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Antimicrob Agents Chemother. Carbapenemase-producing Enterobacteriaceae in Spain (2012)

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  • Antimicrob Agents Chemother. Carbapenemase-producing Enterobacteriaceae in Spain (2012)

    [Source: Antimicrobial Agents and Chemotherapy, full page: (LINK). Abstract, edited.]

    Carbapenemase-producing Enterobacteriaceae in Spain (2012)

    Jesús Oteo 1*, David Saez 1, Verónica Bautista 1, Sara Fernández-Romero 1, Juan Manuel Hernández-Molina 2, María Pérez-Vázquez 1, Belén Aracil 1, José Campos 1,3, the Spanish collaborating Group for the Antibiotic Resistance Surveillance Program

    Author Affiliations: <SUP>1</SUP>Antibiotic laboratory, Bacteriology Department, Centro Nacional de Microbiología, Majadahonda, Madrid, Spain. <SUP>2</SUP>Microbiology Department, Hospital Universitario Carlos Haya, Málaga, Spain. <SUP>3</SUP>Consejo Superior de Investigaciones Científicas, Madrid, Spain.


    We report the epidemiological impact of carbapenemases-producing Enterobacteriaceae (CPE) in Spain in 2012. Of the 237 carbapenemases detected 163 were OXA-48 group, 60 VIM-1, 8 KPC-2, 5 IMP group, and one NDM-1. Inter-hospital spread of carbapenemase-producing K. pneumoniae was due to a limited number of MLST and carbapenemases types including ST15/VIM-1, ST11/OXA-48, ST405/OXA-48, ST101/KPC-2 and ST11/VIM-1. The number of CPE in Spain has increased sharply in recent years mainly due to the emergence of OXA-48.


    * Corresponding author. Centro Nacional de Microbiología, Instituto de Salud Carlos III, Carretera Pozuelo a Majadahonda, 28220 Majadahonda, Madrid, Spain. Tel: +34—918223650; Fax: +34-915097966; E-mail:

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