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    January 12, 2020 10:12

    "Father of Coronavirus" Lai Mingzhang: Wuhan pneumonia may still be transmitted from person to person due to viral gene mutation

    Source / Health Magazine
    By Qiu Shuyi pix / pixabay

    The unknown pathogen of Wuhan unknown pneumonia was initially identified as a new type of coronavirus, and it is presumed that it was transmitted from animals to humans. Academician of the Chinese Academy of Sciences and "Father of Coronavirus" Lai Mingxuan said that coronaviruses are prone to genetic mutations, and epidemic prevention agencies and the general public must not be taken lightly.
    ...
    Dr. Lai Mingkun, a top international researcher on coronaviruses, said that SARS (Severe Acute Respiratory Syndrome) in 2003 and MERS (Middle East Respiratory Syndrome Coronavirus Infection) in 2012 were both coronaviruses that were transmitted from animals to humans and the virus was genetically mutated to become Respiratory diseases with high infectiousness and high mortality rate, therefore, the new coronavirus of Wuhan pneumonia should be waited for in epidemic prevention.

    Beware of mutations of new viruses that directly infect humans

    Lai Minghuan said that coronavirus is a type of RNA virus, and "genes are susceptible to mutation" is a feature of RNA viruses. Many animals in nature carry coronaviruses, especially bats. Bats are the largest hosts of coronaviruses. Coronaviruses on bats do not directly infect humans, but mutations in the virus genes become new viruses that infect other animals and may be transmitted to humans.

    For example, SARS in 2003 infected the civet with a bat coronavirus mutation and was finally passed on to humans. Another example is the Middle Eastern coronavirus that appeared in Saudi Arabia in 2012 and is also a mutation of a bat coronavirus. Camels were transmitted to tourists. The resulting MERS later caused a pandemic in South Korea, with a mortality rate of 30%, which is higher than SARS.
    ...
    Lai Mingchen said that both SARS and MERS are new coronaviruses with mutations in bat coronavirus. It is unclear which animal the new coronavirus from Wuhan pneumonia came from this time, and he speculated that it is also likely that the coronavirus mutation in bats infected them. Wild animals are transmitted to humans.

    Eliminate virus transmission channels without touching wildlife

    He said that the coronavirus in animals, after genetic mutations are transmitted to humans, is likely to continue to mutate in humans and become human-to-human coronaviruses. At present, there is no obvious evidence of human-to-human transmission in Wuhan pneumonia, but the absence of evidence does not mean that it will not If it happens, the possibility of gene mutation cannot be completely ruled out. Now people who have been to Wuhan and have been exposed to wild animals become carriers without knowing it. Once the virus mutates into a virus that directly infects humans, a large-scale epidemic may break out.

    He said that the best prevention strategy is of course to block at the stage of "animals transmit the virus to humans" to avoid the possibility of new viruses becoming SARS or the Middle East coronavirus. He said that the coronavirus transmission channels include animal droplets, urine and feces. He urged the public to avoid going to traditional markets to contact live wild animals, especially those who went to Wuhan in mainland China to be cautious. If there are fever symptoms after returning to Taiwan, it is recommended to isolate and observe , Do a good job of self-health management.

    ...
    https://health.ettoday.net/news/1623700
    "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
    -Nelson Mandela

    Comment


    • China to share new coronavirus gene sequence information with World Health Organization

      The National Health Committee of China released news on the evening of the 11th that the unexplained viral pneumonia epidemic in Wuhan has attracted wide attention from all walks of life. In order to maintain global health security, China will share the undetected viral pneumonia cases detected in Wuhan with the World Health Organization. Novel Coronavirus Gene Sequence Information.

      Recently, unexplained viral pneumonia in Wuhan, which has attracted widespread attention, has been initially determined to be caused by a new type of coronavirus. A preliminary assessment of the results of pathogen detection by the expert group revealed recently that as of 21:00 on January 7, 2020, a new coronavirus was detected in the laboratory, the whole genome sequence of the virus was obtained, and positive results of the new coronavirus were detected by nucleic acid detection methods. In 15 cases, the virus was isolated from a sample of a positive patient and showed typical coronavirus appearance under an electron microscope.

