pandemic influenza strains, it is also because of its quiet for a long time, the general population of this strain of immunity The basic lack of, causing the population lack of immune barrier. "The influenza vaccine component used in the South, which covers only two types of H1N1, H3N2 and B (Victoria) influenza A vaccines, does not cover the virus subtype B (Yamagata), which to some extent also caused the flu Large area popular. "
Last year, Guangzhou was the pandemic of pandemic influenza
Vaccine manufacturers are developing new vaccines to be covered
According to the CDC influenza surveillance system in Guangzhou, influenza-like viruses were detected in the sentinel samples of sentinel hospitals in Guangzhou in each of the months of 2017, showing A (H1N1) pmd09, A (H3N2) subtype and B (Victoria ) Type and B (Yamagata) type common cycle. Among them, two waves peaked in May-June and November-December, accounting for 65.29% of A (H3N2) subtype in the first half of the year and 53.19% in the second half of the year.
The current round of Yamagata influenza B virus also showed a slight variation (not easy to trigger panic mutations). Zhong Nanshan said that the virus shows the characteristics of people susceptible to infection, the duration will be slightly longer, but the vast majority are mainly mild, rarely causing severe cases or deaths.
"The current round of flu epidemic, I estimate, will come to an end by the end of the month, and against this subtype of influenza, our vaccine research and development agencies are stepping up research and development and production, I believe soon there will be coverage of this subtype Vaccine available "Zhong Nanshan said.
Know more about the flu virus
The coexistence of a large number of natural influenza viruses is also easy to mutation
The current epidemic of influenza virus, a very large number, mainly divided into A, B, C three types, while in our country is generally used to distinguish between A, B, C to. The pandemic in 2009 was Type A H1N1 flu, the type A H1N1 flu.
Zhong Nanshan said that the flu virus is actually very unstable, there may be a small drift of gene fragments, which is a virus mutation; there may be the entire conversion of the virus, which can be understood as a mutation. In this popular type B influenza, there has been some variation, making it more contagious.
The reason for the mutation of influenza virus is still not explained at present. Factors such as climate and environment can affect the virus mutation indirectly. At present, we can only predict the prevalence of the dominant virus strain in the short term according to the provisions of the World Health Organization and the research of global scientists in a period of three to four years, and then cover it with the method of polyvalent vaccine. prevention.
It is reported that on the basis of the monitoring results of the global influenza surveillance and response system, WHO annually proposes the vaccine components of the next popular season based on the major influenza pandemic strains of the previous year in the northern and southern hemispheres. For the next influenza season in the northern hemisphere, a suggestion will be given in February or March, while for the next pandemic in the southern hemisphere, a suggestion will be given in September.
Zhong Nanshan: This winter flu into the end of the new tetravalent vaccine is an emergency research and development
Taking the specific situation in our country as an example, at present, the flu vaccines that can be inoculated in our country include the following epidemic strains and belong to the recommended influenza vaccine recommended by the WHO for the 2017-2018 influenza season in the northern hemisphere:
- A / Michigan / 45/2015 (H1N1) pdm09 - like virus;
- A / Hong Kong / 4801/2014 (H3N2) - like virus;
- Type B / Brisbane / 60/2008-like virus;
Compared with the recommended strains of the 2016-2017 influenza season in the Northern Hemisphere, the strains of the recommended influenza A (H1N1) pmd09 strains in the northern hemisphere influenza in the 2017-2018 period have been changed. The type A / California / 7/2009 (H1N1) pdm09- like virus was replaced by type A / Michigan / 45/2015 (H1N1) pdm09-like virus.
Flu vaccine also hit?
Immediately enter the next influenza season? Key people still recommend vaccination
In addition to affecting the virus's climate variation, the epidemic also has a great impact on the flu. Such as the weather after the snow is colder, humidity increases, dust and other substances decreased. Fresh air at this time for the spread of influenza virus inhibition. However, on the other hand, after the snow is cold, there will be many crowds gathered in the house. Care should be taken to keep the air flowing smoothly.
Although influenza vaccine currently recommended on the market does not cover the current epidemic of influenza strains. But for vaccination, Zhong Nanshan still holds a positive attitude. "Vaccination is the most important way to prevent a pandemic of influenza, and in March, Guangzhou will enter the mainstream influenza A-high season again in March, just around the corner." Influenza A viruses are more likely to cause severe illness and death from post-infection clinical outcomes, so vaccination is necessary to reduce the risk of morbidity, serious illness and death in special populations.
...
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