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ECDC H7N9 [n=453 (175)] Communicable disease threats report 36, 31 August - 6 September 2014 (05 Sep 2014)

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  • ECDC H7N9 [n=453 (175)] Communicable disease threats report 36, 31 August - 6 September 2014 (05 Sep 2014)

    ECDC- Communicable disease threats report 36, 31 August - 6 September 2014 (05 Sep 2014)

    Influenza A(H7N9) - China - Monitoring human cases Opening date: 31 March 2013 Latest update: 4 September 2014 Update of the week

    In March 2013, a novel avian influenza A(H7N9) virus was detected in patients in China.

    Since then, 453 cases have been reported, including 175 deaths.

    No autochthonous cases have been reported from outside of China. Most cases have been unlinked, and sporadic zoonotic transmission from poultry to humans is the most likely explanation for the outbreak.

    Sustained person-to-person transmission has not been documented and transmission peaked during the winter of 2013-2014. The reason for this pattern is not obvious. Since October 2013, 318 cases have been reported, the majority from previously affected provinces or in patients who visited these provinces prior to onset of illness.

    Since the last monthly update on 6 August 2014, two new cases of A(H7N9) have been reported. A 66-year-old female, who has since passed away, and a 53-year-old male, both from a previously unaffected area of Xinjiang Uygur Autonomous Region.


    Epidemiological summary
    In March 2013, a novel avian influenza A(H7N9) virus was detected in patients in China. Since then, human cases have continued to be reported, and as of 4 September 2014, there were 453 laboratory-confirmed cases:

    Zhejiang (139),
    Guangdong (109),
    Jiangsu (56),
    Shanghai (42),
    Fujian (22),
    Hunan (24),
    Anhui (18),
    Jiangxi (6),
    Henan (4),
    Beijing (4),
    Guangxi (4),
    Shandong (4),
    Hebei (1),
    Guizhou (1),
    Jilin (2),
    Xinjiang Uygur (2),
    Hong Kong (10),
    Taiwan (4) and one imported case in Malaysia.

    In addition, there was one case in Malaysia and one fatal case in Canada, both exported from China.

    The second wave of the outbreak started in October 2013.

    Since then 318 cases have occurred. The number of reported cases has been declining since April 2014 and only sporadic cases have been reported during the past months.

    Most cases have developed severe respiratory disease. One hundred and seventy-five patients have died.

    http://www.ecdc.europa.eu/en/publica...5-sep-2014.pdf

    Is that a typo for Canada (H5N1?) and is there a 2nd case in Malaysia (MERS?) or is it really H7N9 ???????????

    That is a very high fatal case count of 175!

    Some further clarification from ECDC would be helpful!

    My last numbers from the Mainland China MOH is 436 at least 157 fatal cases ...pending the recent two cases and 1 death!

  • #2
    Re: ECDC H7N9 [n=453 (175)] Communicable disease threats report 36, 31 August - 6 September 2014 (05 Sep 2014)

    http://www.nhfpc.gov.cn/zhuzhan/yqxx/lists.shtml
    People's Republic of China Ministry of Health and Family Planning Commission, Epidemic Information

    http://www.nhfpc.gov.cn/yjb/s3578/20...3f72efd4.shtml
    People's Republic of China Ministry of Health and Family Planning 2013-07-10, June 2013 people infected with H7N9 bird flu Overview, [n=132 (43)]

    http://www.nhfpc.gov.cn/yjb/s3578/20...e53ac78e.shtml
    People's Republic of China Ministry of Health and Family Planning 2013-08-09, July 2013 people infected with H7N9 bird flu Overview, [n=133 (44)]

    http://www.nhfpc.gov.cn/yjb/s3578/20...07742685.shtml
    People's Republic of China Ministry of Health and Family Planning 2013-09-10, August 2013 people infected with H7N9 bird flu Overview, [n=134 (45)]

    http://www.nhfpc.gov.cn/yjb/s3578/20...5dade1b5.shtml
    People's Republic of China Ministry of Health and Family Planning 2013-10-11, September 2013 outbreak of human infection with H7N9 avian influenza overview, [n=134 (45)]

    http://www.nhfpc.gov.cn/yjb/s3578/20...d2625fd4.shtml
    People's Republic of China Ministry of Health and Family Planning 2013-11-08, October 2013 people infected with H7N9 bird flu Overview, [n=136 (45)]

    http://www.nhfpc.gov.cn/jkj/s3578/20...45069a11.shtml
    People's Republic of China Ministry of Health and Family Planning 2014-02-13, 2013 National Year of notifiable infectious diseases cases [n=19 (1) ….note was not notifiable prior to November 2013 see above for H7N9 updates for 2013)

