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China NHFPC issued its first draft of its Zika prevention and control program on February 4, 2016
Provinces, autonomous regions and municipalities Health and Family Planning Commission, the Xinjiang Production and Construction Corps Health Bureau, Chinese Center for Disease Control and Prevention:
Since 2014, the Inter-American countries occurred in many countries and regions Zika virus infection, Europe, Asia, Oceania and other places also entered a case report. Recently, Brazil outbreaks Zika virus outbreak. For the good of the country that may arise Zika virus disease prevention and control preparation, our commission formulated the "Zika virus disease prevention and control program (first edition)" (available from the National Health and Family Planning Commission website www.nhfpc.gov.cn download). Is issued to you, please refer to execution. Accessories: Zika virus disease prevention and control program (first edition)
National Health and Family Planning Commission Office of the
February 3, 2016 annex
Zika virus (Zika Virus Disease) is caused by Zika virus (Zika Virus) and a self-limiting acute illness spread by the mosquito-borne. Zika virus in 1947 for the first time from a rhesus monkey was discovered in Uganda in 1952 isolated in Uganda and Tanzania humans. Prior to 2007, only 14 cases of the Global Reporting Zika virus sporadic cases in 2007 for the first time in the Pacific island nation of Micronesia Yap Island found Zika virus outbreak, later found Zika virus infections and outbreaks of countries and regions have increased. May 2015, Brazil reported the first case of Zika virus disease cases, as at the end of January 2016, Brazil and other 24 countries and regions, the Americas reporting of local infections. At the same time, many countries report Europe, North America and other places of discovery imported cases, China's Taiwan also reported one case of imported cases from Thailand. When Zika virus outbreak, Brazil and other countries neonatal microcephaly significant increase in the number of cases, the existing evidence suggests that neonatal microcephaly may Zika virus infection in pregnant women. Rapid spread of the epidemic and the possible causal relationship between microcephaly and caused widespread concern in the international community.
Zika virus transmissible presence in Southern China Aedes media in recent years, with a similar mode of transmission of imported dengue epidemic continues to increase, and in the southern part of the province caused a large-scale outbreak. As with the relevant country or region increasingly close personnel exchanges, the existence of the risk of input Zika virus. Especially in summer and autumn in southern China Aedes higher density, there are cases when the input does not exclude the possibility of the spread of local transmission occurred in the local area. Guidance prevention and control work to do around the Zika virus disease prevention and control program is formulated. I. Disease Overview (a) etiology. Zika virus belongs to the Flaviviridae family (Flaviviridae) Flavivirus (Flavivirus), spherical diameter of about 40-70nm, it enveloped. Genome is a single positive-strand RNA, a length of about 10.8Kb, divided into two Asian and African-type genotype, present in South America for the Asian epidemic virus type. There is a strong serological cross-reactivity with the Zika virus and flaviviruses dengue virus, yellow fever and West Nile virus and other viruses. Virus in mosquito-derived cells (C6 / 36), mammalian cells (Vero) cells in culture, etc. multiply and produce disease. Zika virus resistance is unknown, but flavivirus virus is generally not acid, not heat, 60 ℃ 30 minutes to inactivate 70% ethanol, 1% sodium hypochlorite, lipid solvents, peracetic acid disinfectants and ultraviolet irradiation It can be inactivated. (B) epidemiology. 1. And transmission media (1) the source of infection: non-human primates in patients with latent infection and infection Zika virus is likely the source of infection of the disease. (2) Media: Aedes aegypti is the major media Zika virus, Aedes albopictus, Aedes Africa, yellow head and other Aedes albopictus mosquitoes can transmit the virus. According to the monitoring, and dissemination of the Aedes species Zika virus related mainly Aedes aegypti and Aedes albopictus, Aedes aegypti which is mainly distributed in Hainan Province, Leizhou Peninsula, Guangdong and Yunnan Xishuangbanna, Dehong, temporary Cang City and other areas; Aedes albopictus is widely distributed in the south of the vast region of Hebei, Shanxi, Shaanxi. 