Pakistan - 2 new outbreaks of highly pathogenic avian influenza H5N8 in birds, Islamabad Capital Territory (OIE, February 26, 2019)

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Highly pathogenic influenza A viruses (infection with) (non-poultry including wild birds), Pakistan

Information received on 26/02/2019 from Dr Khurshid Ahmad, Animal Husbandry Commissioner, Government of Pakistan, Ministry of National Food Security and Research, Islamabad, Pakistan

Summary Report type Immediate notification Date of start of the event 02/01/2019 Date of confirmation of the event 15/02/2019 Report date 26/02/2019 Date submitted to OIE 26/02/2019 Reason for notification Recurrence of a listed disease Date of previous occurrence 02/02/2018 Manifestation of disease Clinical disease Causal agent Highly pathogenic influenza A virus Serotype H5N8 Nature of diagnosis Clinical, Laboratory (advanced) This event pertains to a defined zone within the country

New outbreaks (2)

Outbreak 1 F 11/3, Islamabad Capital Territory Date of start of the outbreak 02/01/2019 Outbreak status Resolved (22/02/2019) Epidemiological unit Other Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Mallard:Anas platyrhynchos(Anatidae) 10 7 7 3 0 Common Guineafowl:Numida meleagris(Numididae) 8 6 6 2 0 Coscoroba Swan:Coscoroba coscoroba(Anatidae) 50 50 50 0 0 Affected population Adult Guinea fowl, swan and duck were submitted for laboratory analysis.

Outbreak 2 Diplomatic Enclave, Islamabad Capital Territory Date of start of the outbreak 07/02/2019 Outbreak status Resolved (15/02/2019) Epidemiological unit Other Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered House Crow:Corvus splendens(Corvidae) 1 1 0 0 Affected population An adult dead crow was submitted for analysis to the National Reference Laboratory for Poultry Diseases.

Summary of outbreaks Total outbreaks: 2 Total animals affected Species Susceptible Cases Deaths Killed and disposed of Slaughtered Mallard:Anas platyrhynchos(Anatidae) 10 7 7 3 0 Common Guineafowl:Numida meleagris(Numididae) 8 6 6 2 0 Coscoroba Swan:Coscoroba coscoroba(Anatidae) 50 50 50 0 0 House Crow:Corvus splendens(Corvidae) 1 1 0 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Mallard:Anas platyrhynchos(Anatidae) 70.00% 70.00% 100.00% 100.00% Common Guineafowl:Numida meleagris(Numididae) 75.00% 75.00% 100.00% 100.00% Coscoroba Swan:Coscoroba coscoroba(Anatidae) 100.00% 100.00% 100.00% 100.00% House Crow:Corvus splendens(Corvidae) ** ** 100.00% ** *Removed from the susceptible population through death, destruction and/or slaughter **Not calculated because of missing information

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments Clinical symptoms swan, duck and Guinea fowl included diarrhea, respiratory signs and sudden death. The dead swan, duck and Guinea fowl were submitted to the National Reference Laboratory for Poultry Diseases (NRLPD) and tested positive for influenza A H5N8 virus. A dead crow was sent by an official from the British High Commission to the NRLPD for analysis and tested positive for influenza A H5N8 virus.

Control measures Measures applied Movement control inside the country Screening Official destruction of animal products Official disposal of carcasses, by-products and waste Control of wildlife reservoirs Selective killing and disposal Disinfection Vaccination permitted (if a vaccine exists) No treatment of affected animals Measures to be applied No other measures

Diagnostic test results Laboratory name and type Species Test Test date Result National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Common Guineafowl virus neutralisation test (VNT) 22/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Coscoroba Swan enzyme-linked immunosorbent assay (ELISA) 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Common Guineafowl enzyme immunoassay (EIA) membrane test 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Common Guineafowl real-time PCR 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Common Guineafowl virus isolation 22/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Coscoroba Swan real-time PCR 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Coscoroba Swan virus isolation 22/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Coscoroba Swan virus neutralisation test (VNT) 22/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) House Crow enzyme-linked immunosorbent assay (ELISA) 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) House Crow real-time PCR 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) House Crow virus isolation 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) House Crow virus neutralisation test (VNT) 26/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Mallard enzyme-linked immunosorbent assay (ELISA) 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Mallard real-time PCR 15/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Mallard virus isolation 22/02/2019 Positive National Reference Laboratory for Poultry Diseases (NRLPD) (Regional Reference Laboratory) Mallard virus neutralisation test (VNT) 22/02/2019 Positive

Future Reporting The event is continuing. Weekly follow-up reports will be submitted.

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http://www.oie.int/wahis_2/public/wa...reportid=29686