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Uganda declares Ebola Virus Disease outbreak (SEBOV) - 20 Sept 2022 - Outbreak is over

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  • #31
    WEEKLY BULLETIN ON OUTBREAKS
    AND OTHER EMERGENCIES

    Week 39: 19 - 25 September 2022
    Data as reported by: 17:00; 25 September 2022

    ...

    Ebola Virus Disease caused by Sudan virus in Uganda

    36 cases
    23 Deaths
    64.0% CFR


    EVENT DESCRIPTION

    In line with the International Classification of Disease for
    filoviruses (ICD-11) released in May 2019, outbreaks of a disease
    caused by the Sudan ebolavirus are named Sudan Virus Disease
    (SVD) outbreaks. This is the first outbreak of SVD since the new
    classification.

    On 20 September 2022, the Uganda Ministry of Health officially
    declared an outbreak of SVD. The index case is a 24-year-old male
    residing in Ngabano village, Madudu Sub-County in Mubende
    District. His symptom onset was on 11 September, when he
    developed high grade fever, tonic convulsions, blood-stained
    vomit and diarrhoea, loss of appetite, pain while swallowing,
    chest pain, dry cough and bleeding in the eyes.

    He therefore attended two private clinics successively between
    11-13 and 13-15 September without improvement. He was then
    referred to the Mubende Regional Referral Hospital (RRH) on 15
    September where he was immediately isolated as a suspected
    case of viral haemorrhagic fever. A sample was collected on 17
    September and sent to the Uganda Virus Research Institute in
    Kampala where RT- PCR tests conducted were positive for SVD
    on 19 September. On the same day, the patient died.

    According to ongoing investigations, a series of unexplained
    community deaths from an unknown illness, and sudden deaths
    appearing in Madudu and Kiruma Sub-Counties of Mubende
    District were reported in the first two weeks of September.

    Preliminary findings revealed six other suspected deceased cases
    with ages ranging from 10 days to 56 years recorded at Mubende
    RRH and a few private clinics in Kiruma (five cases) and Madudu
    (one case) sub-counties of Mubende district. These fatal cases
    include four members of one family and one health care worker.

    The deaths occurred between 1–15 September. The cases were
    not isolated while in treatment and they were traditionally buried
    through gathering ceremonies without specific infection control
    measures.

    As of 25 September 2022, a total of 36 cases have been reported
    including 18 confirmed and 18 probable cases. Twenty-three
    deaths have been recorded, including five confirmed, for an
    overall case fatality ratio (CFR) of 64% and 28% among confirmed
    cases. Women (67%) are twice more affected than men, and 37%
    of cases are aged below 20 years.

    Three Districts have so far been affected: Mubende, the epicentre
    with 32 cases, Kyegegwa with three confirmed casesand
    Kassanda withone confirmed case. Thirty-five patients are
    currently in admission including 22 suspected and 13 confirmed
    cases. A total of 399 contacts have been listed with a 26% followup
    rate in the past 24hrs.

    PUBLIC HEALTH ACTIONS

    Coordination

    A National Task Force has been established by the MoH, with
    WHO providing technical support, and daily meetings are
    being held.

    A national SVD response plan has been approved to guide
    response activities.

    An Incidence Management Team (IMT) has been activated
    at national level and the MoH Incident Commander has been
    deployed to Mubende District to support response efforts
    locally. A situation room has been established at Mubende
    RRH to support the coordination.

    District Task Force (DTFs) meetings have been activated
    in Mubende, Sembabule, Kyankwanzi, Kampala, Mityana,
    Kyegegwa, Gomba, Kiboga, Kassanda, Kazo, Kakumiro and
    Kibaale.

    Rapid Response Teams have been deployed to the 12
    districts to activate the response mechanisms, conduct risk
    assessments and support development of district response
    plans.

    Surveillance and Laboratory

    Epidemiological investigations, contact tracing, and active
    case finding in the districts are ongoing. A total of 399
    contacts have already been listed with 176 over the past
    24hrs; 104 contacts (26%) have been followed-up. In
    addition, an alert desk has been established in Mubende
    District: 24 alerts have been received in the past 24hrs, 11
    (46%) of which have been investigated.

    The Mubende surveillance sub-committee has been activated
    and briefed on its role.

    Eighteen supervisors have been trained in contact tracing,
    alert management, case investigation, event-based
    surveillance, and data management.

    Additional epidemiologists have been deployed to support
    the neighbouring districts, and surveillance tools have been
    printed and distributed.

    Laboratory experts have been deployed from national level
    and capacity building support, sample collection, packaging,
    and transportation is ongoing.

