A systematic review of COVID-19 and obstructive sleep apnoea

[Mary Wilson]

Sleep Medicine Reviews
Available online 8 September 2020, 101382
In Press, Journal Pre-proof

Michelle A.MillerPhD^aFrancesco P.Cappuccio^ab

https://doi.org/10.1016/j.smrv.2020.101382

Summary

The aims of the study were to review the rapidly emerging COVID-19 literature to determine (a) the relationship between obstructive sleep apnoea (OSA) and adverse COVID-19 outcomes and, (b) potential causal mechanisms (c) what effect COVID-19 has had on OSA diagnosis and (d) what effect COVID-19 has had on treatment and management of OSA during this period. PubMed was systematically searched up to 020620. Studies were included if they had examined the relationship between COVID-19 and OSA. Studies were included that were in English and had the full text available. The findings from this study suggest that many of the risk factors and co-morbidities associated for OSA which include obesity, hypertension and diabetes mellitus are associated with poor COVID-19 outcomes. There are plausible mechansims by which OSA may independently increase one’s risk of morbidity and mortality associated with COVID-19 and data from the newly published CORONADO study suggests that OSA treated patients may be at increased risk of death from COVID-19. It is clear that the pandemic has had a major effect on the treatment management and diagnosis of OSA and moving forward it may be necessary to explore new diagnosis and treatment pathways for these individuals.

https://www.sciencedirect.com/science/article/pii/S1087079220301258

[Mary Wilson]

Sleep apnea patients at greater risk of developing COVID-19 complications, study finds

Brooklyn Neustaeter
Published Monday, September 14, 2020 2:19PM EDT

TORONTO -- COVID-19 patients who have been diagnosed with obstructive sleep apnea may have a greater risk of adverse outcomes from the virus, according to a new U.K. study.

Researchers at the University of Warwick conducted a systematic review of studies that looked at COVID-19 patients and found that those who also had sleep apnea were at a higher risk of developing serious complications and dying.

"It is likely that COVID-19 increases oxidative stress and inflammation and has effects on the bradykinin pathways, all of which are also affected in obstructive sleep apnea patients," lead author Dr. Michelle Miller said in a press release.

https://www.ctvnews.ca/health/coronavirus/sleep-apnea-patients-at-greater-risk-of-developing-covid-19-complications-study-finds-1.5104190#_gus&_gucid=&_gup=twitter&_gsc=QwMsX3I