      Wang Guangfa, an expert of the National Medical Experts Group and the chief physician of the Department of Respiratory and Critical Care Medicine of the First Hospital of Peking University, told the media recently that the identification of the pathogen is a milestone in the prevention and treatment of the disease. The pathogen was initially identified and can not only be used for clinical screening. It is important to design a PCR test kit, which is very important for the follow-up treatment plan and epidemic prevention and control.

      Wang Guangfa pointed out that at present, the patient's condition and overall epidemic situation are under control. But the expert group's understanding of the virus is still in the exploration stage, and whether there will be new changes in the future still needs further observation and research.

      In response to the cause of the disease that the public is more concerned about, Wang Guangfa said that in general, it may take a long time for scientific research to trace the source of a disease. The public should uphold the scientific attitude and have a reasonable expectation for this.

      The Wuhan Municipal Health and Health Commission reported on the 11th that 41 cases of pneumonia with a new coronavirus infection were initially diagnosed, of which 2 were discharged, 7 were severe, and 1 died. The remaining patients were in stable condition since January 3, 2020 No new cases were found. (Reporter Li Yanan)

      http://www.fj.chinanews.com/news/fj_...12/458195.html

      Comment


      • WHO: China has published a new coronavirus gene map, which can be viewed by countries




        The outbreak of unexplained pneumonia in Wuhan involves a new type of coronavirus, but the authorities have not released the genetic information of the new virus. Some scholars from Shanghai Fudan University uploaded the genes of the new virus to the medical website yesterday (11th). It was announced this morning (12th) Hong Kong time that the complete genetic sequence shared by China had been received. It was also revealed that the authorities had officially uploaded relevant information to a public data platform for researchers and public health departments of various countries to view.

        Some local experts pointed out that the complete information will help laboratory staff to design more accurate rapid tests, and it is estimated that the new tests can be applied within a few days, and the mainland has the corresponding technology. Therefore, 59 confirmed cases were announced earlier. Screened to the latest 41 cases.







        社會新聞





        撰文:陳倩婷



        2020-01-12 14:43
        最後更新日期:2020-01-12 14:43 武漢的爆發的不明原因肺炎涉一種新型冠狀病毒,惟當局一直未公布新病毒的基因資料,有上海復旦大學的學者昨 日(11日)將新型病毒的基因先行上載至醫學網站,世界衞生組織至香港時間今晨(12日)公布,已收到中國 分享的完整基因序列,又透露當局已正式將相關資料上載至一個公開的數據平台,讓研究員及各國公共衞生部門可 以閱覽。
        有本地專家指,完整的資料有助實驗室人員設計出更準確的快速測試,又估計新測試數日內可應用,而且內地已有 相應技術,因此確診的病例由較早前公布的59宗,篩檢至最新的41宗個案。





        WHO Director-General Tedros Adhanom said that he had contacted Ma Xiaowei, the director of the National Health and Health Committee, and praised him for sharing the information about the new coronavirus with the Chinese government with the world.




        New quick test available within a few days

        Kong Fanyi, assistant dean of the University of Hong Kong School of Medicine and director of the Department of Infectious Diseases of the Department of Internal Medicine, said that all the genes of the virus have been obtained. It is expected that a new rapid PCR test can be designed within a few days to a week to test whether the patient sample is correct for Wuhan. The new virus is positive, and he expects the new test to take three to four hours to produce results.

        Professor Xu Shuchang, Chair Professor of Respiratory Medicine, The Chinese University of Hong Kong School of Medicine said that 59 cases have been diagnosed with the new coronavirus infection since the Mainland already has the corresponding testing technology, and cases were screened out after testing until January. A total of 41 cases were confirmed on the 11th.

        Mainland scholars upload virus genes to medical websites

        Since the outbreak of unexplained pneumonia, the mainland authorities have only disclosed news about the local epidemic through the mainland media. No information on the new coronavirus has been made public. Hong Kong experts also raised this at a press conference earlier, hoping that the authorities will share the genetic sequencing as soon as possible. To speed up the identification of confirmed patients.