    Two Bio-fire mobile laboratory equipment and assorted
    accessory equipment have been deployed to Mubende, with
    a capacity of 20 samples to be tested per day. In an event of
    increased number of samples, a higher version of Bio-fire
    will be deployed.

    Case management and infection, prevention and control (IPC)

    Management of patients (suspected and confirmed) is
    ongoing at Mubende RRH. A total of 35 patients are currently
    in admission at Mubende RRH.

    The case management pillar has deployed experts for IPC as
    well patient care and treatment to support Mubende RRH.
    Mortuary attendants have been trained in safe and dignified
    burial practices.

    WHO and other Partners are supporting the MoH in
    establishing an Ebola Treatment Unit at Mubende RRH.
    IPC teams are supporting capacity building of health workers
    in IPC and the establishment of triage in all healthcare
    facilities in affected districts.

    Risk communication

    Information, Education and Communication materials have
    been reviewed and are being disseminated to affected and
    high-risk districts, especially in schools, churches, and
    communities at the epicentre of the outbreak. Around 1000
    students and teachers of five schools have been sensitized
    in Madudu sub-country.

    All four radio stations in Mubende have been engaged and
    initiated the airing of WHO-sponsored messages and talk
    shows.

    Logistics

    Three Ebola disease kits and an isolation tent have been
    received at the Mubende RRH to support case management,
    as well as IPC items and supplies.

    Fuel cards have been provided to support the mobility of
    response teams on ground.

    SITUATION INTERPRETATION

    The source and extent of this outbreak remain to be determined.
    From available information, it is possible that the event started
    three weeks ago and is already generating secondary or tertiary
    cases. Also, the outbreak was detected among individuals living
    around an active local gold mine with a highly mobile population.
    Patients presented at different facilities yielding suboptimal IPC
    practices where they died and were subsequently traditionally
    buried with large gathering ceremonies. In this context, the
    possibility of spread to other districts and importation of cases
    to neighbouring countries cannot be ruled out.
    Therefore, in
    the absence of specific vaccines and therapeutics, the control
    of this outbreak will solely rely on early detection, isolation and
    management of cases, optimal IPC measures, and robust risk
    communication and community engagement.

    https://extranet.who.int/iris/restri...1925092022.pdf
    "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
    -Nelson Mandela

    Comment


    • #32
      Uganda rules out Ebola lockdown

      Thursday, September 29, 2022
      By Monitor Team
      ...
      Uganda's President Museveni on Wednesday ruled out imposing a lockdown to contain the highly contagious Ebola virus, saying the country had the capacity to contain the outbreak.
      ...
      "We decided that we shall not have lockdowns. It is not necessary," Museveni said.

      "Government has capacity to control this outbreak as we have done before. There is no need for anxiety, no restrictions of movements, closure of schools places of worships, markets as of now."
      ...
      Six health workers were receiving treatment after testing positive for Ebola following exposure to the first victim, Museveni said.
      ...

      https://www.monitor.co.ug/uganda/new...ckdown-3966074

      Comment


      • #33

        WHO African Region
        @WHOAFRO

        UPDATE: #Ebola in #Uganda🇺🇬 Situation Report (28/09/22)

        ▪️ 50 cases (31 confirmed, 19 probable)
        ▪️ 2 recoveries in past 24 hours
        ▪️ 24 deaths ( 6 confirmed, 18 probable)
        ▪️ 414 contacts identified
        ▪️ 3 districts affected (Mubende, Kassanda, Kyegegwa)



        7:35 AM · Sep 29, 2022·Twitter Web App
        "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
        -Nelson Mandela

        Comment


        • #34
          Republic of Uganda - District affected - Ebola contact cases as of September 28th, 2022

          29 Sep 2022
          By Médecins Sans Frontières
          ...
          ebola.jpg

          https://reliefweb.int/map/uganda/rep...mber-28th-2022

          Comment


          • #35
            Dr. Jane Ruth Aceng Ocero
            @JaneRuth_Aceng

            I regret to announce that we have lost our first doctor, Dr Mohammed Ali, a Tanzanian National, 37yr old Male today at 3:15am. He tested positive of Ebola on Sept 26, 2022 and died while receiving treatment at Fort Portal RRH, Isolation facility ( JMedic).




            1:03 AM · Oct 1, 2022·Twitter for iPhone

            --------------------------------------

            Dr. Jane Ruth Aceng Ocero
            @JaneRuth_Aceng
            ·

            I condole with his family, medical fraternity, KIU university and the people of Tanzania.

