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Open Forum Infect Dis
. 2023 Dec 18;11(1):ofad635.
doi: 10.1093/ofid/ofad635. eCollection 2024 Jan. Three Years of the Coronavirus Disease 2019 Pandemic in a European Region: A Population-Based Longitudinal Assessment in Madrid Between 2020 and 2022
Juan Berenguer 1 2 3 , María J Calvo-Alcántara 4 , Alejandro Alvaro-Meca 3 5 , José C Estévez 6 , Miguel Basanta 7 , Sergio Ruiz 6 , Ángel L Matáix 4 , César Bienzóbas 8 , Lourdes Cosano 1 , Aura P Silva 1 , Pilar Salas 1 , Pedro Gullón 9 , Manuel Franco 9 , José R Arribas 3 10 11 12 , José M Molero 13 , Miguel A Hernán 14
Affiliations
Background: Our objective was to assess the health impact of coronavirus disease 2019 (COVID-19) during 2020-2022 in the Madrid region.
Methods: We included all individuals registered in the Madrid Health System Registry as of 31 December 2019, and followed them until 31 December 2022. Using a unique personal identifier, we linked the databases of primary care, hospitals, pharmacies, certified laboratories performing diagnostic tests, vaccines, and mortality.
Results: Of 6 833 423 individuals, 21.4% had a confirmed COVID-19 diagnosis, and 1.5% had a COVID-19 hospitalization (primary diagnosis). Thirty-day mortality was 1.6% for confirmed COVID-19 (from 11.4% in first semester 2020 to 0.4% in first semester 2022). Thirty-day mortality was 10.8% for COVID-19 hospitalizations (from 14.0% in first semester 2020 to 6.0% in second semester 2022). There were 24 073 deaths within 30 days of a confirmed COVID-19 diagnosis. Advanced age, male sex, higher socioeconomic deprivation, and comorbidities were associated with higher mortality.
Conclusions: By linking administrative and clinical databases, we characterized the burden of the COVID-19 pandemic in Madrid over 3 years. Our analysis proposes a high-level framework for comparisons of the burden of COVID-19 across areas worldwide.
Keywords: COVID-19; SARS-CoV-2; coronavirus; population-based study.
. 2023 Dec 18;11(1):ofad635.
doi: 10.1093/ofid/ofad635. eCollection 2024 Jan. Three Years of the Coronavirus Disease 2019 Pandemic in a European Region: A Population-Based Longitudinal Assessment in Madrid Between 2020 and 2022
Juan Berenguer 1 2 3 , María J Calvo-Alcántara 4 , Alejandro Alvaro-Meca 3 5 , José C Estévez 6 , Miguel Basanta 7 , Sergio Ruiz 6 , Ángel L Matáix 4 , César Bienzóbas 8 , Lourdes Cosano 1 , Aura P Silva 1 , Pilar Salas 1 , Pedro Gullón 9 , Manuel Franco 9 , José R Arribas 3 10 11 12 , José M Molero 13 , Miguel A Hernán 14
Affiliations
- PMID: 38173846
- PMCID: PMC10763997
- DOI: 10.1093/ofid/ofad635
Background: Our objective was to assess the health impact of coronavirus disease 2019 (COVID-19) during 2020-2022 in the Madrid region.
Methods: We included all individuals registered in the Madrid Health System Registry as of 31 December 2019, and followed them until 31 December 2022. Using a unique personal identifier, we linked the databases of primary care, hospitals, pharmacies, certified laboratories performing diagnostic tests, vaccines, and mortality.
Results: Of 6 833 423 individuals, 21.4% had a confirmed COVID-19 diagnosis, and 1.5% had a COVID-19 hospitalization (primary diagnosis). Thirty-day mortality was 1.6% for confirmed COVID-19 (from 11.4% in first semester 2020 to 0.4% in first semester 2022). Thirty-day mortality was 10.8% for COVID-19 hospitalizations (from 14.0% in first semester 2020 to 6.0% in second semester 2022). There were 24 073 deaths within 30 days of a confirmed COVID-19 diagnosis. Advanced age, male sex, higher socioeconomic deprivation, and comorbidities were associated with higher mortality.
Conclusions: By linking administrative and clinical databases, we characterized the burden of the COVID-19 pandemic in Madrid over 3 years. Our analysis proposes a high-level framework for comparisons of the burden of COVID-19 across areas worldwide.
Keywords: COVID-19; SARS-CoV-2; coronavirus; population-based study.