South Korea: "Disease Management Headquarters, Tamiflu period 6 weeks → extended to 12 weeks" for the prevention and treatment of influenza pandemic (AI) infections

[Treyfish]

"The government has not proved the safety of AI drugs,
Shipping Time | 2017/01/02 18:39



Satongon "Disease Management Headquarters, Tamiflu period 6 weeks → extended to 12 weeks"

SEOUL, Jan. 2 (Yonhap) - The government has increased the duration of medication for the prevention and treatment of influenza pandemic (AI) infections,

According to the Democratic Party's lawmaker, the Department of Disease Control and Prevention has changed the guidelines for the administration of anti-viral drugs (Tamiflu) for the prevention of AI human infection.

The main point of the change is to allow the Tamiflu dosage instructions to be taken for up to 12 weeks from the consecutive 6-week withdrawal.

But the safety and efficacy of Tamiflu is only proven for up to six weeks, the source said. This is because the clinical trials were held for up to six weeks.

A related official of the Disease Control Division said, "Due to the complaints of the animal husbandry department and the health center that the inspections of the animal husbandry department and the public health center do not work for 6 weeks due to insufficient on-site manpower, .

"It is dangerous gambling as a guarantee of the people's right to life," he said. "The government has decided to prevent the use of preventive medicine in excess of 6 weeks due to manpower replacement, More monitoring of the workforce should be done. "http://www.yonhapnews.co.kr/bulletin...ML?from=search

[sharon sanders]

I don't see the increase of treatment time on the CDC site but it looks like the above article is a direct quote from an official.

[Treyfish]

"Tamiflu, 12-week medication safety for preventive purposes" ... Explanation of risk
| 2017/01/04 10:13


Disease Management Headquarters "No one has taken more than 6 weeks of high-risk"

(Seoul-Yonhap News) Shin Jae-woo, a researcher at the Ministry of Health and Welfare, said the use of Tamiflu, an antiviral drug, to prevent bird flu, Emphasized safety and set out to evolve.

Health officials said that none of the high-risk groups exposed to AI, such as poultry disposal workers, had taken tamiflu for more than six weeks, and there were no suspected cases.

The Korea Center for Disease Control and Prevention announced on April 4, "The Korea Food and Drug Administration (KFDA) has clarified that the safety of Tamiflu has been secured for up to 12 weeks for the prevention of influenza in immunocompromised patients." .

In addition, three studies conducted abroad from 2011 to 2012 stressed the safety of Tamiflu prophylaxis.

The study, published in the Journal of Antimicrobial Chemotherapy in 2012, said that it was safe to administer healthy Tamiflu for 16 weeks.

According to the Center for Disease Control and Prevention, "Tamiflu is basically a treatment for influenza, but it has a preventive effect. In view of the fact that the safety of the drug has been established, allow for continuous use for up to 6 weeks for prevention purposes. "I explained that the cumulative period should not exceed 12 weeks."

According to the Food and Drug Administration, Tamiflu has a preventive effect for up to 6 weeks when given once a day at 75 mg. For this reason, the period of administration of Tamiflu has been fixed at 6 weeks. However, the government changed the total medication period from 6 weeks to 12 weeks when AI spreads and manpower disposal is short.

The disease management headquarters said, "The possibility of tolerance for long-term antiviral medication is" resistance occurs when a virus and a drug are encountered. Abuse of antiviral drugs in influenza infected patients may result in tolerance, I do not increase it. "

In addition, the genetic analysis of the current H5N6 strain of AI virus in Korea shows no resistance to Tamiflu.

The government said it had managed to manage 17,463 people from Nov. 17 last year, when it first began disposing of livestock, to high-risk AI exposures, and no one has taken Tamiflu in more than six weeks.

High-risk groups are monitored during the latency period (10 days) after AI exposure, and to date, 12,229 have been identified as not infected and have been excluded from high-risk groups. http://www.yonhapnews.co.kr/bulletin...057600017.HTML