        Until yesterday, mainland scholars exposed the data first, so that the outside world could learn more information, including the new virus genus Coronavirus 2B typing, whose gene sequence is 73% the same as that of SARS virus.

        https://www.hk01.com/%E7%A4%BE%E6%9C...96%B1%E8%A6%BD

        Comment


        • SARG reps to visit Wuhan

          January 11, 2020

          Under Secretary for Food & Health Dr Chui Tak-yi will visit Wuhan on January 13 to examine the situation concerning the cluster of pneumonia cases, the Food & Health Bureau announced today.

          The bureau said with the arrangement of the National Health Commission, Dr Chui will go to Wuhan, together with representatives from the Department of Health and Hospital Authority, to learn about the prevention and control measures and clinical management there.

          They will return to Hong Kong on January 14.




          https://www.news.gov.hk/eng/2020/01/...ml?type=ticker

          Comment


          • Wuhan notification of new coronavirus infection pneumonia: 717 people still under observation

            People's Daily Online, Beijing, January 12th According to the website of the Wuhan Municipal Health and Health Committee, there were no new cases of pneumonia caused by new coronavirus infection in Wuhan from 04:00 to 14:00 on January 11, 2020, and 4 cases were discharged without additional deaths. Case Reports.

            As of now, Wuhan has reported 41 cases of pneumonitis with new coronavirus infection, 6 of whom have been discharged from hospital, 7 of them are in critical condition, and 1 of them has died. The remaining patients are in stable condition. All patients received isolation treatment at designated medical institutions in Wuhan. A total of 763 close contacts have been tracked, 46 medical observations have been lifted, and 717 people are still receiving medical observations. Among the close contacts, no related cases were found.

            http://js.people.com.cn/n2/2020/0112...-33709985.html

            Comment


            • Originally posted by tetano View Post
              Wuhan notification of new coronavirus infection pneumonia: 717 people still under observation

              People's Daily Online, Beijing, January 12th According to the website of the Wuhan Municipal Health and Health Committee, there were no new cases of pneumonia caused by new coronavirus infection in Wuhan from 04:00 to 14:00 on January 11, 2020, and 4 cases were discharged without additional deaths. Case Reports.

              As of now, Wuhan has reported 41 cases of pneumonitis with new coronavirus infection, 6 of whom have been discharged from hospital, 7 of them are in critical condition, and 1 of them has died. The remaining patients are in stable condition. All patients received isolation treatment at designated medical institutions in Wuhan. A total of 763 close contacts have been tracked, 46 medical observations have been lifted, and 717 people are still receiving medical observations. Among the close contacts, no related cases were found.

              http://js.people.com.cn/n2/2020/0112...-33709985.html
              Gov report:

              Wuhan Municipal Health and Health Committee's report on pneumonia of new coronavirus infection

              Issuing authority: Wuhan City health committee | Published: 2020-01-12 20:10:13

              At 04:00 on January 11, 2020, there were no new cases of pneumonia infected with new coronavirus in our city, 4 cases were cured and discharged, and no new deaths were reported.

              Up to now, the city has reported a total of 41 cases of pneumonia caused by new coronavirus infection , 6 cases have been cured and discharged, 7 cases are being treated in severe cases, and 1 case has died . A total of 763 close contacts have been tracked , 46 medical observations have been lifted, and 717 people are still receiving medical observations. Among the close contacts, no related cases were found.



              January 12, 2020


              http://wjw.wuhan.gov.cn/front/web/sh.../2020011209037

              Comment


              • GISAID, The Chinese Center for Disease Control and Prevention, Chinese Academy of Science, Chinese Academy of Medical Science, EpiFlu Database Courtesy: IVDC, China CDC

                China releases genetic sequence of newly discovered coronavirus from Wuhan


                The Chinese Center for Disease Control and Prevention, the Chinese Academy of Science and the Chinese Academy of Medical Science released through the GISAID Initiative the genome sequence of a newly discovered coronavirus. The virus was identified during an outbreak in the city of Wuhan, where patients were suffering from respiratory illnesses such as pneumonia since late December 2019.

