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  • Harbin Veterinary Research Institute

    http://www.sina.com.cn 2008年07月18日05:00 Harbin Daily

    Harbin News Network's (ZHANG Xiao-peng Ho's beautiful), as China's earliest establishment of the Veterinary Research Institute, Chinese Academy of Agricultural Sciences in Harbin Veterinary Research Institute held yesterday to mark the 60th anniversary of the establishment of the General Assembly. The General Assembly read out the CPPCC National Committee Vice-Chairman of the Central United Front Work Department of Du Qinglin to the Kazakhstan Institute of the beast inscription. Provincial CPC Committee and deputy secretary and governor Li war on speech. Gao Hongbin, deputy minister of the Ministry of Agriculture, president of the Chinese Academy of Agricultural Sciences Hu-Qu Zhai, secretary of the party group Xue Liang, provincial and municipal Du Yu new leadership, Shen Liguo, LU Wei-feng, Hai-Sheng Liu, Li Xirong, Wang Tieqiang, Chun Tang, attended the meeting.

    Li war in his speech on behalf of the provincial party committee and government to Kazakhstan beast Institute congratulated the 60th anniversary of the founding. He said that through the unremitting efforts of several generations of people, animals and Kazakhstan Institute has evolved into a modern, strong, strong research and development capabilities, the international influence of the big national veterinary research institutions, training a number of renowned domestic and foreign experts , In many frontier areas achieved a major breakthrough, and access to important scientific research achievements, the country of Heilongjiang Province and major animal disease prevention and control work has made outstanding contributions to national and local have created tremendous economic and social benefits.

    Li pointed out that the war, the biological industry in Heilongjiang Province has been included in the strategic readjustment of the industrial structure in the industry. Hope that the Kazakhstan Institute rooted beast Longjiang this hot land for, give play to its advantages, the release of potential to further strengthen cooperation with local, veterinary biotechnology industry to accelerate development of Heilongjiang Province and China's economic and social development of better and faster to make new and greater contributions.

    According to reports, Kazakhstan beast Institute was founded in June 1, 1948, a total of 60 to 298 various types of scientific and technological achievements, of which five countries Invention Award, the National Science and Technology Progress Award 8, the National Conference on Science Award 6, More than 50 items of scientific research results reached the international advanced level. Kazakhstan beast Institute has also developed over 140 kinds of diagnostic reagents and vaccines directly applied to preventing and controlling animal diseases. In the Chinese Academy of Engineering of China in the 20th century major projects and technological achievements Award, the National Animal Medicine by Joseph Stalin in four major areas of success, equine infectious anemia disease donkey leukocyte attenuated vaccines, attenuated vaccine of classical swine fever in rabbits, sheep and rinderpest Goat of the attenuated vaccine, cattle lung disease in rabbits and attenuated vaccines, animal research and Kazakhstan are chaired or participated in the development. Kazakhstan by the use of animal research results, China's successful eradication of rinderpest, cattle lung disease, equine infectious anemia control the disease, the protection of millions of horses, donkeys, mules, as China's national defense and agricultural development has made outstanding contributions. At the same time, Kazakhstan beast of the academic research on the virus broke through the slow immunization theory, since in the international academic community still独领风骚.

    After the SARS outbreak, as the projects involved in SARS vaccine development unit, one of the Kazakhstan Institute beast through painstaking research, and finally completed a SARS vaccine in animal experiments; bird flu outbreak, the Kazakhstan Institute reserves beast on the 20 bird flu prevention and control technology Play an important role in the country have provided the H5N2, H5N1, H5 subtype of avian flu recombinant fowlpox vector live vaccine and new types of H5 subtype of avian influenza - the reorganization of the Newcastle disease live vaccine, such as the world's leading level of new bird flu vaccine And control techniques, and the disease diagnosed, monitoring, analysis and other aspects of government policy to provide a timely, accurate, detailed and accurate scientific basis, to become effective in preventing large-scale epidemic outbreak of the important technical support.

  • #2
    Re: Harbin Veterinary Research Institute

    "H5 subtype of avian flu recombinant fowlpox vector live vaccine"

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    • #3
      Re: Harbin Veterinary Research Institute

      <table align="center" border="0" cellpadding="0" cellspacing="0" width="95&#37;"><tbody><tr><td align="left" height="50" valign="top" width="100%">Qiao CL, Yu KZ, Jiang YP,et al.

      Protection of chickens against highly lethal H5N1 and H7N1 avian influenza viruses with a recombinant fowlpox virus co-expressing H5 haemagglutinin and N1 neuraminidase genes .

      Avian Pathology. 2003(32): 25-31.
      </td> </tr> <tr> <td align="left">
      Protection of chickens against highly lethal H5N1 and H7N1 avian influenza viruses with a recombinant fowlpox virus co-expressing H5 haemagglutinin and N1 neuraminidase genes
      <o:p></o:p>
      <o:p> </o:p>
      Qiao CL, Yu KZ, Jiang YP, Jia YQ, Tian GB, Liu M, Deng GH, Wang XR, Meng QW, Tang XY.

      <o:p></o:p>
      <o:p></o:p>
      Abstract:

      Inactivated whole avian influenza virus (AIV) vaccine provides protection against homologous haemagglutinin (HA) subtype virus, but poor protection against a heterologous HA virus. Moreover, it induces chickens to produce antibodies to cross-reactive antigens, especially nucleoprotein, which is limits AIV serological surveillance. In this study, a recombinant fowlpox virus co-expressing HA (H5 subtype) and NA (NI subtype)genes of AIV was evaluated for its ability to protect chickens against intramuscular challenge with a lethal dose of highly pathogenic (HP) AIV. Susceptible chickens were also vaccinated by wing-web puncture with the parent fowlpox vaccine virus. Following challenge 4 weeks later with HPAIV, all chickens vaccinated with recombinant virus were protected, while the chickens vaccinated with either the unaltered parent fowlpox vaccine virus or unvaccinated controls experienced 100% mortality following challenge. This protection was accompanied by the high levels of specific antibody to the respective components of the recombinant vaccine. The above results showed that rFPV-HA-NA could be a potential vaccine to replace current inactivated vaccines for preventing AI.

      http://www.hvri.ac.cn/new/news_.asp?...culture&id=738


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