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Euro Surveill. Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010

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  • Euro Surveill. Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010

    Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010 (Euro Surveill., abstract, edited)


    [Source: Eurosurveillance, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19833">Eurosurveillance - View Article</cite>. Abstract, edited.]

    Eurosurveillance, Volume 16, Issue 14, 07 April 2011

    Rapid communications

    Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010

    C A Ison 1, J Hussey 2, K N Sankar 3, J Evans 4, S Alexander 1

    1. Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, London, United Kingdom
    2. Carlton Street Clinic, Blyth, Northumberland, United Kingdom
    3. New Croft Centre, Newcastle upon Tyne, United Kingdom
    4. Health Protection Agency North East, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom

    Citation style for this article: Ison CA, Hussey J, Sankar KN, Evans J, Alexander S. Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010. Euro Surveill. 2011;16(14):pii=19833. Available online: http://www.eurosurveillance.org/View...rticleId=19833

    Date of submission: 14 March 2011


    Successful treatment of gonorrhoea is the mainstay of public health control. Cefixime and ceftriaxone, highly active third generation cephalosporins, are today the recommended first-line agents in most countries and azithromycin is a second-line agent. However, there is increasing evidence of decreasing susceptibility and emergence of therapeutic failures. In this report two cases of clinical failure to cefixime are described, one of which additionally shows failure to azithromycin and selection of a less susceptible strain during treatment.

    -
    -----<cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19833"></cite>
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