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Posted on Monday, April 25, 2022
About acute hepatitis of unknown cause in children
As of April 21, World Health Organization (WHO) reports continue to report acute hepatitis of unknown etiology in at least 169 children (1 death) in 12 countries. Of these, adenovirus was detected in 74 cases, but it is said that the causative virus is unknown. It is also unclear whether acute hepatitis is actually increasing in children. WHO has established a provisional case definition for the purpose of identifying the cause of this acute hepatitis, and is requesting each country to report cases that fall under the case definition.
On April 20, 1945, the Ministry of Health, Labor and Welfare has issued an administrative contact to local governments, etc. regarding such cases, calling attention and requesting information provision.
We have recently received a notification that one inpatient case corresponding to 2 "possible cases" of the provisional case definition (*) created by WHO has occurred, so we will announce it as attached. In the future, we will regularly compile and publish the status of case reports.
The Ministry of Health, Labor and Welfare will continue to cooperate with the governments of each country, WHO, experts, etc., and strive to collect information while paying close attention to the infection situation in other countries.
Please be considerate of the protection of personal information so that the person or family member is not identified by the media.
* WHO has established the following provisional working case definition on April 23.
1 Confirmed: None at this time. 2 Probable: Aspartate transaminase (AST) or alanine transaminase (ALT) presents with acute hepatitis (excluding hepatitis A to E *
) exceeding 500 IU / L after January 1, 2021. Children under 16 years
3 Epi-linked cases: Acute hepatitis (excluding hepatitis A to E) of any age who is a close contact of confirmed cases (before April 22) after January 1, 2021 * )
* If the result of hepatitis virus AE meets the above definition, it can be reported as "waiting for classification".
About acute hepatitis of unknown cause in children
As of April 21, World Health Organization (WHO) reports continue to report acute hepatitis of unknown etiology in at least 169 children (1 death) in 12 countries. Of these, adenovirus was detected in 74 cases, but it is said that the causative virus is unknown. It is also unclear whether acute hepatitis is actually increasing in children. WHO has established a provisional case definition for the purpose of identifying the cause of this acute hepatitis, and is requesting each country to report cases that fall under the case definition.
On April 20, 1945, the Ministry of Health, Labor and Welfare has issued an administrative contact to local governments, etc. regarding such cases, calling attention and requesting information provision.
We have recently received a notification that one inpatient case corresponding to 2 "possible cases" of the provisional case definition (*) created by WHO has occurred, so we will announce it as attached. In the future, we will regularly compile and publish the status of case reports.
The Ministry of Health, Labor and Welfare will continue to cooperate with the governments of each country, WHO, experts, etc., and strive to collect information while paying close attention to the infection situation in other countries.
Please be considerate of the protection of personal information so that the person or family member is not identified by the media.
* WHO has established the following provisional working case definition on April 23.
1 Confirmed: None at this time. 2 Probable: Aspartate transaminase (AST) or alanine transaminase (ALT) presents with acute hepatitis (excluding hepatitis A to E *
) exceeding 500 IU / L after January 1, 2021. Children under 16 years
3 Epi-linked cases: Acute hepatitis (excluding hepatitis A to E) of any age who is a close contact of confirmed cases (before April 22) after January 1, 2021 * )
* If the result of hepatitis virus AE meets the above definition, it can be reported as "waiting for classification".
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