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The Brazilian study, published in the Journal of the American Medical Association Network Open (Jama), was halted by a safety monitoring board before even one-quarter of the planned 440 patients were enrolled. Eighty-one patients with Covid-19 or suspected Covid-19 were given a daily regimen of chloroquine. The randomized clinical trial separated the patients into a high-dose and a low-dose group.
Researchers planned to assess their outcomes after 28 days.
But after 13 days, six of 40 patients in the low-dose group had died, compared with 16 of 41 patients in the high-dose group. Furthermore, five patients in the high-dose group had underlying heart disease, three of whom died.
https://www.theguardian.com/world/20...navirus-brazil
Researchers planned to assess their outcomes after 28 days.
But after 13 days, six of 40 patients in the low-dose group had died, compared with 16 of 41 patients in the high-dose group. Furthermore, five patients in the high-dose group had underlying heart disease, three of whom died.
https://www.theguardian.com/world/20...navirus-brazil