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Emerg Infect Dis. Human Infections with Non-O157 Shiga Toxin?producing Escherichia coli, Switzerland, 2000?2009
Human Infections with Non-O157 STEC, Switzerland (Emerg Infect Dis., abstract, edited)
[Source: US Centers for Disease Control and Prevention, Emerging Infectious Diseases Journal, full text: <cite cite="http://www.cdc.gov/eid/content/17/2/180.htm">Human Infections with Non-O157 STEC, Switzerland | CDC EID</cite>. Abstract, edited.]
Volume 17, Number 2?February 2011
Research
Human Infections with Non-O157 Shiga Toxin?producing Escherichia coli, Switzerland, 2000?2009
Ursula K?ppeli, Herbert H?chler, Nicole Giezendanner, Lothar Beutin, and Roger Stephan
Author affiliations: University of Zurich, Zurich, Switzerland (U. K?ppeli, H. H?chler, N. Giezendanner, R. Stephan); and Federal Institute for Risk Assessment, Berlin, Germany (L. Beutin)
Abstract
We characterized 97 non-O157 Shiga toxin (stx)?producing Escherichia coli strains isolated from human patients during 2000?2009 from the national reference laboratory in Switzerland. These strains belonged to 40 O:H serotypes; 4 serotypes (O26:H11/H?, O103:H2, O121:H19, and O145:H28/H?) accounted for 46.4% of the strains. Nonbloody diarrhea was reported by 23.2% of the patients, bloody diarrhea by 56.8%. Hemolytic uremic syndrome developed in 40.0% of patients; serotype O26:H11/H? was most often associated with this syndrome. Forty-five (46.4%) strains carried stx2 genes only, 36 strains (37.1%) carried stx1, and 16 (16.5%) strains carried stx1 and stx2. Genes encoding enterohemolysin and intimin were detected in 75.3% and 70.1% of the strains, respectively. Resistance to >1 antimicrobial agent was present in 25 isolates. High genetic diversity within strains indicates that non-O157 stx?producing E. coli infections in Switzerland most often occurred as single cases.
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[Source: US Centers for Disease Control and Prevention, Emerging Infectious Diseases Journal, full text: <cite cite="http://www.cdc.gov/eid/content/17/2/180.htm">Human Infections with Non-O157 STEC, Switzerland | CDC EID</cite>. Abstract, edited.]
Volume 17, Number 2?February 2011
Research
Human Infections with Non-O157 Shiga Toxin?producing Escherichia coli, Switzerland, 2000?2009
Ursula K?ppeli, Herbert H?chler, Nicole Giezendanner, Lothar Beutin, and Roger Stephan
Author affiliations: University of Zurich, Zurich, Switzerland (U. K?ppeli, H. H?chler, N. Giezendanner, R. Stephan); and Federal Institute for Risk Assessment, Berlin, Germany (L. Beutin)
Abstract
We characterized 97 non-O157 Shiga toxin (stx)?producing Escherichia coli strains isolated from human patients during 2000?2009 from the national reference laboratory in Switzerland. These strains belonged to 40 O:H serotypes; 4 serotypes (O26:H11/H?, O103:H2, O121:H19, and O145:H28/H?) accounted for 46.4% of the strains. Nonbloody diarrhea was reported by 23.2% of the patients, bloody diarrhea by 56.8%. Hemolytic uremic syndrome developed in 40.0% of patients; serotype O26:H11/H? was most often associated with this syndrome. Forty-five (46.4%) strains carried stx2 genes only, 36 strains (37.1%) carried stx1, and 16 (16.5%) strains carried stx1 and stx2. Genes encoding enterohemolysin and intimin were detected in 75.3% and 70.1% of the strains, respectively. Resistance to >1 antimicrobial agent was present in 25 isolates. High genetic diversity within strains indicates that non-O157 stx?producing E. coli infections in Switzerland most often occurred as single cases.
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