                The genome sequence of this betacoronavirus is crucial to develop specific diagnostic tests and to identify potential intervention options

                https://www.gisaid.org/

                Comment


                • Novel Coronavirus – China


                  Disease outbreak news : Update
                  12 January 2020


                  On 11 and 12 January 2020, WHO received further detailed information from the National Health Commission about the outbreak.

                  WHO is reassured of the quality of the ongoing investigations and the response measures implemented in Wuhan, and the commitment to share information regularly.

                  The evidence is highly suggestive that the outbreak is associated with exposures in one seafood market in Wuhan. The market was closed on 1 January 2020. At this stage, there is no infection among healthcare workers, and no clear evidence of human to human transmission. The Chinese authorities continue their work of intensive surveillance and follow up measures, as well as further epidemiological investigations.

                  Among the 41 confirmed cases, there has been one death. This death occurred in a patient with serious underlying medical conditions.

                  China shared the genetic sequence of the novel coronavirus on 12 January, which will be of great importance for other countries to use in developing specific diagnostic kits.

                  The cluster was initially reported on 31 December 2019, when the WHO China Country Office was informed. The Chinese authorities identified a new type of coronavirus (novel coronavirus, nCoV), which was isolated on 7 January 2020. Laboratory testing was conducted on all suspected cases identified through active case finding and retrospective review. Other respiratory pathogens such as influenza, avian influenza, adenovirus, Severe Acute Respiratory Syndrome coronavirus (SARS-CoV), Middle East Respiratory Syndrome coronavirus (MERS-CoV) were ruled out as the cause.

                  According to information conveyed to WHO by Chinese authorities on 11 and 12 January, 41 cases with novel coronavirus infection have been preliminarily diagnosed in Wuhan City. Of the 41 cases reported, seven are severely ill. This is when the one death, mentioned above, was reported, in a patient with other underlying health conditions. Six patients have been discharged from hospital. Symptom onset of the 41 confirmed nCoV cases ranges from 8 December 2019 to 2 January 2020. No additional cases have been detected since 3 January 2020.

                  The clinical signs and symptoms reported are mainly fever, with a few cases having difficulty in breathing, and chest radiographs showing invasive pneumonic infiltrates in both lungs. National authorities report that patients have been isolated and are receiving treatment in Wuhan medical institutions.

                  According to the preliminary epidemiological investigation, most cases worked at or were handlers and frequent visitors to the Huanan Seafood Wholesale Market. The government reports that there is no clear evidence that the virus passes easily from person to person.

                  Currently, no case with infection of this novel coronavirus has been reported elsewhere other than Wuhan. Public Health Response


                  China's National Health Commission has deployed a group of experts to Wuhan City to support the local response.

                  National authorities have reported the following response measures:
                  • A total of 763 close contacts including healthcare workers, have been identified and followed up and no additional cases of infection with the novel coronavirus have been identified;
                  • The Wuhan Municipal Health Commission carried out active case finding, and retrospective investigations of the current cluster of patients have been completed
                  • The Huanan Seafood Wholesale Market has been temporarily closed to carry out environmental sanitation and disinfection;
                  • Public risk communication activities have been carried out to improve public awareness and adoption of self-protection measures.

                  WHO is closely monitoring the situation and is in regular contact with national authorities in China to provide support required. Technical guidance on novel coronavirus has been developed and will continue to be updated as additional information is available. WHO risk assessment


                  To date, investigations are still under way to assess the full extent of the outbreak.

                  Wuhan city is a major domestic and international transport hub. To date, there have been no reported cases outside of Wuhan City.

                  More comprehensive information and ongoing investigations are also required to better understand the epidemiology, clinical picture, source, modes of transmission, and extent of infection; as well as the countermeasures implemented. WHO advice


                  Based on information provided by national authorities, WHO’s recommendations on public health measures and surveillance for novel coronaviruses apply.

                  WHO does not recommend any specific health measures for travellers. In case of symptoms suggestive of respiratory illness either during or after travel, travellers are encouraged to seek medical attention and share travel history with their healthcare provider. Travel guidance has been updated.

                  WHO advises against the application of any travel or trade restrictions on China based on the information currently available on this event.

