Emerg Infect Dis


. 2025 May;31(5):1006-1009.
doi: 10.3201/eid3105.241953.
Self-Reported SARS-CoV-2 Infections among National Blood Donor Cohort, United States, 2020-2022

Bryan R Spencer, Akintunde Akinseye, Eduard Grebe, Mars Stone, Karla G Zurita, David J Wright, James M Haynes, Susan L Stramer, Michael P BuschAbstract

SARS-CoV-2 case surveillance in the United States did not distinguish first infections from reinfections. In a large blood donor cohort, self-reported first infections and reinfections during 2020-2022 mirrored public health case count surveillance, and reinfection incidence peaked in 2022. Blood donor data could aid in SARS-CoV-2 and emerging infectious disease surveillance.

Keywords: COVID-19; SARS-CoV-2; United States; blood donors; health surveys; public health surveillance; respiratory infections; viruses.