The first fatal human infection with highly pathogenic avian influenza A (H5N1) virus detected in Bangladesh
Published: September 2013
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Published By: icddr,b
Health and Science Bulletin, VOLUME 11 ? NUMBER 3 ? SEPTEMBER 2013 ISSN 1729-343X
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Previously six human cases of avian influenza A (H5N1) were identified in Bangladesh between 2008 and 2012; all cases experienced mild respiratory illness.
On 12 February 2013, a 23-month old boy from Comilla was hospitalized for febrile convulsions and enrolled in a respiratory virus research study. Laboratory tests conducted on 12 March suggested that the boy had influenza A (H5) infection. This was the 7th case of A (H5N1) identified in Bangladesh. A joint IEDCR-icddr,b outbreak response team investigated to explore the child?s exposure history and clinical outcome and to look for additional cases in the community. Several chickens raised in the family?s backyard became sick a few days before he became ill; they were slaughtered and the boy played with the carcasses. The child died on February 18 with evidence of severe pneumonia, meningitis and disseminated intravascular coagulation; no other human cases were identified. Viral sequences from the child and slaughtered chicken confirmed that both were infected with influenza A (H5N1), clade 2.3.2.1. This first identified death from avian influenza infection in Bangladesh presented primarily with neurologic rather than respiratory symptoms and was apparently infected through contact with sick chickens. Clinicians should consider avian influenza infection in the differential diagnosis for any patient with severe respiratory or neurologic infection with a history of contact with sick poultry. All such patients should be treated with oseltamivir.
see full report:
The first fatal human infection with highly | Vol. 11 No. 3 (English) (2013) | Health and Science Bulletin (Bangla and English) | icddr,b Periodicals - icddr,b
Published: September 2013
Size: 202.61 kB
Published By: icddr,b
Health and Science Bulletin, VOLUME 11 ? NUMBER 3 ? SEPTEMBER 2013 ISSN 1729-343X
Clip:
Previously six human cases of avian influenza A (H5N1) were identified in Bangladesh between 2008 and 2012; all cases experienced mild respiratory illness.
On 12 February 2013, a 23-month old boy from Comilla was hospitalized for febrile convulsions and enrolled in a respiratory virus research study. Laboratory tests conducted on 12 March suggested that the boy had influenza A (H5) infection. This was the 7th case of A (H5N1) identified in Bangladesh. A joint IEDCR-icddr,b outbreak response team investigated to explore the child?s exposure history and clinical outcome and to look for additional cases in the community. Several chickens raised in the family?s backyard became sick a few days before he became ill; they were slaughtered and the boy played with the carcasses. The child died on February 18 with evidence of severe pneumonia, meningitis and disseminated intravascular coagulation; no other human cases were identified. Viral sequences from the child and slaughtered chicken confirmed that both were infected with influenza A (H5N1), clade 2.3.2.1. This first identified death from avian influenza infection in Bangladesh presented primarily with neurologic rather than respiratory symptoms and was apparently infected through contact with sick chickens. Clinicians should consider avian influenza infection in the differential diagnosis for any patient with severe respiratory or neurologic infection with a history of contact with sick poultry. All such patients should be treated with oseltamivir.
see full report:
The first fatal human infection with highly | Vol. 11 No. 3 (English) (2013) | Health and Science Bulletin (Bangla and English) | icddr,b Periodicals - icddr,b
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