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China - FAO H7N9 situation update: 1364 confirmed cumulative human cases, including 498 deaths - March 29, 2017

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  • China - FAO H7N9 situation update: 1364 confirmed cumulative human cases, including 498 deaths - March 29, 2017

    I have updated our case list with this FAO report. I add case details when provided by the Hong Kong CHP on their weekly AI report. link



    H7N9 situation update

    29 March 2017, 17:00 hours; Rome

    The next update will be issued on 5 April 2017

    Disclaimer

    Information provided herein is current as of the date of issue. Information added or changed since the last H7N9 situation update appears in red. Human cases are depicted in the geographic location of their report. For some cases, exposure may have occurred in one geographic location but reported in another. For cases with unknown onset date, reporting date was used instead. FAO compiles information drawn from multiple national (Ministries of Agriculture or Livestock, Ministries of Health, Provincial Government websites; Centers for Disease Prevention and Control [CDC]) and international sources (World Health Organization [WHO], World Organisation for Animal Health [OIE]) as well as peer-reviewed scientific articles. FAO makes every effort to ensure, but does not guarantee, accuracy, completeness or authenticity of the information. The designation employed and the presentation of material on the map do not imply the expression of any opinion whatsoever on the part of FAO concerning the legal or constitutional status of any country, territory or sea area, or concerning the delimitation of frontiers.


    Overview

    Situation: Influenza A(H7N9) virus with pandemic potential.
    Country: China; three human cases originated in China and were reported in Malaysia (1) and Canada (2).
    Number of human cases: 1364 confirmed; 498 deaths (since February 2013).

    Number of new findings in birds or the environment since last update (22 March 2017): 29.
    Number of new human cases since last update (22 March 2017): 15.
    Provinces/municipalities: Beijing, Chongqing, Shanghai and Tianjin municipalities; Anhui, Fujian, Guangdong, Guizhou, Hebei, Henan, Hubei, Hunan, Jiangsu, Jiangxi, Jilin, Liaoning, Qinghai, Shandong, Sichuan, Taiwan, Yunnan and Zhejiang Provinces of China; Hong Kong SAR; Macao SAR, Guangxi, Ningxia Hui and Xinjiang Uyghur Autonomous Regions; Sabah (Malaysia); British Columbia (Canada).
    Animal/environmental findings: around 2,500 virological samples from the environment, chickens, pigeons, ducks and a tree sparrow tested positive; positives mainly from live bird markets, vendors and some commercial or breeding farms.

    Highly pathogenic virus findings: Out of the 1364 confirmed human cases, H7N9 virus isolates from three cases (two from Guangdong and one from Taiwan Provinces) were found to be highly pathogenic for chickens. In addition, the H7N9 highly pathogenic avian influenza virus was detected in 16 chicken and 6 environmental samples from Guangdong Province and from a large farm in Hunan Province [reference].
    Note:The United States Department of Agriculture (USDA) National Veterinary Services Laboratories (NVSL) have confirmed a H7N9 highly pathogenic (Tennessee), and a H7N9 low pathogenic avian influenza virus (Tennessee, Alabama, Kentucky). Sequencing of the genome confirmed that they are of North American wild bird lineage origin. These viruses are thus not the same as the ones currently circulating in China. [reference1, reference 2, reference 3, reference 4, reference 5]


    FAO actions: liaise with China and partners, monitor situation, monitor virus evolution, conduct market chain analysis, risk assessment, surveillance guidance and communication. Map 1. Human cases and positive findings in birds or the environment

    Click to enlarge - Note: Human cases are depicted in the geographic location where they were reported; for some cases, exposure may have occurred in a different geographic location. Precise location of 20 human cases in Anhui (2), Beijing (1), Guangdong (1), Guangxi (1), Hebei (2), Hunan (1), Hubei (2), Jiangsu (1), Jiangxi (5), Sichuan (2) and Zhejiang (2) Provinces are currently not known, these cases are therefore not shown on the map.



    Situation update

    Animals

    • 27 March, Guangxi: Qinzhou City CDC conducted H7N9 environmental sampling where 111 samples were collected from feeding water (43), chopping equipment (44) and feces (24). Three samples from Xinxu Food Market, Shaping Town Market and the Old Town Longxiang Street Market tested positive for H7N9 virus nucleic acid. These markets are closed from 28 March to 10 April. [reference]
    • 26 March, Hunan: Loudi City has closed LBMs in Youxi Township (Xinhua County) from 26 March to 30 April [reference].
    • 24 March, Guangdong: In Yangjiang, citywide suspension of all LBMs (including live poultry wholesale markets & live poultry retail markets) from 26 to 28 March, after the city CDC detected H7N9 virus nucleic acid in 3 out of 60 environmental samples from three markets in Jiangcheng District [reference].
    • 24 March, Guangxi: In Beihai City, Wenming Road Market (Haicheng District) has been suspended after the detection of two H7N9 positive environmental samples (cage sample and waste water on ground surface) [reference]. A week earlier, two samples tested positive for H7N9 in Shanghai Road Market and Donghai Market in Haicheng District. The two markets were temporarily closed, and all other live bird markets in the city are to conduct cleaning, disinfection, and strictly follow the "1110" rule [reference].
    • 19 March, Hunan: the Veterinary Department of Dong'an County, Yongzhou City, found avian influenza suspected clinical signs in a layer chicken farm. Out of a 189,676 susceptible bird population 29,760 were found sick, of which 18,497 died. The National Avian Influenza Reference Laboratory confirmed H7N9 HPAI on 24 March. A total of 171,179 birds were culled and disposed [reference].
    • 16 March, Guizhou: Qiannan Buyei and Miao Autonomous Prefecture has temporary suspended live bird markets from 16 to 30 March (15 days) in Guiding County [reference].
    Figure 1. Number of positive virological samples from birds or the environment, by province and origin as of 29 March 2017. Information provided corresponds to both high and low pathogenic H7N9 viruses.

    Click to enlarge

    Figure 2. Number of H7N9 virus isolations from poultry and environmental surveillance conducted by the Ministry of Agriculture, China, by month as of 28 March 2017. Courtesy: FAO ECTAD China

    Click to enlarge

    Map 2. Highly pathogenic H7N9 virus confirmed in birds or the environment since February 2017 and as of 28 March, Ministry of Agriculture, China. Courtesy: FAO ECTAD China

    Click to enlarge

    Humans

    • Since the last update (22 March 2017), 15 new human cases have been reported in Guangxi (4), Hunan (4), Hubei (2), Zhejiang (2), Guizhou (1), Anhui (1), Fujian (1).

    Figure 3. Number of officially reported human cases since February 2013 as of 22 March 2017 29 March 2017. Information provided corresponds to both high and low pathogenic H7N9 viruses.

    Click to enlarge

    Figure 4. Incidence of officially reported human cases by month, based on onset date as of 29 March 2017. Information provided corresponds to both high and low pathogenic H7N9 viruses.

    Click to enlarge - Note: For cases with unknown onset dates from wave 1 (n=7), wave 2 (n=2), wave 3 (n=146), wave 4 (n= 27) and wave 5 (n=449) reporting dates were used instead.

    Publications

    • In addition to the surveillance findings by MoA and MoH, 1,728 virologically positive samples have also been reported in 12 peer-reviewed articles (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12). A total of 71,920 samples have been collected in these studies since April 2013, of which 1,728 (2.4%) were positive for H7N9 (1,215 environmental samples, 501 chickens, 1 goose and 1 tree sparrow).

    FAO?s support to countries





    (I really like this report. Thanks FAO!)
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