JAMA. 2015;314(12):1218. doi:10.1001/jama.2015.11206.


Resistance to macrolides?the preferred treatment for Mycoplasma pneumoniae infections in children?may be more widespread in the United States than previous research had indicated.

In a recent study using molecular and phenotypic techniques at 6 US medical centers, investigators detected macrolide resistance in 13.2% of 91 M pneumoniae?positive specimens, most of which were obtained from patients 18 years or younger. Among the 80 respiratory specimens that included co-infection data, 32.5% had a viral pathogen in addition to M pneumoniae (Zheng X et al. Emerg Infect Dis. 2015;21[8]:1470-1472).