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China - Original COVID-19 coronavirus news thread: weeks 1 - 4 (December 30, 2019 - January 25, 2020)

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  • Source: https://www.cnn.com/2020/01/22/healt...ner/index.html

    Snakes could be the source of the Wuhan coronavirus outbreak
    By Haitao Guo, Guangxiang "George" Luo and Shou-Jiang Gao, The Conversation
    Updated 7:26 PM ET, Wed January 22, 2020

    (CNN)Snakes -- the Chinese krait and the Chinese cobra -- may be the original source of the newly discovered coronavirus that has triggered an outbreak of a deadly infectious respiratory illness in China this winter.

    The many-banded krait (Bungarus multicinctus), also known as the Taiwanese krait or the Chinese krait, is a highly venomous species of elapid snake found in much of central and southern China and Southeast Asia...

    Comment


    • nCoV’s relationship to bat coronaviruses & recombination signals (no snakes)

      Novel 2019 coronavirus
      Jan 22
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      Jan 22
      36m ago
      david.l.robertson
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      With Xiaowei Jiang at XJTLU we’ve carried out a preliminary evolutionary analysis to characterise the evolutionary origins of the Wuhan virus, nCoV. Focus of our analysis is on the Wuhan-Hu-1 virus (accession no. MN908947, released on GenBank by Shanghai Public Health Clinical Center and School of Public Health, Fudan University, Shanghai, China) as all nCoV cluster together so will share the same evolutionary ancestry. It’s clear from phylogenetic analysis the new human virus is most closely related to bat coronaviruses in the Betacoronaviruses genera. While this is apparent from both the previously reported BLAST and full-genome phylogenetic analysis the closest related bat viruses (CoVZC45 and CoVZXC21) are in fact recombinants with shared breakpoints either side of ORF1b:


      nCoV-recombination-analysis
      nCoV-recombination-analysis1528?1138 469 KB


      The phylogenetic clustering of the Wuhan-Hu-1 virus is consistently as a sister group to the SARS-related bat coronaviruses. Interestingly, a third bat coronavirus (Longquan_140) is a recombinant involving the Wuhan virus lineage in part of ORF1a.


      1680-3014
      1680-3014692?540 50.6 KB


      This analysis has detected three bat coronavirus recombinants (two with shared breakpoints) involving the nCoV lineage indicating greater diversity in the Chinese Sarbecovirus group than previously appreciated. The clustering of the related Sarbecovirus viruses from Kenya and Europe suggest the Wuhan virus is still part of the Sabecovirus sub-genre, and these recombination events probably occurred in bats. Although. given the propensity of coronaviruses to switch hosts, involvement of another species cannot be discounted. There is also a very good chance that a non-bat intermediate species is responsible for the beginning of the current outbreak in Wuhan. Given the tight clustering of the nCoV viruses in phylogenetic trees it seems most likely one event has occurred.

      Several of these bat coronaviruses have been previously detected to be recombinant under-scoring the importance of doing appropriate analysis when analysing these viruses using phylogenetic methods. Recombination, in this case between divergent coronaviruses circulating in bats, violates our assumption of a single evolutionary tree and so needs to be considered carefully when inferring coronavirus evolution from complete genome alignments. We’re looking into the patterns of breakpoints to see if there’s any clues to the significance (or not) of these recombination events.

      We’d like to thank the researchers and health professionals for making the nCoV data available. Credit also needs to be given to the surveillance projects for generating the data that is now available for comparison and to the software developers for making the tools we’ve used freely available: FigTree, available at: http://tree.bio.ed.ac.uk/software/figtree/; 9 GARD, available at http://www.hyphy.org 5; MAFFT, available at https://mafft.cbrc.jp/alignment/software/; 4 PhyML, available at http://www.atgc-montpellier.fr/phyml/; 5 and RDP4, available at http://www.atgc-montpellier.fr/phyml/ 5.

      http://virological.org/t/ncovs-relat...-no-snakes/331
      Twitter: @RonanKelly13
      The views expressed are mine alone and do not represent the views of my employer or any other person or organization.