2. Transmission (1) for the mosquito-borne virus Zika main route of transmission. Mosquito bites Zika were infected with HIV, which then bites by way of transmitting the virus to others. (2) spread between people. MTCT: from placenta of pregnant women had Zika virus was detected, suggesting that Zika virus can be transmitted through the placenta from mother to fetus.In addition, Zika viremia pregnant women, may spread to the newborn in the delivery process in the Walled card virus. It has been detected in breast milk Zika virus nucleic acid, but there is no report Zika virus through breast-feeding infected newborns. Blood-borne and sexually transmitted: Zika virus may be spread through blood transfusion or sexual contact. Up to now, each report cases of transfusion-transmitted and can spread through sexual contact. 3. Population susceptibility of various groups, including pregnant women are generally susceptible to Zika virus. Zika virus had infected people may have immunity against re-infection. 4. Incubation period and infectious period (1) Incubation period: the incubation period of the disease is currently unclear, limited data suggest possible 3 to 12 days. (2) contagious: infection in patients is not known, studies have shown that patients with early viremia, and contagious. 5. Geographical distribution Zika virus disease is currently prevalent in the Americas, Africa, Southeast Asia and the Pacific island countries and other countries and regions. (1) Prior to 2014 the regional distribution from 1947 to 2007 virus was discovered before, Zika virus mainly distributed in confirmed cases of human infection with only 14 cases. April-July 2007, the Pacific Islands Micronesia Yap Island 185 patients appear fever, headache, rash, conjunctivitis and joint pain and other symptoms, 49 patients were diagnosed as Zika virus infection, or severe deaths. After several years, Thailand, Cambodia, Indonesia and New Caledonia Southeast Asia there have been sporadic cases reported. 2013 --2014, located in the South Pacific, French Polynesia Zika virus outbreak occurred, about 10,000 cases of reported cases, 70 cases of severe cases, including neurological disorders (Guillain - Barre syndrome, meningoencephalitis) or autoimmune disorders (thrombocytopenic purpura, leukopenia) complications. (2) Since 2015 the regional distribution in May 2015, Brazil reported the first case of Zika virus infections diagnosed, as of the end of January 2016, America has 24 countries and regions have local report Zika virus infections, including: Colombia, Brazil, Bolivia, Barbados, Curacao, Dominica, Ecuador, El Salvador, French Guiana, Guadeloupe, Guatemala, Guyana, Honduras, Mexico, Martinique, Nicaragua, Haiti, St. Maarten, Puerto Rico , Paraguay, Panama, Suriname, United States Virgin Islands, Venezuela. Since 2015, the United States, Canada, Asia, China Taiwan, Europe, Denmark, Finland, Germany, Italy, Portugal, the Netherlands, Spain, Sweden, United Kingdom, Switzerland and other countries and regions in North America, Zika virus were found in imported cases. China's mainland and Hong Kong and Macao has no Zika virus disease cases reported. 6. Seasonal incidence Features incidence of the season with local media Aedes seasonal fluctuation related to the peak epidemic appears more in the summer and autumn. In tropical and subtropical regions, Zika virus disease all year round. (Iii) clinical manifestations. Clinical symptoms include fever, rash (mostly rash), joint pain, muscle pain, conjunctivitis. Zika virus infection, about 80% of human latent infection, only 20% of the above clinical symptoms usually last 2-7 days after healing, severe cases and deaths are rare. Zika virus infection may cause a few people nervous system and autoimmune complications after infection in pregnant women may lead to neonatal microcephaly. Second, the diagnosis, treatment and reporting (a) diagnosis. Various medical institutions at all levels should follow "Zika virus disease treatment program" to do diagnostic work-related cases. Diagnosis should pay attention and dengue, chikungunya and other diseases were identified. The first case of Zika virus infections diagnosed provinces discovered by the China Disease Prevention and Control Center detected after laboratory confirmation review. Severe cases, deaths and the index case and the first outbreak of cases should be sent to the Chinese specimens Disease Prevention and Control Center laboratory for review testing. (II). Various medical institutions at all levels found Zika virus suspected cases, when clinically diagnosed cases or confirmed cases should be carried out within 24 hours of direct network packets through national disease surveillance information report management system, report disease category selection "in other infectious diseases Zika virus diseases "such as imported cases in the remarks column shall indicate the source region, a unified format for the" outside input / X Region "or" domestic input / X X X City Province county. " First case appears (district) within the county, according to provisional public health emergencies requires planning at the county level health administrative departments within two hours, and at the same