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Emergence of Monkeypox ? West and Central Africa, 1970?2017

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  • Emergence of Monkeypox ? West and Central Africa, 1970?2017

    Source: https://www.cdc.gov/mmwr/volumes/67/...cid=mm6710a5_e



    Emergence of Monkeypox ? West and Central Africa, 1970?2017
    Weekly / March 16, 2018 / 67(10);306?310

    Kara N. Durski, MPH1; Andrea M. McCollum, PhD2; Yoshinori Nakazawa, PhD2; Brett W. Petersen, MD2; Mary G. Reynolds, PhD2; Sylvie Briand, MD, PhD1; Mamoudou Harouna Djingarey, MD3; Victoria Olson, PhD2; Inger K. Damon, MD, PhD2; Asheena Khalakdina, PhD1 (View author affiliations)
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    Summary

    What is already known about this topic?

    Human monkeypox is a viral zoonosis that occurs in West Africa and Central Africa. Most cases are reported from Democratic Republic of the Congo. The disease causes significant morbidity and mortality, and no specific treatment exists.

    What is added by this report?

    Nigeria is currently experiencing the largest documented outbreak of human monkeypox in West Africa. During the past decade, more human monkeypox cases have been reported in countries that have not reported disease in several decades. Since 2016, cases have been confirmed in Central African Republic (19 cases), Democratic Republic of the Congo (>1,000 reported per year), Liberia (two), Nigeria (>80), Republic of the Congo (88), and Sierra Leone (one). The reemergence of monkeypox is a global health security concern.

    What are the implications for public health practice?

    A recent meeting of experts and representatives from affected countries identified challenges and proposed actions to improve response actions and surveillance. The World Health Organization and CDC are developing updated guidance and regional trainings to improve capacity for laboratory-based surveillance, detection, and prevention of monkeypox, improved patient care, and outbreak response.

    The recent apparent increase in human monkeypox cases across a wide geographic area, the potential for further spread, and the lack of reliable surveillance have raised the level of concern for this emerging zoonosis. In November 2017, the World Health Organization (WHO), in collaboration with CDC, hosted an informal consultation on monkeypox with researchers, global health partners, ministries of health, and orthopoxvirus experts to review and discuss human monkeypox in African countries where cases have been recently detected and also identify components of surveillance and response that need improvement. Endemic human monkeypox has been reported from more countries in the past decade than during the previous 40 years. Since 2016, confirmed cases of monkeypox have occurred in Central African Republic, Democratic Republic of the Congo, Liberia, Nigeria, Republic of the Congo, and Sierra Leone and in captive chimpanzees in Cameroon. Many countries with endemic monkeypox lack recent experience and specific knowledge about the disease to detect cases, treat patients, and prevent further spread of the virus. Specific improvements in surveillance capacity, laboratory diagnostics, and infection control measures are needed to launch an efficient response. Further, gaps in knowledge about the epidemiology and ecology of the virus need to be addressed to design, recommend, and implement needed prevention and control measures...
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