      Comment


      • Source: http://news.china.com.cn/txt/2020-01...t_75642508.htm

        China announces 丨 3 new cases of pneumonia confirmed by new coronavirus infection in Guangxi
        Published: 2020-01-23 08:39:04 | Source: China Network | Author: Wu Jia Tong

        China Net, January 23rd According to the Health and Health Committee of the Guangxi Zhuang Autonomous Region, as of 1 am on the 23rd, three new cases of pneumonia confirmed by a new coronavirus infection were reported in Guangxi.

        Patient Xu, male, 63 years old, a citizen of Wuhan, developed symptoms such as cough and fever on the 14th, arrived in Beihai City on the 20th, went to the local hospital for treatment on the 21st, and was transferred to Beihai designated hospital for isolation and treatment on the 22nd. Coronavirus positive.

        Patient Jingmou, female, 62 years old, a citizen of Wuhan. She developed symptoms such as low fever and cough on January 9th. She went to Beihai on the 15th and went to a designated hospital in Beihai on the 21st and was hospitalized. On the 22nd, the laboratory tested positive for new coronavirus .

        Patient Huang, male, 49 years old, living in Wuhan for a long time, went to Liuzhou from January 20, and developed fever symptoms on January 21, and was admitted to Liuzhou designated hospital for isolation and treatment. On January 22, the laboratory tested positive for a new coronavirus nucleic acid. .

        At present, Guangxi Zhuang Autonomous Region has reported a total of 5 confirmed cases of pneumonitis with new coronavirus infection (3 in Beihai, 1 in Wuzhou, and 1 in Liuzhou), all of which have a history of residence, work or contact history in Wuhan. All patients were treated in isolation at designated hospitals, and a total of 94 close contacts were receiving medical observation. From January 21 to 22, 17 suspected cases were ruled out by laboratory tests in the autonomous region.

        (Edit: Wu Jiayu)

        Comment


        • Source: http://www.hlj.chinanews.com/hljnews...123/53867.html



          Google translation:

          Mudanjiang City confirms 1 confirmed case of imported pneumococcal infection
          News Source: Heilongjiang Daily | Release Date Time: January 23, 2020 08:43

          1On January 23, 2020, the National Health and Health Commission confirmed the first confirmed case of pneumonia due to imported new coronavirus infection in Heilongjiang Province. The patient was a 69-year-old male from Mudanjiang. After returning from Wuhan City to Mudanjiang City on January 12, she was isolated and treated at Mudanjiang Second Hospital due to fever, cough, sputum and fatigue. At present, the patient is seriously ill and is now in full care. The patient's close contacts are under medical observation and are currently normal.

          Mudanjiang Municipal Health and Health Committee

          January 23, 2020
          [Edit: Li Xiangmei]

          Comment


          • Source: http://industry.caijing.com.cn/20200123/4640261.shtml

            Google translation:

            Rizhao City, Shandong Province admitted to two patients with preliminary detection of novel coronavirus nucleic acid
            This article comes from CCTV News 2020-01-23 08:56:58

            In the early morning of January 23, the official website of Rizhao City Health and Health Committee released the news: On January 22, Rizhao City treated two patients, one from Wuhan and one who was a close contact with a confirmed case. After preliminary testing in the laboratory, both were positive for the new coronavirus nucleic acid, and the patient specimens have been sent to the provincial professional institutions for review in accordance with regulations. Once the diagnosis is confirmed, they will be announced to the public in time. The Rizhao Municipal Health Committee is implementing relevant measures in accordance with regulations.

            (CCTV reporter Dou Xiaolei)



            Comment


            • Source: http://news.cnstock.com/news,bwkx-202001-4482057.htm

              Google translation:

              7 new cases of pneumonia confirmed by new coronavirus infection in Shanghai
              2020-01-23 09:04:52 Source: Shanghai Securities News ? China Securities Network Author:

              Shanghai Securities News China Securities News According to Shanghai ’s WeChat public account news on January 23, the Shanghai Health and Medical Commission announced this morning (23) that from January 22 to 04:00, 7 new cases of coronavirus were added in Shanghai. The confirmed cases of infected pneumonia have been treated in isolation at designated hospitals. Among the patients, 4 were males and 3 were females, all of which were associated with Wuhan epidemiology. Among them, a 88-year-old male patient with cardiopulmonary insufficiency was in critical condition. Close contacts are receiving medical observation.