            Dr. Ali is the first Doctor, and second health worker to have succumbed to Ebola. The first was a midwife from St Florence Clinic, a probable case, because she died before testing.
            ...
            1:04 AM · Oct 1, 2022·Twitter for iPhone


            --------------------------------------------------------------------

            Tanzanian doctor dies from Ebola Virus in UgandaPublished

            58 mins ago on October 1, 2022By Akanimoh Etim

            A Tanzanian medical doctor, Mohammed Ali, has died in Uganda after being infected with the Ebola virus, the Association of Surgeons of Uganda (ASU) announced on Saturday.
            ...
            The 37-year-old Ali who was pursuing a Master of Medicine in Surgery course at Kampala International University, became the second medical personnel to succumb to Ebola since the renewed outbreak last month, the ASU said.

            In a statement by Uganda’s Ministry of Health, it was not clear how Ali got infected but his death came after the Ministry announced that seven more deaths had been recorded on Friday.
            ...
            “So far, at least eight health workers have tested positive for EHVF, including intern doctors and senior house officer (all trainees) who were stationed at the centre of the outbreak at Mubende Regional Referral Hospital, according to Uganda Medical Association (UMA),” the Minister added.

            https://africanewswatch.com/2022/10/...rus-in-uganda/

            "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
            -Nelson Mandela

            Comment


            • #36
              Testing trouble adds to disorder in Uganda’s Ebola response

              By RODNEY MUHUMUZA
              today
              ...
              Thirty-five Ebola cases have been confirmed since Sept. 20, including six health workers, and a doctor is among at least seven confirmed deaths.

              Only one government-run facility, located 180 kilometers (111 miles) away in Entebbe, is equipped to test for Ebola, and officials sometimes wait up to 48 hours before results come in.
              ...
              Health authorities are still investigating the source of the current outbreak, which likely began in August, Ugandan President Yoweri Museveni said in a televised address earlier this week. It was a surprising admission for an East African country that’s often cited for its leadership in fighting disease outbreaks.

              Hamstrung by testing difficulties from the beginning, the initial response was sometimes chaotic as health officials raced to corral contacts and set up an isolation unit, according to health workers and others on the ground.

              Some health workers said they felt helpless when ambulances delayed in picking up patients possibly suffering from Ebola. A woman whose farmworker died of Ebola recalled being taken into an isolation unit where some quarantined patients started to bleed, worrying those without symptoms who knew they risked infection.
              ...
              Ugandan authorities had documented 427 known contacts by Friday. But some taken into quarantine escaped and remain at large, complicating the tracing work that’s key to preventing a widening outbreak.
              ...
              The hospital made “the biggest alarm you can ever think of,” he said, and soon efforts were underway to set up an isolation unit with the help of Doctors Without Borders. That unit was still being set up 10 days after the outbreak had been declared.
              ...
              https://apnews.com/article/health-af...fbee8c62ec6fa3
              "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
              -Nelson Mandela

              Comment


              • #37
                WHO African Region
                @WHOAFRO

                UPDATE: #Ebola in #Uganda🇺🇬 Situation Report (29/09/22)

                ▪️ 54 cases (35 confirmed, 19 probable)
                ▪️ 2 recoveries
                ▪️ 25 deaths (7 confirmed, 18 probable)
                ▪️ 517 contacts identified
                ▪️ 4 districts affected (Mubende, Kassanda, Kyegegwa, Kagadi)



                4:00 AM · Oct 1, 2022·Twitter Web App
                "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
                -Nelson Mandela

                Comment


                • #38
                  I moved one post about a suspected case in Kenya to this thread:

                  https://flutrackers.com/forum/forum/...ted-ebola-case

                  Comment


                  • #39

                    Scientists race to test vaccines for Uganda’s Ebola outbreak

                    As deaths climb, researchers once again scramble to launch trials during a crisis

                    29 SEP 2022 1:05 PM

                    BY JON COHEN

                    A multipronged international effort has begun to pull out all the stops to launch trials of experimental Ebola vaccines in Uganda, which declared an outbreak of the deadly disease on 20 September. According to the most recent World Health Organization (WHO) update, Uganda has had 18 confirmed and 18 suspected cases of Ebola, including 23 deaths—an unusually high case fatality rate of 64%. A trial of a vaccine candidate that’s farthest along in development could launch before the end of next month.