    http://www.nhfpc.gov.cn/jkj/s3577/20...5f0f5edd.shtml
    People's Republic of China Ministry of Health and Family Planning 2013-11-04, National Health and Family Planning Commission Notice on the adjustment of the statutory management of infectious diseases AXA CDC Fa [2013] No. 28

    http://www.nhfpc.gov.cn/zhuzhan/zcjd...2930aa6f.shtml
    People's Republic of China Ministry of Health and Family Planning 2013-11-04, Interpretation on the part of the National Health and Family Planning Commission of notifiable infectious disease management work on adjustments

    http://www.nhfpc.gov.cn/jkj/s3578/20...22fdaa71.shtml
    People's Republic of China Ministry of Health and Family Planning 2013-12-16, November 2013 National Overview of legal infectious diseases [n=3 (1)]

    http://www.nhfpc.gov.cn/jkj/s3578/20...f3c3d4f0.shtml
    People's Republic of China Ministry of Health and Family Planning 2014-01-10, December 2013 National Overview of legal infectious diseases [n=5 (0)]

    http://www.nhfpc.gov.cn/jkj/s3578/20...b26f8349.shtml
    People's Republic of China Ministry of Health and Family Planning 2014-02-10, January 2014 National Overview of legal infectious diseases [n=127 (31)]

    http://www.nhfpc.gov.cn/jkj/s3578/20...9b63be30.shtml
    People's Republic of China Ministry of Health and Family Planning 2014-03-07, February 2014 National Overview of legal infectious diseases
    http://www.nhfpc.gov.cn/jkj/s3578/20...9d89de0c.shtml

    People's Republic of China Ministry of Health and Family Planning 2014-04-08, March 2014 National Overview of legal infectious diseases [n=24 (24)] ...*** 24 deaths in five cases reported incidence of this month died this month, and the remaining 19 cases reported this month reported the incidence of previous death

    http://www.nhfpc.gov.cn/jkj/s3578/20...5ae6e744.shtml
    People's Republic of China Ministry of Health and Family Planning 2014-05-08, April 2014 National Overview of legal infectious diseases,

    http://www.nhfpc.gov.cn/jkj/s3578/20...6530ba5f.shtml
    People's Republic of China Ministry of Health and Family Planning, 2014-06-10, May 2014 National Overview of legal infectious diseases

    http://www.nhfpc.gov.cn/jkj/s3578/20...64d0b1a6.shtml
    People's Republic of China Ministry of Health and Family Planning 2014-07-11, June 2014 National Overview of legal infectious diseases

    http://www.nhfpc.gov.cn/jkj/s3578/20...1f485041.shtml
    People's Republic of China Ministry of Health and Family Planning, July 2014 National Notifiable Infectious Diseases Overview , 2014-08-11 [n=1 (3)] Guangdong [n=0 (1)] pending 2 provincial fatal cases??? [Mainlad China n=436 (at least 152)]


    March 31 2013 [n=136 (45)]
    Nov [n=3 (1)]
    December (n=5 (0)]
    January [n=127 (13)]
    February [n=99 (41)]
    March [n=24 (24)]
    April [n=23 (13)]
    May [n=16 (6)]
    June [n=2 (6)]
    July [n=1 (3)]
    Aug * pending report for August .... Should come out on the 10 or 11th of September!
    ------------
    At [n=438 (at least 152)]

    Outside of China= 15 other cases = 453 (for fatal cases see flutrackers line list)

    Now I do realise WHO reported more fatal cases in 2013 and 2014 from the MOH China!

    This is only giving a tentative picture of this speculative ECDC report!

    Again don't mind my line list reference notes... they are the Provincial Notifiable Infectious Diseases reports to cross reference!
    Last edited by Biological; September 7th, 2014, 07:30 PM. Reason: removed some notes!

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    • #3
      Re: ECDC H7N9 [n=453 (175)] Communicable disease threats report 36, 31 August - 6 September 2014 (05 Sep 2014)

      WHO risk assessment of human infection with avian influenza A(H7N9) virus 27 June 2014
      Clipping:

      Human cases of avian influenza A(H7N9) virus infection to date
      A total of 450 laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus, including 165 deaths, have been reported to WHO: 435 cases by China National Health and Family Planning Commission, four cases by the Taipei Centers for Disease Control (Taipei CDC), ten cases by the Centre for Health Protection, China, Hong Kong SAR, and one case in a Chinese traveller, reported from Malaysia. Since June 2013 (second wave) until 27 June 2014, 317 cases were reported1.

      http://www.who.int/influenza/human_a...une14.pdf?ua=1

      If use June and July and pending August MOH reports with a total of [n=3 (9)]

      = 438 or 453 (174) 175 fatal cases! Now it less speculative!