                  For more information:https://www.who.int/csr/don/12-janua...irus-china/en/
                  "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
                  -Nelson Mandela

                  Comment


                  • 2nd suspected case of Wuhan virus in Singapore tests negative

                    The second person who was placed in isolation here in case he had contracted the Wuhan virus has been cleared, said the Ministry of Health (MOH) last Saturday.

                    Epidemiological investigations, clinical assessment and laboratory test results from the suspect case reported on Friday found that it was not linked to the pneumonia cluster in Wuhan, said the ministry.



                    The man, 26, was a Chinese national with pneumonia and a travel history to Wuhan.


                    Read more: https://newsinfo.inquirer.net/121245...#ixzz6Atqo6ivx
                    Follow us: @inquirerdotnet on Twitter | inquirerdotnet on Facebook



                    Comment





                    • Taiwan adds 1 new case of suspected coronavirus! 40 year old woman with high fever isolated

                      A new case of suspected 2019 coronavirus was added in China today. Luo Yijun said that the 40-year-old southern woman went to Wuhan to visit relatives in early January, but did not have a history of travel to the South China seafood market or contact with animals. The woman returned to China from 1/8 and began to have fever on 1/12. She has eliminated the possibility of flu through quick screening.

                      'Although this suspected patient has a fever, there is no pneumonia. Now he is being admitted to a negative pressure isolation ward, but the chances of a new type of coronavirus in 2019 are really low.' Luo Yijun pointed out.

                      https://today.line.me/tw/pc/article/...4%B8%AD-PokGJo

                      Comment


                      • Coronavirus-infected Chinese tourist being treated in Thailand

                        A Chinese tourist was found to be infected with the new strain of coronavirus when she arrived in Thailand, is being treated in hospital and is expected to be discharged in a few days, Public Health Minister Anutin Charnvirakul said on Monday.

                        Mr Anutin said the 61-year-old woman was recovering at Bamrasnaradura Infectious Diseases Institute in Nonthaburi province.

                        She now had no fever or any respiratory symptoms. If doctors gave her a clearance she would be allowed to go home in a few days, said Mr Anutin.




                        Sixteen other people who were close to the woman on the same flight were examined, and the results were negative, he said.


                        https://www.bangkokpost.com/thailand...ed-in-thailand

                        Comment


                        • Source: https://www.bloomberg.com/news/artic...ke-virus-found

                          New SARS-Like Virus Found in Traveler From China, Thailand Says
                          By Jason Gale
                          and Randy Thanthong-Knight
                          January 12, 2020, 11:52 PM EST Updated on January 13, 2020, 4:13 AM EST

                          Patient admitted to hospital in Bangkok has since recovered
                          China identified 41 cases, down from 59 previously counted

                          A traveler from China who arrived in Bangkok was infected with the newly identified virus believed to have triggered a pneumonia outbreak in central China, Thai officials said.

                          The patient, who was hospitalized on Jan. 8 at the Bamrasnaradura Infectious Diseases Institute, tested positive for the novel coronavirus linked to the outbreak in Wuhan, in Hubei province, the Thai Ministry of Public Health said in a statement Monday. The patient has since recovered and is well enough to be repatriated.

                          It’s the first reported case of someone outside China being infected with the novel virus, which has captured international attention because of similarities with the one that sparked Severe Acute Respiratory Syndrome, or SARS, 17 years ago. Unlike SARS, which killed almost 800 people, the new virus doesn’t appear to spread easily between people.

                          “I’d like to ask the public not to be alarmed,” Anutin Charnvirakul, Thailand’s deputy premier and health minister, said in the statement. “The detection of the patient shows that we have an efficient system of surveillance. We’re confident that we can control the situation.”...

                          Comment


                          • Source: https://www.miragenews.com/who-state...s-in-thailand/

                            January 13, 2020 10:56 pm AEDT
                            WHO statement on novel coronavirus in Thailand

                            The World Health Organization (WHO) is working with officials in Thailand and China following reports of confirmation of the novel coronavirus in a person in Thailand.

                            The person was a traveler from Wuhan, China, and was identified by Thai officials on 8 January, and hospitalized that day. The person is recovering from the illness according to Thai officials.