                    Proven vaccines exist for Zaire ebolavirus, which has led to a dozen outbreaks in the neighboring Democratic Republic of the Congo (DRC) and was responsible for the massive Ebola epidemic in West Africa in 2014. But those vaccines cannot control this outbreak because it’s being driven by a distant viral relative known as Sudan ebolavirus, which last caused an outbreak, also in Uganda, in 2012. The Zaire and Sudan ebolaviruses “are not variants and they’re not strains—they’re different viruses,” says Nancy Sullivan, who heads biodefense research at the National Institute of Allergy and Infectious Diseases (NIAID) and has collaborated on Ebola vaccine studies. Researchers have long recognized that the world badly needs a Sudan ebolavirus vaccine: In 2016, Science published a survey of 50 leading vaccine researchers who ranked the Sudan ebolavirus vaccine as the number one R&D priority based on feasibility and need. But vaccinemakers have had little financial incentive to produce one. Even if the current trial succeeds, producing enough doses fast enough will be a challenge.

                    Three experimental Sudan ebolavirus vaccines have been tested in human studies, but because outbreaks are so rare, they have not had a real-world test. “We are moving really fast this time and people are really willing to work to get these vaccines on the ground,” says Ana Maria Henao-Restrepo, a WHO vaccine specialist who is coordinating discussions between the Ugandan government and stakeholders elsewhere in the world, including vaccine manufacturers, funders, and nongovernmental organizations.

                    The farthest ahead is a candidate that the pharmaceutical giant GlaxoSmithKline began to develop during the West African outbreak; GSK donated the license for it to the nonprofit Sabin Vaccine Institute in 2019. The single-dose vaccine contains the gene for the surface protein of the virus stitched into a harmless chimpanzee adenovirus (ChAd), which serves as a shuttle to deliver the payload into cells. The U.S. government’s Biomedical Advanced Research and Development Authority in 2019 awarded Sabin a $128 million contract to develop the product, and the candidate has worked well in monkey studies and small-scale clinical trials conducted by NIAID’s Vaccine Research Center.

                    Henao-Restrepo says WHO organized two rounds of consultations this week with vaccine developers and others, which led to a unanimous agreement that the Sabin candidate should be first in line for a Ugandan trial. Ugandan health officials are now evaluating a draft proposal for this trial. If all goes well, Henao-Restrepo says a study could begin before the end of October.

                    NIAID’s Richard Koup, acting director of the vaccine research center, says it has 100 doses of the vaccine and has made them available to Uganda. Another 40,000 doses exist in bulk form that need to be put in vials. The Coalition for Epidemic Preparedness Innovations (CEPI), a nonprofit that supports R&D for vaccines, is working with Sabin to find a manufacturer who can do what’s called “fill and finish.” ...

                    https://www.science.org/content/arti...ebola-outbreak

                    Comment


                    • #40
                      Ministry of Health- Uganda

                      @MinofHealthUG

                      #EbolaOutbreakUG update as of 2 October 2022.


                      7:42 AM · Oct 3, 2022·Twitter for iPhone
                      "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
                      -Nelson Mandela

                      Comment


                      • #41
                        Health officials explain Bunyangabu Ebola case

                        Tuesday, October 04, 2022

                        By Alex Ashaba

                        Health officials from Bunyangabu District have said the new Ebola virus disease case is of a fourth-year medical student of Kampala International University.

                        The District Health Officer, Dr Richard Obeti, said the patient, who is being managed at Fort Portal Regional Referral Hospital was among the health workers who were attending to Ebola patients at Mubende Hospital.

                        Dr Obeti said the patient was in contact with Dr Mohammed Ali, who succumbed to Ebola on Saturday morning at Fort Portal Regional Referral Hospital.

                        He said on September 24, the student travelled from Mubende to his village in Gatyanga A1 in Rwimi Town Council, Bunyangabu District.
                        ...

                        https://www.monitor.co.ug/uganda/new...a-case-3972308
                        "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
                        -Nelson Mandela

                        Comment


                        • #42
                          Ebola in Uganda



                          Alert - Level 2, Practice Enhanced Precautions



                          Key points
                          • The Ministry of Health of Uganda has declared an Ebola outbreak in several districts in Uganda (see map). Avoid non-essential travel to these regions.
                          • This outbreak has been linked to the Sudan ebolavirus. No vaccines or therapeutics have been approved for prevention or treatment of the Sudan ebolavirus.
                          • Travelers should avoid contact with sick people and avoid contact with blood or body fluids from all people.
                          • Travelers should avoid contact with dead bodies, including participating in funeral or burial rituals.
                          • Travelers should isolate immediately and seek medical care if they develop signs and symptoms like fever, muscle pain, sore throat, diarrhea, weakness, vomiting, stomach pain, or unexplained bleeding or bruising during or for up to 21 days after travel. Travelers who develop symptoms after arriving in the United States should follow additional recommendations.
                          • Organizations sending US-based healthcare or emergency response workers to the outbreak area should follow CDC recommendations to ensure their workers are healthy when they return to the United States.
                          • CDC and the World Health Organization (WHO) are working with local health authorities to identify sources of transmission, conduct case investigations, and strengthen local laboratory capacity.
                          Traveler InformationClinician Information

                          Map: Uganda (see larger map)
                          What is Ebola?