time by the public health emergency management information reporting system for network reporting. Received reports of health planning administrative department shall, within two hours of the people's government at a higher level of health planning and administration department. (Iii) treatment. The disease is usually self-limiting disease, there is no specific antiviral drugs for the disease, patients are taken to symptomatic treatment.Third, the laboratory testing in accordance with the "Zika virus laboratory technology program" (Appendix 1) cases and mosquito-borne specimen collection, packaging, transport and laboratory testing. Zika virus detection methods include viral nucleic acid detection, IgM antibody detection, virus neutralizing antibody detection and separation. Zika virus and other flaviviruses virus has a strong serological cross-reactivity, mainly the use of viral nucleic acid detection. Carrying out mosquito-borne Zika virus detection, to capture adult mosquitoes or larvae of Aedes virus nucleic acid detection. Zika virus in our country belong to three categories of pathogens should be two biosafety laboratory (BSL-2) to carry out laboratory testing. Shall be in accordance with the relevant provisions. "Pathogenic microbiology laboratory bio-safety regulations" requirements, good bio-security work. Fourth, the epidemiological investigation of disease prevention and control institutions in the case after receiving the report, should immediately organize professional investigation, analysis the source of infection, search for suspicious cases, to assess the risk of further infection and epidemic. Find local infection cases, active search for cases should be carried out as well as mosquito-borne emergency monitoring, analysis of the epidemic dynamics, assessment of trends, the timely submission of targeted control measures. An indication of all cases of sporadic cases and outbreaks, the first cases of severe, deaths, and because the survey to identify the nature of the epidemic and the need to spread the range determined, in accordance with "cases of Zika virus disease epidemiology questionnaire" ( Appendix 2) a detailed case-studies.Subsequent cases have occurred after the epidemic can be used to determine the nature of "Zika virus disease Household Survey Registration Form" (Appendix 3) collect epidemiological information brief.Fifth, prevention and control measures (a) prevent inputs. 1. Follow international epidemic dynamic progress closely tracking the international epidemic information Zika virus, a dynamic risk assessment, provide the basis for the formulation and adjustment of local prevention strategies and measures. 2. Needed issued a travel health tips to assist local health planning departments diplomatic, business, travel and entry-exit inspection and quarantine departments to go to Zika education and health tips for travelers and endemic areas virus overseas Chinese citizens. 3. Do a good job at frontier health and quarantine departments once found suspected cases should be promptly informed of the health department of health, the common good outbreak investigation and disposal. (Ii) monitoring and case management. 1. Case surveillance and early detection of various medical institutions at all levels found fever, rash, muscle and joint pain, patients should pay attention to understand the history of (popular area travel history) epidemiology of patients, the disease may be considered, and timely sampling inspection. In addition, neonatal microcephaly maternal, if suspicious epidemiological history, but also need to consider the Zika virus infection. 2. Epidemiological investigation of cases related to case investigation, focusing on the history of investigative activities two weeks before the onset of symptoms, to identify suspected infection site, looking for the source of infection; while investigating the activities of the week after the onset of the history, to carry out searches of cases to assess the occurrence and prevalence of infection risk. 3. Case search for imported cases should be traced in detail travel history, the focus in the search for common travel with their staff. As to immigration cases from one week after onset was in the county (district) activities, should also search for suspected cases in their living and working area. In the event of sporadic cases of local infection, with cases of or adjacent to the residence of several families, workplaces and other cases as the center of activities, the scope of activities delineated Aedes reference within a radius of 200 meters of space in the range of the core area, and 1 case of infection It may designate more than one core area, core area in search of cases. According to a different town or village building types, suggesting that the scope of Aedes activities appropriate to expand or narrow your search radius. 