              As of 24:00 on January 22, a total of 16 confirmed cases were found in Shanghai, of which one was critically ill and the remaining 15 were in stable condition. Another 22 suspected cases are under investigation.

              Comment


              • Macao announces 2nd case:


                Government report -

                Macao confirmed second case of new coronavirus in Wuhan

                source: Department of Health (SS) Release date: January 23, 2020 09:47 The Health Bureau said that Macao confirmed the second case of Wuhan's new coronavirus. The 66-year-old male, a tourist from Wuhan, was detected by the health bureau quarantine staff as having fever and temperature when entering Macau through the checkpoint yesterday (22). At 38.7 degrees, he was rushed to the special emergency department of Earl General Hospital for further examination. After testing, he tested positive for the new coronavirus. Details of the confirmed case will be announced at a press conference at 11:00 this morning.

                https://www.gov.mo/zh-hant/news/314906/

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                • Three new cases of pneumonia confirmed by new coronavirus infection in Sichuan

                  Published: 2020-01-23 10:41:34 | Source: China News | Author: Anonymous
                  More News Enter News Center

                  China News Service, January 23rd. According to the official Weibo of the Sichuan Provincial Health and Health Committee on the 23rd, three new cases of pneumonia confirmed by imported new coronavirus infection have been added in Sichuan Province.

                  Patient Yang, a 50-year-old male, returned to Chengdu from Wuhan on January 13. On January 18, he went to a hospital in Chengdu for fever, cough, dyspnea and other symptoms, and the hospital was admitted for isolation.

                  Patient Wu, a 48-year-old male, returned to Chengdu from Wuhan on January 10. On January 18, he went to a hospital in Chengdu because of fever, and the hospital was admitted for isolation.

                  Patient Du, a 36-year-old male, arrived in Wuhan from January 17th. On January 18, he was treated in a physical clinic in Dazhou due to fever and fatigue. He went to a hospital on the 20th, and the hospital was isolated.

                  In accordance with the "Pneumonitis Diagnosis and Treatment Program for New Coronavirus Infection" (trial version 2), based on the clinical manifestations of the cases, combined with epidemiological history and laboratory test results, the provincial expert group confirmed that these 3 cases were imported new coronavirus Infected pneumonia cases.

                  As of 8:00 on January 23, Sichuan has reported 8 confirmed cases of pneumonitis with new coronavirus infection (including 4 in Chengdu, 2 in Mianyang, 1 in Guang'an, and 1 in Dazhou), and 4 suspected cases (2 in Chengdu). , Suining 1 case, Guangan 1 case), the above 12 people were treated in designated medical institutions, the condition is stable. Medical observations have been carried out on close contacts, and currently there are no abnormalities such as fever.

                  http://news.china.com.cn/2020-01/23/...t_75643380.htm

                  Comment


                  • Epidemic situation of new coronavirus infection in Guangdong Province on January 23, 2020


                    Time: 2020-01-23 10:45:58 source: this website
                      At 04:00 on January 22, 2020, Guangdong Province reported 6 new confirmed cases of pneumonia due to new coronavirus infection. among them:

                      Zhongshan and Zhaoqing each had 1 case as the first confirmed case. Among the newly confirmed cases in the other two cities, 3 were in Guangzhou and 1 in Shenzhen.