      Now the two additional cases in Canada and Malaysia ... well this needs further clarification!

      Comment


      • #4
        Re: ECDC H7N9 [n=453 (175)] Communicable disease threats report 36, 31 August - 6 September 2014 (05 Sep 2014)

        Public Health Notice: H7N9 avian flu in China

        08 Sep 2014
        Information is reviewed on a regular basis and updated as required.
        Why you should take note

        Since the first notification at the end of March 2013, China has been reporting to the World Health Organization (WHO) confirmed cases of a type of avian influenza virus in humans identified as A(H7N9). Most cases develop severe pneumonia and breathing difficulties with some resulting in death. Official numbers are available here.
        Risk to Canadians

        The avian influenza (H7N9) virus causing illness in people in China has not been identified in people or birds in Canada.


        While emerging information suggests the possibility of some limited human-to-human transmission of this virus in China, there has been no evidence of ongoing human-to-human transmission. The risk to Canadians remains low.



        Outside mainland China, travel-related cases have been confirmed in Taiwan, Hong Kong and Malaysia, following poultry exposure traced to a number of eastern provinces in China. However, there is no indication that international spread has occurred, as contacts of the travelers did not develop illness.
        There is no risk of catching the flu virus by eating well-cooked poultry. Canada does not import raw poultry or raw poultry products from China.
        Canadians can help protect themselves and their fellow citizens from influenza in general by:
        • Washing hands frequently;
        • Covering coughs and sneezes;
        • Keeping common surfaces clean; and
        • Staying home when sick.
        Travel information

        While the Agency is not advising any travel restrictions related to this event at this time, a Travel Health Notice has been posted to provide advice to Canadian travellers. We will continue to monitor this situation very closely and advise Canadians as appropriate.
        What the Public Health Agency of Canada is doing

        The Public Health Agency is working closely with its national and international partners, including the World Health Organization (<abbr>WHO</abbr>), to monitor flu activity in Canada and around the world.
        The full extent of this outbreak, the source of infection and mode of transmission are currently unknown. Chinese health authorities and experts from the WHO continue to investigate the outbreak.
        Activities that the Agency is engaged in include the following:
        • on an ongoing basis, the Agency and international partners assess the risk of H7N9 being transmitted to Canadian travellers. The Agency also works with the Canada Border Services Agency, international partners, and health and point of entry authorities to support the screening and detection of ill international travellers.
        • liaising with the Chinese infectious disease prevention authorities on this outbreak through an Agency medical expert based in Beijing.
        • posting information to support professionals working in the field or otherwise affected by this issue:
        The Agency’s National Microbiology Laboratory (NML) has diagnostic tests available that can rapidly detect the H7N9 virus as well as antibodies against the virus. Having the ability to detect H7N9 antibodies in people is important as it signals previous exposure to the virus.
        Additionally, the Agency’s NML is:
        • providing technical expertise and working closely with provincial public health laboratories to ensure they also have the tools and tests required to detect the H7N9 virus.
        • collaborating closely and regularly with counterparts in the United States and Europe, sharing important scientific information on this new flu strain.
        • conducting advanced research on a live sample of the H7N9 virus, including:
          • determining if antiviral drugs are effective against the virus and
          • developing and testing vaccines to determine if they protect against the virus.
        All research work with the live H7N9 virus is being done under strictly controlled settings in high-containment laboratories.
        Additional information

        Media Contact

        Public Health Agency of Canada
        Media Relations
        (613) 957-2983

        http://www.phac-aspc.gc.ca/phn-asp/2...9-0403-eng.php
        Last edited by sharon sanders; September 7th, 2014, 08:46 PM. Reason: formatted the entire report for posterity

        Comment


        • #5
          Re: ECDC H7N9 [n=453 (175)] Communicable disease threats report 36, 31 August - 6 September 2014 (05 Sep 2014)

          Communicable disease threats report, 7-13 September 2014, week 37
          12 Sep 2014

          ERRATUM: Following the week 36 CDTR, ECDC would like to clarify that no imported cases of A(H7N9) have been reported from outside of China to date, except for the single case imported to Malaysia.

          The CDTRs for weeks 23-36 incorrectly included a mention of an imported case in Canada.

          see report:

          http://www.ecdc.europa.eu/en/publica...3dbb90&ID=1168

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