4. Case management of acute isolation of patients must take anti-mosquito measures, mosquito isolation period from the date of the onset of less than 7 days, and should continue until the fever subsided. Severe cases should be hospitalized. Health personnel in the conduct of medical and epidemiological investigation should take standard precautions. In doing case management and general hospital infection control measures on the basis of medical institutions should implement mosquito control measures to prevent nosocomial transmission. (C) vector surveillance and control. There are media distribution area, in addition to doing the above work, the need to do media monitoring and control. 1.Daily monitoring and control of health administrative departments at all levels responsible for planning and leading local disease prevention and control organizations to carry out community-based mosquito density monitoring, including the Aedes species, density, and other seasonal fluctuation. Daily monitoring of the scope, methods and frequency requirements with dengue fever, may refer to "dengue vector Aedes surveillance guidelines" in the routine monitoring conducted. When they find an intermediary Breteau index Aedes mosquito oviposition and indices of more than 20, should be submitted to local government organizations patriotic public health campaign, removal of indoor and outdoor media Aedes mosquito breeding sites and to carry out preventive campaigns to reduce Aedes density to reduce or eliminate the risk of mosquito-borne disease outbreaks Zika virus disease. 2. Monitoring and emergency control inputs or found locally contracted cases of Zika virus activity in mosquito season, should start emergency monitoring. Aedes emergency monitoring regional media, methods and frequency requirements with dengue fever, may refer to "dengue vector Aedes surveillance guidelines" in the emergency monitoring carried out. When there are cases of Zika virus outbreaks for the center and to 200 meters radius内布雷Chart Index or mosquito oviposition index ≥5, precautionary area (outside the core area of exhibition 200 m radius) ≥10 or when Breteau when the mosquito oviposition index or indices greater than 20, you should start the emergency control of Aedes media. Media Aedes emergency control points include: do community mobilization, patriotic public health campaign, do a good job cleaning up mosquito breeding sites; educate the masses do personal protection; take precise emergency outbreaks kill adult mosquitoes, etc., through the integrated media Aedes control measures, as soon as the Breteau index or indices mosquito oviposition controlled at 5 or less. (Iv) advocacy and communication. The presence of pandemic risk areas should take a variety of effective forms, user-friendly way to carry out health education activities. Publicity Highlights include: Zika virus by the Aedes (commonly known as piebald mosquito or spend mosquito) bites; Aedes breeding in water tanks, basins, tires, flower pots, vases and other water containers; removing stagnant water, turn pots pouring, eliminate mosquito breeding sites can prevent Zika virus epidemic; wear long-sleeved clothes in outbreak areas, the exposed parts of the body smear mosquito water, insect repellent or mosquito nets, mosquito nets to prevent mosquito bites. In addition to general travel health tips, the program should remind pregnant women and pregnant women with caution to the Zika virus endemic countries or regions, such as when you do need to go to these countries or regions should be strictly proper personal protective measures to prevent mosquito bites. If you suspect may be infected Zika virus, should seek immediate medical attention, active travel history report, and receive medical follow-up. (V) training and laboratory capacity building. 1. Strengthen the training of medical personnel, improve the ability to identify disease diagnosis and treatment of medical personnel to carry out knowledge training, improve disease diagnosis and identification capabilities. Key areas to be popular every year before the season, combined with dengue, grassroots medical personnel to carry out intensive training Zika virus-related knowledge chikungunya prevention and control, and enhance awareness of the disease Zika virus, timely detection and reporting of suspected Walled card viral infections. 2. Establish Zika virus detection capabilities to establish and gradually extended laboratory technology Zika virus. The provincial Center for Disease Control and Prevention to establish as soon as possible the relevant laboratory testing techniques and methods, good laboratory techniques and reagents reserves gradually increase grassroots Centers for Disease Control and Prevention of the disease laboratory capacity to respond to outbreaks that may occur . Annex: 1. Zika virus laboratory technology program .docx
machine translation
National Health Council on Family Planning Commission issued Zika virus disease prevention and control program (first edition) notice