                      As of 24:00 on January 22, Guangdong Province had reported a total of 32 confirmed cases of pneumonitis with new coronavirus infection, 12 severe cases, 3 critical cases, and no deaths. among them:

                      Among the confirmed cases, 5 were in Guangzhou, 15 in Shenzhen, 4 in Zhuhai, 1 in Foshan, 2 in Shaoguan, 1 in Huizhou, 1 in Zhongshan, 2 in Zhanjiang, and 1 in Zhaoqing. Among the severe cases, 8 were in Shenzhen, Zhuhai, One in Foshan, one in Shaoguan, and one in Huizhou. Among the critical cases, two were in Shenzhen and one in Zhuhai.

                      At present, 212 close contacts have been traced, all of them under medical observation.

                      Among the 32 confirmed cases in our province, 17 were males and 15 were females, aged between 10 and 81 years. Among them, 28 cases had a history of living or traveling in Hubei before onset, and 4 cases had no Hubei before onset. Residents' history or travel history, but they are all family members of imported cases in Hubei. A total of 6 cluster epidemics were found, all of which were clusters of families, involving 17 cases and no medical staff.

                    http://wsjkw.gd.gov.cn/zwyw_yqxx/con...t_2878571.html

                    Comment


                    • We already have both Hong Kong cases listed as positive. Here is an article sourced back to government media. The CHP website is not updated. Even their chart is not updated. Not sure what is going on.

                      Hong Kong Department of Health Centre for Health Protection: 2 cases tested positive for new coronavirus

                      January 23, 2020 11:14 Source: CCTV News Client


                        The Hong Kong Centre for Health Protection announced that a total of 135 suspected cases meeting the reporting criteria have been received so far, of which 97 have been ruled out of the new coronavirus infection and have been discharged from hospital.

                      The remaining 38 remain in hospital,

                      of which 2 have preliminary test results on the new coronavirus Positive. (Reporter Luo Wei)

                      http://www.ce.cn/xwzx/gnsz/gdxw/2020...34181513.shtml

                      Comment


                      • And...a new province...Jilin:

                        National Health and Health Commission confirms the first confirmed case of pneumonia in our province with imported new coronavirus infection

                        • Source: Jilin Provincial Health Committee
                        • Release time: 2020-01-23

                          On January 22, a suspected case returning home from Wuhan in Changchun was assessed and confirmed by the State Health and Health Commission as the first confirmed case of pneumonia imported from our country with a new coronavirus infection.

                          The patient was a 42-year-old female. She returned from Wuhan on January 19 due to fever and cough to a designated medical institution. The medical institution highly suspected that it was a suspected case and treated it in isolation. After reviewing the laboratory of the Chinese Center for Disease Control and Prevention, combined with the clinical manifestations and epidemiological history of the patient, the diagnostic expert group of the National Health and Health Commission evaluated and confirmed that it was a confirmed case of pneumonia with new coronavirus infection. At present, the patient's condition is stable. Medical observation has been carried out on those who have been in close contact with him, and no abnormalities such as fever have been found.

                          The Jilin Provincial Party Committee and Provincial Government attach great importance to the prevention and control of pneumonia outbreaks of new coronavirus infection, strengthen the leadership of epidemic prevention and control organizations, strictly implement territorial responsibilities and departmental responsibilities, and take strict work discipline. The health and health department has strengthened prevention and control throughout the entire process, all fields, and all hours. The province has set up provincial, city and county three-level medical treatment expert groups to determine 68 new-type coronavirus-infected pneumonia designated treatment medical institutions, and 131 medical institutions have launched fever clinics. , Refining and realizing early detection, early reporting, early isolation, early treatment and centralized cases, centralized experts, centralized resources, and centralized treatment measures, fully block input and prevent proliferation.

                          Experts suggest that winter and spring are the seasons when respiratory infectious diseases are high, and also the period when viral pneumonia is high. It is hoped that the general public will do a good job of personal hygiene protection, wear a mask when going out, maintain hand hygiene, and maintain indoor sanitation and air circulation. If you have fever or respiratory infection symptoms, please go to a local medical institution for a hot clinic in time.

