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JAMA Netw Open: Outcomes and Mortality Among Adults Hospitalized With COVID-19 at US Medical Centers

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  • JAMA Netw Open: Outcomes and Mortality Among Adults Hospitalized With COVID-19 at US Medical Centers


    March 5, 2021

    Outcomes and Mortality Among Adults Hospitalized With COVID-19 at US Medical Centers


    Ninh T. Nguyen, MD1; Justine Chinn, BS1; Jeffry Nahmias, MD, MHPE1; et al


    Results

    Among 192 550 adults hospitalized with COVID-19 who were discharged from 555 US medical centers, 101 089 (52.5%) were men, 83 567 (43.3%) were White, and 125 543 (65.2%) had Medicare or Medicaid insurance. The most common comorbidities included hypertension (118 418 [61.5%]), diabetes (73 939 [38.4%]), and obesity (52 759 [27.4%]).

    Of patients in this cohort, 55 593 (28.9%) were admitted to the ICU, 26 221 (13.6%) died during the index hospitalization, and 5839 (3.0%) were transferred to hospice care (Table). In-hospital mortality increased in association with increasing age; 179 of 12 644 patients (1.4%) aged 18 to 29 years died, and 8277 of 31 135 patients (26.6%) 80 years or older died. Of the patients admitted to the ICU, 15 431 of 55 593 (27.8%) died (Figure, A). The median hospital length of stay among patients who were not admitted to the ICU was 6 days (interquartile range [IQR], 3-8 days), with a median cost per admission of $10 520 (IQR, $8031-$14 550). The median hospital length of stay for those admitted to the ICU was 15 days (IQR, 6-20 days), with a median cost per admission of $39 825 (IQR, $25 763-$56 804). There was a significant reduction in mortality over the course of the 6-month period, with the highest mortality in March (3657 of 16 517 patients died [22.1%]); mortality decreased each month until the end of the study period in August (1154 of 17 776 patients died [6.5%]) (χ2 for trend, 3592.3; P < .001) (Figure, B).

    https://jamanetwork.com/journals/jam...gust%20(6.5%25).
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