National Health and Family Planning Commission People's Republic of China2016-02-04
AXA Power invention No. 4 [2016]
Provinces, autonomous regions and municipalities Health and Family Planning Commission, the Xinjiang Production and Construction Corps Health Bureau, Chinese Center for Disease Control and Prevention:
Since 2014, the Inter-American countries occurred in many countries and regions Zika virus infection, Europe, Asia, Oceania and other places also entered a case report. Recently, Brazil outbreaks Zika virus outbreak. For the good of the country that may arise Zika virus disease prevention and control preparation, our commission formulated the "Zika virus disease prevention and control program (first edition)" (available from the National Health and Family Planning Commission website www.nhfpc.gov.cn download). Is issued to you, please refer to execution. Accessories: Zika virus disease prevention and control program (first edition)
National Health and Family Planning Commission Office of the
February 3, 2016
Zika virus disease prevention and control program
(first edition)
(first edition)
Zika virus (Zika Virus Disease) is caused by Zika virus (Zika Virus) and a self-limiting acute illness spread by the mosquito-borne. Zika virus in 1947 for the first time from a rhesus monkey was discovered in Uganda in 1952 isolated in Uganda and Tanzania humans. Prior to 2007, only 14 cases of the Global Reporting Zika virus sporadic cases in 2007 for the first time in the Pacific island nation of Micronesia Yap Island found Zika virus outbreak, later found Zika virus infections and outbreaks of countries and regions have increased. May 2015, Brazil reported the first case of Zika virus disease cases, as at the end of January 2016, Brazil and other 24 countries and regions, the Americas reporting of local infections. At the same time, many countries report Europe, North America and other places of discovery imported cases, China's Taiwan also reported one case of imported cases from Thailand. When Zika virus outbreak, Brazil and other countries neonatal microcephaly significant increase in the number of cases, the existing evidence suggests that neonatal microcephaly may Zika virus infection in pregnant women. Rapid spread of the epidemic and the possible causal relationship between microcephaly and caused widespread concern in the international community.
Zika virus transmissible presence in Southern China Aedes media in recent years, with a similar mode of transmission of imported dengue epidemic continues to increase, and in the southern part of the province caused a large-scale outbreak. As with the relevant country or region increasingly close personnel exchanges, the existence of the risk of input Zika virus. Especially in summer and autumn in southern China Aedes higher density, there are cases when the input does not exclude the possibility of the spread of local transmission occurred in the local area. Guidance prevention and control work to do around the Zika virus disease prevention and control program is formulated. I. Disease Overview (a) etiology. Zika virus belongs to the Flaviviridae family (Flaviviridae) Flavivirus (Flavivirus), spherical diameter of about 40-70nm, it enveloped. Genome is a single positive-strand RNA, a length of about 10.8Kb, divided into two Asian and African-type genotype, present in South America for the Asian epidemic virus type. There is a strong serological cross-reactivity with the Zika virus and flaviviruses dengue virus, yellow fever and West Nile virus and other viruses. Virus in mosquito-derived cells (C6 / 36), mammalian cells (Vero) cells in culture, etc. multiply and produce disease. Zika virus resistance is unknown, but flavivirus virus is generally not acid, not heat, 60 ℃ 30 minutes to inactivate 70% ethanol, 1% sodium hypochlorite, lipid solvents, peracetic acid disinfectants and ultraviolet irradiation It can be inactivated. (B) epidemiology. 1. And transmission media (1) the source of infection: non-human primates in patients with latent infection and infection Zika virus is likely the source of infection of the disease. (2) Media: Aedes aegypti is the major media Zika virus, Aedes albopictus, Aedes Africa, yellow head and other Aedes albopictus mosquitoes can transmit the virus. According to the monitoring, and dissemination of the Aedes species Zika virus related mainly Aedes aegypti and Aedes albopictus, Aedes aegypti which is mainly distributed in Hainan Province, Leizhou Peninsula, Guangdong and Yunnan Xishuangbanna, Dehong, temporary Cang City and other areas; Aedes albopictus is widely distributed in the south of the vast region of Hebei, Shanxi, Shaanxi. 