                          Ebola virus disease (also known as Ebola hemorrhagic fever) is a rare and deadly disease that periodically causes outbreaks in several African countries. It is spread by contact with blood or body fluids of a person infected with Ebola virus. It is also spread by contact with contaminated objects or infected animals.

                          Symptoms include fever, headache, muscle pain, weakness, diarrhea, vomiting, stomach pain, and unexplained bleeding or bruising. The death rate for Ebola virus disease ranges from 25% to 90%.


                          Page last reviewed: October 04, 2022
                          Content source: [URL="https://www.cdc.gov/ncezid/index.html"]National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)

                          https://www.cdc.gov/ncezid/dgmq/index.html"]Division of Global Migration and Quarantine (DGMQ)

                          https://wwwnc.cdc.gov/travel/notices...bola-in-uganda

                          Comment


                          • #43
                            Source: https://english.alarabiya.net/News/w...m-virus-to-10-


                            Health worker in Uganda dies of Ebola, raising toll from virus to 10
                            AFP, Kampala
                            Published:05 October ,2022: 11:48 AM GST Updated:05 October ,2022: 11:59 AM GST

                            Uganda on Wednesday confirmed the death of a health worker from Ebola, bringing the total number of fatalities from the highly contagious virus to 10.

                            The latest death comes two weeks after the government declared an outbreak.

                            For the latest headlines, follow our Google News channel online or via the app .

                            Health Minister Jane Ruth Aceng Ocero said that a 58-year-old anesthetic officer had died of Ebola early on Wednesday.

                            “The late Margaret is the fourth health worker we have lost in the current Ebola outbreak,” the minister said on Twitter, following the deaths of a Tanzanian doctor, a health assistant, and a midwife...

                            Comment


                            • #44

                              Dr. Jane Ruth Aceng Ocero

                              @JaneRuth_Aceng
                              ·
                              7h
                              The late Margaret is the 4th health worker we have lost in the current Ebola outbreak after the probable case of the midwife, Dr. Ali and the health assistant in Kagadi District. May their souls rest in eternal peace.
                              Quote Tweet

                              Dr. Jane Ruth Aceng Ocero
                              @JaneRuth_Aceng
                              ·
                              7h
                              I regret to announce the passing of another Health worker, Ms. Nabisubi Margaret, an anesthetic officer. The 58 year old succumbed to Ebola at 4.33am this morning at Fort Portal Hospital (JMedic) after battling the disease for 17 days.
                              22
                              98
                              152
                              Dr. Jane Ruth Aceng Ocero

                              @JaneRuth_Aceng
                              ·
                              7h
                              I regret to announce the passing of another Health worker, Ms. Nabisubi Margaret, an anesthetic officer. The 58 year old succumbed to Ebola at 4.33am this morning at Fort Portal Hospital (JMedic) after battling the disease for 17 days.
                              512
                              1,002
                              2

                              Comment


                              • #45
                                WHO Director-General's opening remarks at the media briefing – 5 October 2022

                                5 October 2022

                                Good morning, good afternoon, and good evening.

                                First to Uganda, where WHO is continuing to support the government to respond to an outbreak of Ebola disease in four districts.

                                So far, 63 confirmed and probable cases have been reported, including 29 deaths.

                                Ten health workers have been infected, and four have died.


                                Four people have recovered and are receiving follow-up care.

                                WHO has released US$2 million from our Contingency Fund for Emergencies, and we’re working with our partners to support the Ministry of Health by sending additional specialists, supplies, and resources.

                                When there is a delay in detecting an Ebola outbreak, it is normal for cases to increase steadily at the beginning and then decrease as life-saving interventions and outbreak control measures are implemented.

                                The vaccines used successfully to curb recent Ebola outbreaks in the Democratic Republic of the Congo are not effective against the type of Ebola virus that is responsible for this outbreak in Uganda.

                                However, several vaccines are in various stages of development against this virus, two of which could begin clinical trials in Uganda in the coming weeks, pending regulatory and ethics approvals from the Ugandan government.


                                ===...
                                https://www.who.int/news-room/speech...5-october-2022
                                "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
                                -Nelson Mandela

                                Comment

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