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Ghana - 1 new outbreak of highly pathogenic avian influenza virus H9N2 in birds on farm, Brong-Ahafo (OIE, February 14, 2018)
Translation Google
shock! H9N2 has become a highly pathogenic bird flu?
New animal husbandry network 2018-02-27 09:12:14
...
In mid-February, the Ghanaian Ministry of Agriculture informed that one outbreak of HPAI H9N2 subtype occurred in the country, 4,225 laying hens were infected and 12,997 were destroyed.
H9N2 avian influenza virus is generally believed to belong to the group of low pathogenic avian influenza virus. The morbidity and mortality of chickens infected by chickens are very low. The main hazards are immunosuppression and secondary infection of other pathogens. The "highly pathogenic" outbreak worthy of raising chicken people attach great importance.
Status: Widely popular, enhanced virulence
The Bird Flu Research Laboratory of Harbin Veterinary Research Institute found that the H7 subtype positive flock in the bird flu positive chickens accounted for 37.12% of the total, followed by the H5 subtype of 28.62% , Confirming that the H9N2 avian influenza is widespread in our country and is the main subtype of the current avian influenza.
H9 subtype of avian influenza virus strains are divided into A, B, C three antigen groups, H9N2 virus gradually evolved. Bi Yingzuo, a professor at South China Agricultural University, said that the strain of the most popular strain in China in recent 20 years was mainly 9.4.2, with the main epidemic sub-branch starting in late 2013 in China.
After years of tracking H9 subtype avian influenza virus strains, Liang Aqiao, technical director of Guangdong Wintech's Dahua Agricultural Biological Technology Co., Ltd., found that the A antigenic strain population gradually disappeared. The B antigenic strain group was transitional in nature and decreased after reaching its peak in 2014. C antigen Strains become the current dominant epidemic strains, with h9.4.2.5 branch-based.
Chinese Academy of Engineering Liu Xiu-fan that H9 subtype of bird flu is the most widely poultry in our country, the most rapid spread of the bird flu and synergistic effect with other pathogens, the evolutionary process was very stable internal strains of the genotype G57 genotype, Toxicity to poultry, mammals have an increasing trend of infection, endangering huge.
Hazard: continuous variation, synergistic disease
Like most influenza viruses, H9N2 is constantly mutating and new and emerging strains emerge.
In 2017, for the first time, the CDC in Jiangxi Province separated the H9N6 virus from chickens for the first time in mainland China. Liao Ming, a professor at South China Agricultural University, pointed out that although the recombinant virus currently has no clinical manifestations and has not caused any human cases of infection, the disease has sounded the alarm: two bird flu serotypes (H6 and H9) on the market, Unforeseen changes may occur in the future.
In addition, the most lethal strain of chicken H7N9 virus is also closely related to H9N2.
Liao Ming pointed out that H7N9 is still in an unstable state, easy to get some gene fragments from the H9 virus gene pool for recombination, making it suitable for survival in different environments. Only control of H9 virus contamination can halt the further development of H7 bird flu.
In addition to continuous variation, H9 has a synergistic effect with multiple pathogens, which also poses a greater challenge for the prevention and control of the disease.
Cong Qiu Shi, chief technical officer of KA Division, Harbin Institute of Technology Co., Ltd., a biological vaccine company, told Xinmu News Network about the new bird situation that the infection process of avian influenza is due to the HA being proteolytically cleaved by HA into HA1 and HA2. Staphylococcus aureus secretion of protease, either in vivo or in vitro, have the function of cracking HA, can greatly enhance the ability of bird flu infection.
In addition, it is actually found that the co-infection of H9 bird flu with Escherichia coli causes a very high mortality rate. Other factors, such as Mycoplasma gallisepticum destroying the integrity of the respiratory tract, can lead to increased flu infections. Mycotoxins, especially aflatoxin, can cause immunosuppression and can exacerbate symptoms and even cause death in chickens.
...
