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Antimicrob Agents Chemother. Spread of NDM-1-producing Enterobacteriaceae in a neonatal intensive care unit, Istanbul, Turkey

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  • Antimicrob Agents Chemother. Spread of NDM-1-producing Enterobacteriaceae in a neonatal intensive care unit, Istanbul, Turkey

    [Source: Antimicrobial Agents and Chemotherapy, full page: (LINK). Abstract, edited.]


    Spread of NDM-1-producing Enterobacteriaceae in a neonatal intensive care unit, Istanbul, Turkey

    Laurent Poirel 1,2, Mesut Yilmaz 3, Ayse Istanbullu 4, Ferhat Arslan 3, Ali Mert 3, Sandrine Bernabeu 2 and Patrice Nordmann 1,2*

    Author Affiliations: <SUP>1</SUP>Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland <SUP>2</SUP>INSERM U914, South-Paris Medical School, K.-Bic?tre, France <SUP>3</SUP>Infectious Diseases and Clinical Microbiology Department <SUP>4</SUP>Medical Microbiology Department, School of Medicine, Istanbul Medipol University, Istanbul, Turkey


    ABSTRACT

    Twenty-two consecutive carbapenem-resistant enterobacterial isolates were recovered from patients hospitalized between January and April 2013 in different units at a University hospital in Istanbul, Turkey. There were Klebsiella pneumoniae producing the carbapenemases OXA-48, NDM-1, and KPC-2, Enterobacter cloacae producing NDM-1, and Escherichia coli producing OXA-48, respectively. Most of the OXA-48-producing K. pneumoniae, and all the NDM-1-producing E. cloacae, respectively, were clonally-related. The NDM-1-producing E. cloacae isolates recovered from a single neonatal intensive care unit corresponded to a single cluster highlighting the spread of that clone on that setting.


    FOOTNOTES

    *Corresponding author. Mailing address: Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, rue Albert-Gockel 3, CH-1700 Fribourg, Switzerland. Phone: 41-26-300-9581. E-mail: patrice.nordmann@unifr.ch

    Copyright ? 2014, American Society for Microbiology. All Rights Reserved.


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