                            The possibility of cases being identified in other countries was not unexpected, and reinforces why WHO calls for on-going active monitoring and preparedness in other countries. WHO has issued guidance on how to detect and treat persons ill with the new virus...

                            Comment


                            • Government report:

                              The Ministry of Health has emphasized that there is currently no outbreak. Surveillance measures Prevention and control of Thai disease. Found early, early treatment


                              Ministry of Public Health Reiterated that there is currently no outbreak of a new strain of the corona virus. Thailand has the potential for both surveillance measures. Prevent disease control Screening and screening patients quicker Get early treatment Revealed that a patient confirmed the infection of a new species of coronary virus traveling from Wuhan, the first one detected outside China. At this time, no fever. And ready to return to the country

                              Today (13 January 2020) at the Ministry of Public Health, Nonthaburi Province, Mr. Anutin Charnwirakul, Deputy Prime Minister and Minister of Public Health Along with Dr. Satit Patu-Techa, Deputy Minister of Public Health Dr. Sukhum Kanchanaphimai, Permanent Secretary, Ministry of Public Health Dr. Suwanchai (MD) Wattana Yingcharoenchai Director-General of the Department of Disease Control Doctor Opas Karwarin Pong Director-General of the Department of Medical Sciences And Dr. Daniel Kurtace, Representative of the World Health Organization in Thailand Press release on surveillance measures Prevention and control of a new strain of corona virus.

                              Mr Anutin said that Thailand has implemented surveillance measures for screening patients traveling from Wuhan city since January 3, 2016. 2020 at Suvarnabhumi International Airport, Don Mueang, Phuket and Chiang Mai, as well as surveillance at public and private hospitals. All 12 criteria have been met, with most being infected with seasonal influenza. 8 patients were treated with a high fever, detected by a thermo-scan at Suvarnabhumi Airport. Admitted to the negative pressure disease separation room Bamrasnaradura Institute on January 8, 2020. The results of laboratory tests on January 12, 2020 found a new strain of the corona virus. Which is the first in Thailand and the first detected outside of China Currently healed And ready to return to the country At this time, no new strains of the corona virus infection have been found in Thailand. And there is a surveillance for all medical personnel who provide care Found that no one was infected with this

                              "The Prime Minister has already learned You have given the policy of asking people to provide true information. The government is ready to support information and encourage public health care providers to look after this situation. Asking the public to not panic Finding patients is an effective means of our surveillance system. Confident that we can control the situation very well, "said Anutin

                              Mr Anutin added that The Ministry of Public Health has the potential and readiness in public health. There is an international standard for diagnosis and medical care. There is close coordination with the World Health Organization. International agency for infectious diseases All related agencies such as the Ministry of Transport Ministry of Foreign Affairs Ministry of Tourism and Sports National Police Agency And departments within the airport Join hands to build trust among citizens and tourists Raise surveillance measures and prevent the spread of disease By screening plane passengers on the direct route from Wuhan city to all 4 international airports, surveillance in both public and private hospitals. Including communities in tourist areas People can continue to travel as usual. If traveling back from the outbreak area of ​​Wuhan within 14 days and have fever, sore throat, mucus, cough, sputum or wheezing Ask to see a doctor immediately Or notify the Ministry of Public Health Department of Disease Control Hotline

                              ********************************* 13 January 2020


                              https://pr.moph.go.th/?url=pr/detail/2/04/136970/

                              Comment


                              • Source: https://www.weibo.com/5476386628/Ipk...d1578918555518

                                Today 19:16
                                [# 武汉 无 added new coronavirus infection pneumonia cases #] Today, the Wuhan Health and Medical Commission reported that there were no new pneumonitis cases infected with new coronavirus infection in Wuhan, and one case was cured and no new deaths were reported.

                                Up to now, Wuhan has reported 41 cases of pneumonitis with new coronavirus infection, 7 cases have been cured and discharged, 6 cases are being treated in severe cases, and 1 case has died. A total of 763 close contacts have been tracked, 76 medical observations have been lifted, and 687 are still receiving medical observations. Among the close contacts, no related cases were found. (CCTV)



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