Ghana - 1 new outbreak of highly pathogenic avian influenza virus H9N2 in birds on farm, Brong-Ahafo (OIE, February 14, 2018)
Translation Google
shock! H9N2 has become a highly pathogenic bird flu?
New animal husbandry network 2018-02-27 09:12:14
...
In mid-February, the Ghanaian Ministry of Agriculture informed that one outbreak of HPAI H9N2 subtype occurred in the country, 4,225 laying hens were infected and 12,997 were destroyed.
H9N2 avian influenza virus is generally believed to belong to the group of low pathogenic avian influenza virus. The morbidity and mortality of chickens infected by chickens are very low. The main hazards are immunosuppression and secondary infection of other pathogens. The "highly pathogenic" outbreak worthy of raising chicken people attach great importance.
Status: Widely popular, enhanced virulence
The Bird Flu Research Laboratory of Harbin Veterinary Research Institute found that the H7 subtype positive flock in the bird flu positive chickens accounted for 37.12% of the total, followed by the H5 subtype of 28.62% , Confirming that the H9N2 avian influenza is widespread in our country and is the main subtype of the current avian influenza.
H9 subtype of avian influenza virus strains are divided into A, B, C three antigen groups, H9N2 virus gradually evolved. Bi Yingzuo, a professor at South China Agricultural University, said that the strain of the most popular strain in China in recent 20 years was mainly 9.4.2, with the main epidemic sub-branch starting in late 2013 in China.
After years of tracking H9 subtype avian influenza virus strains, Liang Aqiao, technical director of Guangdong Wintech's Dahua Agricultural Biological Technology Co., Ltd., found that the A antigenic strain population gradually disappeared. The B antigenic strain group was transitional in nature and decreased after reaching its peak in 2014. C antigen Strains become the current dominant epidemic strains, with h9.4.2.5 branch-based.
Chinese Academy of Engineering Liu Xiu-fan that H9 subtype of bird flu is the most widely poultry in our country, the most rapid spread of the bird flu and synergistic effect with other pathogens, the evolutionary process was very stable internal strains of the genotype G57 genotype, Toxicity to poultry, mammals have an increasing trend of infection, endangering huge.
Hazard: continuous variation, synergistic disease
Like most influenza viruses, H9N2 is constantly mutating and new and emerging strains emerge.
In 2017, for the first time, the CDC in Jiangxi Province separated the H9N6 virus from chickens for the first time in mainland China. Liao Ming, a professor at South China Agricultural University, pointed out that although the recombinant virus currently has no clinical manifestations and has not caused any human cases of infection, the disease has sounded the alarm: two bird flu serotypes (H6 and H9) on the market, Unforeseen changes may occur in the future.
In addition, the most lethal strain of chicken H7N9 virus is also closely related to H9N2.
Liao Ming pointed out that H7N9 is still in an unstable state, easy to get some gene fragments from the H9 virus gene pool for recombination, making it suitable for survival in different environments. Only control of H9 virus contamination can halt the further development of H7 bird flu.
In addition to continuous variation, H9 has a synergistic effect with multiple pathogens, which also poses a greater challenge for the prevention and control of the disease.
Cong Qiu Shi, chief technical officer of KA Division, Harbin Institute of Technology Co., Ltd., a biological vaccine company, told Xinmu News Network about the new bird situation that the infection process of avian influenza is due to the HA being proteolytically cleaved by HA into HA1 and HA2. Staphylococcus aureus secretion of protease, either in vivo or in vitro, have the function of cracking HA, can greatly enhance the ability of bird flu infection.
In addition, it is actually found that the co-infection of H9 bird flu with Escherichia coli causes a very high mortality rate. Other factors, such as Mycoplasma gallisepticum destroying the integrity of the respiratory tract, can lead to increased flu infections. Mycotoxins, especially aflatoxin, can cause immunosuppression and can exacerbate symptoms and even cause death in chickens.
...
