Nasreen S, Uddin Khan S, Azziz-Baumgartner E, Hancock K, Veguilla V, et al. (2013) Seroprevalence of Antibodies against Highly Pathogenic Avian Influenza A (H5N1) Virus among Poultry Workers in Bangladesh, 2009. PLoS ONE 8(9): e73200. doi:10.1371/journal.pone.0073200
Highlights:
None Seropositive for Clade 2.2.2 (A/Bangladesh/207095/2008)
Farm worker (0/212) Market worker (0/210)
Eight market workers did have low HPAI H5N1 virus antibody titers by microneutralization assay; for seven workers, titers were only 2-fold above the limit of detection for this assay and were not confirmed by any other method. Slaughtering, defeathering and evisceration of poultry were associated with an HPAI H5N1 virus antibody titer of ≥20 among market workers
yes reported however did not meet seropositive criteria ; The relative risk was higher among workers who reported that they:
slaughtered (RR 11.0 [7/82 (9%) vs. 1/128 (1%), 95% CI 1.4? 87.1]), defeathered (RR 7.2 [6/62 (10%) vs. 2/148 (1%), 95% CI 1.5?34.5]) or eviscerated (RR 6.8 [6/64 (9%) vs. 2/146 (1%), 95% CI 1.4?33.0]) poultry compared to workers who did not
Weekly Schedule for the Week of 15 September 2013 - icddr,b
Clip:
Seroprevalence of antibodies against highly pathogenic Avian influenza A (H5N1) virus among poultry workers in Bangladesh, 2009
Nasreen S, Khan SU, Azziz-Baumgartner E, Hancock K, Veguilla V, Wang D, Rahman M, Alamgir ASM, Sturm-Ramirez K, Gurley ES, Luby SP, Katz JM, Uyeki TM
Clip:
We conducted a cross-sectional study in 2009 to determine the seroprevalence and risk factors for highly pathogenic avian influenza A (H5N1) [HPAI H5N1] virus antibodies among poultry workers at farms and live bird markets with confirmed/suspected poultry outbreaks during 2009 in Bangladesh. We tested sera by microneutralization assay using A/Bangladesh/207095/2008 (H5N1; clade 2.2.2) virus with confirmation by horse red blood cell hemagglutination inhibition and H5-specific Western blot assays. We enrolled 212 workers from 87 farms and 210 workers from three live bird markets. One hundred and two farm workers (48%) culled poultry. One hundred and ninety-three farm workers (91%) and 178 market workers (85%) reported direct contact with poultry that died during a laboratory confirmed HPAI H5N1 poultry farm outbreak or market poultry die-offs from suspected HPAI H5N1. Despite exposure to sick poultry, no farm or market poultry workers were seropositive for HPAI H5N1 virus antibodies (95% confidence interval 0?1%).
Highlights:
None Seropositive for Clade 2.2.2 (A/Bangladesh/207095/2008)
Farm worker (0/212) Market worker (0/210)
Eight market workers did have low HPAI H5N1 virus antibody titers by microneutralization assay; for seven workers, titers were only 2-fold above the limit of detection for this assay and were not confirmed by any other method. Slaughtering, defeathering and evisceration of poultry were associated with an HPAI H5N1 virus antibody titer of ≥20 among market workers
yes reported however did not meet seropositive criteria ; The relative risk was higher among workers who reported that they:
slaughtered (RR 11.0 [7/82 (9%) vs. 1/128 (1%), 95% CI 1.4? 87.1]), defeathered (RR 7.2 [6/62 (10%) vs. 2/148 (1%), 95% CI 1.5?34.5]) or eviscerated (RR 6.8 [6/64 (9%) vs. 2/146 (1%), 95% CI 1.4?33.0]) poultry compared to workers who did not
Weekly Schedule for the Week of 15 September 2013 - icddr,b
Clip:
Seroprevalence of antibodies against highly pathogenic Avian influenza A (H5N1) virus among poultry workers in Bangladesh, 2009
Nasreen S, Khan SU, Azziz-Baumgartner E, Hancock K, Veguilla V, Wang D, Rahman M, Alamgir ASM, Sturm-Ramirez K, Gurley ES, Luby SP, Katz JM, Uyeki TM
Clip:
We conducted a cross-sectional study in 2009 to determine the seroprevalence and risk factors for highly pathogenic avian influenza A (H5N1) [HPAI H5N1] virus antibodies among poultry workers at farms and live bird markets with confirmed/suspected poultry outbreaks during 2009 in Bangladesh. We tested sera by microneutralization assay using A/Bangladesh/207095/2008 (H5N1; clade 2.2.2) virus with confirmation by horse red blood cell hemagglutination inhibition and H5-specific Western blot assays. We enrolled 212 workers from 87 farms and 210 workers from three live bird markets. One hundred and two farm workers (48%) culled poultry. One hundred and ninety-three farm workers (91%) and 178 market workers (85%) reported direct contact with poultry that died during a laboratory confirmed HPAI H5N1 poultry farm outbreak or market poultry die-offs from suspected HPAI H5N1. Despite exposure to sick poultry, no farm or market poultry workers were seropositive for HPAI H5N1 virus antibodies (95% confidence interval 0?1%).
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