                        http://wsjkw.jl.gov.cn/xwzx/xwfb/202...3_6598562.html

                        Comment


                        • Fujian reports 3 new cases of pneumonia with imported new coronavirus infection

                          Published: 2020-01-23 11:31:42 | Source: Xiamen Daily | Author: Anonymous
                          More News Enter News Center

                          At 11:00 on January 23, 2020, Fujian Province reported three new cases of pneumonia with imported new coronavirus infection. Among them: Xiamen City, Quanzhou City, and Ningde City each reported one confirmed case, all of which were the first confirmed cases.

                          The new patients are returnees from Wuhan. At present, the patients are in stable condition and are being treated in isolation. The close contacts tracked are undergoing medical observation.





                          http://news.china.com.cn/2020-01/23/...t_75643593.htm

                          Comment



                          • Three new cases of pneumonia confirmed by new coronavirus infection in Hunan Province

                            Source: New Hunan Client. Health Highlights
                            2020-01-22 17:50:48
                            Hunan Daily ? New Hunan Client January 22 (Reporter Duan Hanmin) On January 22, Hunan province added 3 new cases of pneumonia diagnosed with a new type of coronavirus infection. All patients were from Hecheng District, Huaihua City.

                            Patient Yang Moumou, female, 35 years old, Li Moumou, female, 40 years old, Peng Moumou, male, 30 years old, three of them were colleagues of the same company. Yang Moumou and Li Moumou visited Wuhan in late December, and Peng Moumou is a close contact with one of them. At present, three patients are in stable condition and are being treated in isolation at the designated hospital in Huaihua City. The local health and other departments have followed up and followed up the close contacts. The close contacts have no abnormalities such as fever.

                            The Hunan Provincial Party Committee and the Provincial Government attach great importance to the prevention and control of pneumonia outbreaks of new coronavirus infections, and organized all relevant departments, cities and states to cooperate in joint prevention and control. The health and health department strictly implements the system of pre-screening and triage of medical institutions, sending out hotspots, synchronizing the work of case isolation, epidemiological investigation, detection and diagnosis, and close contact follow-up management, and goes all out to fight the epidemic. To effectively protect the lives of the people.

                            Those who have recent residence, travel history, and close contact history in Wuhan. If they have fever, cough, or respiratory infections, they must go to the nearest designated medical institution.


                            https://m.voc.com.cn/wxhn/article/20...appinstalled=0

                            Comment


                            • New confirmed pneumonia case of imported new coronavirus infection in Liaoning

                              2020-01-23 11:56:26  China News Network
                                China News Service, January 23, according to the official Weibo news of the Liaoning Provincial Health and Health Commission, on January 23, 2020, Liaoning added one new confirmed case of pneumonia imported with new coronavirus infection.



                                Screenshot of Liaoning Provincial Health and Health Commission Weibo

                                The female patient, 50 years old, worked on the Shenyang-Wuhan high-speed rail and returned to Shenyang from Wuhan with the high-speed rail on January 15. He was treated at a clinic in Shenyang for symptoms of pharynx on January 16; he was admitted to a certain hospital in Shenyang on January 22 and was admitted to hospital for isolation and treatment. At present, the patient's symptoms are stable, and 37 of his close contacts are under medical observation.

                                As of 11:00 on January 23, Liaoning Province had reported 3 confirmed cases of pneumonia due to new coronavirus infection. At present, all three patients are treated in isolation at designated hospitals, and their condition is stable. All close contacts were medically observed.

                              http://news.workercn.cn/32843/202001...15628638.shtml

                              Comment


                              • Hubei government announcement -


                                444 cases of pneumonia diagnosed with new coronavirus infection in the province



                                2020-01-23 10:01  |  Hubei Daily


                                On January 22, our province held a press conference on the prevention and control of pneumonia outbreaks of new coronavirus infections. As of 20:00 on January 22, Hubei Province has reported a total of 444 cases of pneumonitis infected by new-type coronavirus (from 00:00 to 20:00 on January 22, 69 new cases of pneumonitis infected by new-type coronavirus were newly added in Hubei Province, of which new (62 cases increased, 8 cases died; 6 cases increased in Jingzhou City, 1 case increased in Jingmen City), 28 cases have been cured and 17 patients have been discharged. At present, 399 patients are still being treated in the hospital, of which 71 cases are critically ill and 24 cases are critically ill. They are all under isolation treatment at designated medical institutions. A total of 2,556 close contacts have been tracked, 863 people have been released from medical observation, and 1693 people are still receiving medical observation.

