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Future Virol
. 2020 Oct;15(10):663-671.
doi: 10.2217/fvl-2020-0142.
Clinical characteristics and outcomes of discharged COVID-19 patients with reoccurrence of SARS-CoV-2 RNA
Jing Wu 1 , Xiao-Ying Xia 1 , He-Lei Liu 1 , Hong Xia 1 , Wen-Xiang Huang 2 , Bei Jia 2 , Feng-Ying Peng 2
Affiliations
- PMID: 33224263
- PMCID: PMC7664131
- DOI: 10.2217/fvl-2020-0142
Abstract
Aim: Data are limited on clinical characteristics and outcomes of recovered the 2019 coronavirus disease (COVID-19) patients with the reoccurrence of SARS-CoV-2 RNA.
Patients & methods: Discharged patients in our hospital were included, who had recovered from COVID-19 with the reoccurrence of SARS-CoV-2 RNA.
Results: Six patients were redetectable and positive for SARS-CoV-2 RNA after discharge from 3 to 15 days. The main symptoms, although no fever, included fatigue, dry cough and pharyngeal or chest discomfort, which were generally milder in the repositive period compared with the period of initial infection. Their laboratory indexes were significantly improved compared with the initial infection, and the pulmonary lesions were continuously improving. All close contacts were SARS-CoV-2 RNA-negative.
Conclusion: No worsening outcomes or active transmission to close contacts were found for the repositive COVID-19 patients.
Keywords: COVID-19; SARS-CoV-2 RNA; clinical characteristics; discharge; outcomes; reoccurrence.