2. Transmission (1) for the mosquito-borne virus Zika main route of transmission. Mosquito bites Zika were infected with HIV, which then bites by way of transmitting the virus to others. (2) spread between people. MTCT: from placenta of pregnant women had Zika virus was detected, suggesting that Zika virus can be transmitted through the placenta from mother to fetus.In addition, Zika viremia pregnant women, may spread to the newborn in the delivery process in the Walled card virus. It has been detected in breast milk Zika virus nucleic acid, but there is no report Zika virus through breast-feeding infected newborns. Blood-borne and sexually transmitted: Zika virus may be spread through blood transfusion or sexual contact. Up to now, each report cases of transfusion-transmitted and can spread through sexual contact. 3. Population susceptibility of various groups, including pregnant women are generally susceptible to Zika virus. Zika virus had infected people may have immunity against re-infection. 4. Incubation period and infectious period (1) Incubation period: the incubation period of the disease is currently unclear, limited data suggest possible 3 to 12 days. (2) contagious: infection in patients is not known, studies have shown that patients with early viremia, and contagious. 5. Geographical distribution Zika virus disease is currently prevalent in the Americas, Africa, Southeast Asia and the Pacific island countries and other countries and regions. (1) Prior to 2014 the regional distribution from 1947 to 2007 virus was discovered before, Zika virus mainly distributed in confirmed cases of human infection with only 14 cases. April-July 2007, the Pacific Islands Micronesia Yap Island 185 patients appear fever, headache, rash, conjunctivitis and joint pain and other symptoms, 49 patients were diagnosed as Zika virus infection, or severe deaths. After several years, Thailand, Cambodia, Indonesia and New Caledonia Southeast Asia there have been sporadic cases reported. 2013 --2014, located in the South Pacific, French Polynesia Zika virus outbreak occurred, about 10,000 cases of reported cases, 70 cases of severe cases, including neurological disorders (Guillain - Barre syndrome, meningoencephalitis) or autoimmune disorders (thrombocytopenic purpura, leukopenia) complications. (2) Since 2015 the regional distribution in May 2015, Brazil reported the first case of Zika virus infections diagnosed, as of the end of January 2016, America has 24 countries and regions have local report Zika virus infections, including: Colombia, Brazil, Bolivia, Barbados, Curacao, Dominica, Ecuador, El Salvador, French Guiana, Guadeloupe, Guatemala, Guyana, Honduras, Mexico, Martinique, Nicaragua, Haiti, St. Maarten, Puerto Rico , Paraguay, Panama, Suriname, United States Virgin Islands, Venezuela. Since 2015, the United States, Canada, Asia, China Taiwan, Europe, Denmark, Finland, Germany, Italy, Portugal, the Netherlands, Spain, Sweden, United Kingdom, Switzerland and other countries and regions in North America, Zika virus were found in imported cases. China's mainland and Hong Kong and Macao has no Zika virus disease cases reported. 6. Seasonal incidence Features incidence of the season with local media Aedes seasonal fluctuation related to the peak epidemic appears more in the summer and autumn. In tropical and subtropical regions, Zika virus disease all year round. (Iii) clinical manifestations. Clinical symptoms include fever, rash (mostly rash), joint pain, muscle pain, conjunctivitis. Zika virus infection, about 80% of human latent infection, only 20% of the above clinical symptoms usually last 2-7 days after healing, severe cases and deaths are rare. Zika virus infection may cause a few people nervous system and autoimmune complications after infection in pregnant women may lead to neonatal microcephaly. Second, the diagnosis, treatment and reporting (a) diagnosis. Various medical institutions at all levels should follow "Zika virus disease treatment program" to do diagnostic work-related cases. Diagnosis should pay attention and dengue, chikungunya and other diseases were identified. The first case of Zika virus infections diagnosed provinces discovered by the China Disease Prevention and Control Center detected after laboratory confirmation review. Severe cases, deaths and the index case and the first outbreak of cases should be sent to the Chinese specimens Disease Prevention and Control Center laboratory for review testing. (II). Various medical institutions at all levels found Zika virus suspected cases, when clinically diagnosed cases or confirmed cases should be carried out within 24 hours of direct network packets through national disease surveillance information report management system, report disease category selection "in other infectious diseases Zika virus diseases "such as imported cases in the remarks column shall indicate the source region, a unified format for the" outside input / X Region "or" domestic input / X X X City Province county. " First case appears (district) within the county, according to provisional public health emergencies requires planning at