                                Yang Yunyan, deputy governor and deputy commander of the provincial pneumonia prevention and control command of the new type of coronavirus infection, attended the press conference and introduced the province's prevention and control work.

                                Since January 2, the Provincial Party Committee and the Provincial Government have held a number of special meetings to analyze and determine the situation of the epidemic situation, and study the disposal of the epidemic situation. The provincial government has set up a leading group and a special working class to coordinate and dispatch the epidemic prevention and control work, to discuss daily and report daily to study and solve major problems. The Provincial Health and Health Committee and Wuhan Municipal Government established the frontline command for epidemic situation disposal, established a joint epidemic handling mechanism, and dealt with various specific problems in a timely manner. Save patients' lives first, focus on the best medical resources in the province, and organize medical treatment. From January 12, all confirmed cases in the hospital will be transferred to Wuhan Jinyintan Hospital for centralized treatment. Establish a provincial and municipal joint medical expert group to draw authoritative experts from Tongji Hospital, Xiehe Hospital, Provincial People's Hospital, and Zhongnan Hospital to take a responsible and responsible approach to strengthen the treatment of critically ill patients.

                                Under the guidance of the National Health Commission, it actively organized and implemented epidemiological investigations, specimen collection and inspection, source tracing, monitoring and analysis, and timely grasped the research and judgment and evaluation of virus mutations.

                                From January 14th, the temperature of passengers departing from Han will be tested at the airports, stations and terminals in Wuhan. "Daily disinfection" and "Ventilation per shift" of public transportation in the city. The South China Seafood Market will be closed for remediation from January 1st, and a centralized and specialized remediation of the Wuhan agricultural (market) market and various business establishments will be carried out to eliminate the relevant markets and the living environment of hospitals, patients and close contacts. Cumulative disinfection area is 304010 square meters. Wuhan launched a patriotic sanitary campaign in winter and spring with the theme of "renovating the environment, cleaning homes, and welcoming the festival". It cleared 309 tons of garbage, used 48,550 rodent control facilities, and put 860 kg of rat medicine.

                                In addition, our province also strengthened information disclosure and public opinion guidance. The situation report and authoritative interpretation were published on the official website of Wuhan Municipal Health and Health Commission, and the epidemic situation information was released on a regular basis. The mainstream media, new media, and self-media are used to continuously publish health science popularization knowledge and improve the people's awareness of self-protection.

                                At present, the situation of epidemic prevention and control in our province is still very grim. The number of confirmed cases in Wuhan has increased rapidly, and confirmed cases have been reported in many places inside and outside the province. The virulence of the virus still needs to be continuously observed and evaluated, and the infectivity is still uncertain. In addition, the Spring Festival is approaching and the dense movement of personnel does not rule out the possibility of a continuous increase in the number of cases and outbreaks. The situation is changing rapidly, which brings great challenges to prevention and control.

                                According to the decision-making and deployment of the Party Central Committee and the State Council, our province has comprehensively strengthened the ideas, strategies and measures for the next step of epidemic prevention and control: the establishment of the provincial pneumococcal infection prevention of new coronavirus infection by the provincial party committee and the chief person in charge of the provincial government. Control headquarters, set up special classes to comprehensively coordinate the prevention and control of the epidemic situation; initiate the second-level response to public health emergencies in the province, and establish prevention and control leadership agencies in various places to mobilize all-out; in accordance with "law, regulations, territorial management, The principles of improving the mechanism, responding reasonably, relying on science, being powerful and effective, being open and transparent, and seeking truth from facts, and implementing internal non-proliferation and external prevention export measures. (Hu Man Longhua)


                                http://wjw.hubei.gov.cn/fbjd/dtyw/20..._2014421.shtml

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