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Western Pac Surveill Response J
. 2022 Sep 19;13(3):1-5.
doi: 10.5365/wpsar.2022.13.3.955. eCollection 2022 Jul-Sep.
Occurrence of the Omicron variant of SARS-CoV-2 in northern Viet Nam in early 2022
Trang Thi Hong Ung 1 , Phuong Vu Mai Hoang 1 , Son Vu Nguyen 1 , Hang Le Khanh Nguyen 1 , Phuong Thi Kim Nguyen 2 , Dan Tan Phan 3 , Thanh Thi Le 1 , Anh Phuong Nguyen 1 ; Thach Co Nguyen,a; Futoshi Hasebe 4 5 , Mai Thi Quynh Le 1
Affiliations
- PMID: 36688184
- PMCID: PMC9831598
- DOI: 10.5365/wpsar.2022.13.3.955
Abstract
The Omicron variant caused a surge of infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Viet Nam in early 2022, signalling community transmission. We report on active whole-genome sequencing surveillance of positive SARS-CoV-2 samples collected at that time in northern Viet Nam from international arrivals and community clusters. We used an amplicon protocol developed with 14 polymerase chain reaction products and the Illumina iSeq 100 platform. Overall, 213 nasopharyngeal or throat swabs were analysed, of which 172 samples were identified with the Omicron variant. Of these, 80 samples were collected from community cases in February 2022, among which 59 samples were sublineage BA.2 and one sample was the recombinant XE variant. Our results indicated that Omicron had replaced Delta as the dominant variant in a very short period of time and that continuously conducting active whole-genome sequencing surveillance is necessary in monitoring the evolution and genomic diversity of SARS-CoV-2 in Viet Nam.