the county level health administrative departments within two hours, and at the same time by the public health emergency management information reporting system for network reporting. Received reports of health planning administrative department shall, within two hours of the people's government at a higher level of health planning and administration department. (Iii) treatment. The disease is usually self-limiting disease, there is no specific antiviral drugs for the disease, patients are taken to symptomatic treatment.Third, the laboratory testing in accordance with the "Zika virus laboratory technology program" (Appendix 1) cases and mosquito-borne specimen collection, packaging, transport and laboratory testing. Zika virus detection methods include viral nucleic acid detection, IgM antibody detection, virus neutralizing antibody detection and separation. Zika virus and other flaviviruses virus has a strong serological cross-reactivity, mainly the use of viral nucleic acid detection. Carrying out mosquito-borne Zika virus detection, to capture adult mosquitoes or larvae of Aedes virus nucleic acid detection. Zika virus in our country belong to three categories of pathogens should be two biosafety laboratory (BSL-2) to carry out laboratory testing. Shall be in accordance with the relevant provisions. "Pathogenic microbiology laboratory bio-safety regulations" requirements, good bio-security work. Fourth, the epidemiological investigation of disease prevention and control institutions in the case after receiving the report, should immediately organize professional investigation, analysis the source of infection, search for suspicious cases, to assess the risk of further infection and epidemic. Find local infection cases, active search for cases should be carried out as well as mosquito-borne emergency monitoring, analysis of the epidemic dynamics, assessment of trends, the timely submission of targeted control measures. An indication of all cases of sporadic cases and outbreaks, the first cases of severe, deaths, and because the survey to identify the nature of the epidemic and the need to spread the range determined, in accordance with "cases of Zika virus disease epidemiology questionnaire" ( Appendix 2) a detailed case-studies.Subsequent cases have occurred after the epidemic can be used to determine the nature of "Zika virus disease Household Survey Registration Form" (Appendix 3) collect epidemiological information brief.Fifth, prevention and control measures (a) prevent inputs. 1. Follow international epidemic dynamic progress closely tracking the international epidemic information Zika virus, a dynamic risk assessment, provide the basis for the formulation and adjustment of local prevention strategies and measures. 2. Needed issued a travel health tips to assist local health planning departments diplomatic, business, travel and entry-exit inspection and quarantine departments to go to Zika education and health tips for travelers and endemic areas virus overseas Chinese citizens. 3. Do a good job at frontier health and quarantine departments once found suspected cases should be promptly informed of the health department of health, the common good outbreak investigation and disposal. (Ii) monitoring and case management. 1. Case surveillance and early detection of various medical institutions at all levels found fever, rash, muscle and joint pain, patients should pay attention to understand the history of (popular area travel history) epidemiology of patients, the disease may be considered, and timely sampling inspection. In addition, neonatal microcephaly maternal, if suspicious epidemiological history, but also need to consider the Zika virus infection. 2. Epidemiological investigation of cases related to case investigation, focusing on the history of investigative activities two weeks before the onset of symptoms, to identify suspected infection site, looking for the source of infection; while investigating the activities of the week after the onset of the history, to carry out searches of cases to assess the occurrence and prevalence of infection risk. 3. Case search for imported cases should be traced in detail travel history, the focus in the search for common travel with their staff. As to immigration cases from one week after onset was in the county (district) activities, should also search for suspected cases in their living and working area. In the event of sporadic cases of local infection, with cases of or adjacent to the residence of several families, workplaces and other cases as the center of activities, the scope of activities delineated Aedes reference within a radius of 200 meters of space in the range of the core area, and 1 case of infection It may designate more than one core area, core area in search of cases. According to a different town or village building types, suggesting that the scope of Aedes activities appropriate to expand or narrow your search radius. 4. Case management of acute isolation of patients must take anti-mosquito measures, mosquito isolation period from the date of the onset of less than 7 days, and should continue until the fever subsided. Severe cases should be hospitalized. Health personnel in the conduct of medical and epidemiological investigation should take standard precautions. In doing case management and general hospital infection control measures on the basis of medical institutions should implement mosquito control measures to prevent nosocomial transmission. (C) vector surveillance and control. There are media distribution area, in addition to doing the above work, the need to do media monitoring and control. 1.Daily monitoring and control of health administrative departments at all levels responsible for planning and leading local disease prevention and control organizations to carry out community-based mosquito density monitoring, including the Aedes species, density, and other seasonal fluctuation. Daily monitoring of the scope, methods and frequency requirements with dengue fever, may refer to "dengue vector Aedes surveillance guidelines" in the routine monitoring conducted. When they find an intermediary Breteau index Aedes mosquito oviposition and indices of more than 20, should be submitted to local government organizations patriotic public health campaign, removal of indoor and outdoor media Aedes mosquito breeding sites and to carry out preventive campaigns to reduce Aedes density to reduce or eliminate the risk of mosquito-borne disease outbreaks Zika virus disease. 2. Monitoring and emergency control inputs or found locally contracted cases of Zika virus activity in mosquito season, should start emergency monitoring. Aedes emergency monitoring regional media, methods and frequency requirements with dengue fever, may refer to "dengue vector Aedes surveillance guidelines" in the emergency monitoring carried out. When there are cases of Zika virus outbreaks for the center and to 200 meters radius内布雷Chart Index or mosquito oviposition index ≥5, precautionary area (outside the core area of exhibition 200 m radius) ≥10 or when Breteau when the mosquito oviposition index or indices greater than 20, you should start the emergency control of Aedes media. Media Aedes emergency control points include: do community mobilization, patriotic public health campaign, do a good job cleaning up mosquito breeding sites; educate the masses do personal protection; take precise emergency outbreaks kill adult mosquitoes, etc., through the integrated media Aedes control measures, as soon as the Breteau index or indices mosquito oviposition controlled at 5 or less. (Iv) advocacy and communication. The presence of pandemic risk areas should take a variety of effective forms, user-friendly way to carry out health education activities. Publicity Highlights include: Zika virus by the Aedes (commonly known as piebald mosquito or spend mosquito) bites; Aedes breeding in water tanks, basins, tires, flower pots, vases and other water containers; removing stagnant water, turn pots pouring, eliminate mosquito breeding sites can prevent Zika virus epidemic; wear long-sleeved clothes in outbreak areas, the exposed parts of the body smear mosquito water, insect repellent or mosquito nets, mosquito nets to prevent mosquito bites. In addition to general travel health tips, the program should remind pregnant women and pregnant women with caution to the Zika virus endemic countries or regions, such as when you do need to go to these countries or regions should be strictly proper personal protective measures to prevent mosquito bites. If you suspect may be infected Zika virus, should seek immediate medical attention, active travel history report, and receive medical follow-up. (V) training and laboratory capacity building. 1. Strengthen the training of medical personnel, improve the ability to identify disease diagnosis and treatment of medical personnel to carry out knowledge training, improve disease diagnosis and identification capabilities. Key areas to be popular every year before the season, combined with dengue, grassroots medical personnel to carry out intensive training Zika virus-related knowledge chikungunya prevention and control, and enhance awareness of the disease Zika virus, timely detection and reporting of suspected Walled card viral infections. 2. Establish Zika virus detection capabilities to establish and gradually extended laboratory technology Zika virus. The provincial Center for Disease Control and Prevention to establish as soon as possible the relevant laboratory testing techniques and methods, good laboratory techniques and reagents reserves gradually increase grassroots Centers for Disease Control and Prevention of the disease laboratory capacity to respond to outbreaks that may occur . Annex: 1. Zika virus laboratory technology program .docx
machine translation